Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Hitomi Hakariya"'
Autor:
Mayu Onozato, Hiromi Nakazawa, Katsuyuki Ishimaru, Chihiro Nagashima, Minori Fukumoto, Hitomi Hakariya, Tatsuya Sakamoto, Hideaki Ichiba, Takeshi Fukushima
Publikováno v:
Heliyon, Vol 3, Iss 9 (2017)
Aims: d-Serine (d-Ser), a co-agonist of N-methyl-d-aspartate receptor (NMDAR), is effective for treating schizophrenia. The present study investigated changes in plasma and striatal d-Ser levels in Sprague-Dawley (SD) rats after intraperitoneal d-Ser
Externí odkaz:
https://doaj.org/article/d5f7c99924604d0da0524c4def962def
Autor:
Hiromi Nakazawa, Katsuyuki Ishimaru, Chihiro Nagashima, Mayu Onozato, Hitomi Hakariya, Tatsuya Sakamoto, Hideaki Iizuka, Miho Shishikura, Takeshi Fukushima, Hideaki Ichiba
Publikováno v:
Life sciences. 158
Aims Risperidone (Ris) is a second-generation antipsychotic (SGA) used to treat patients with schizophrenia. Additional interventions that increase plasma d -serine ( d -Ser) levels could provide improved amelioration of the negative symptoms of schi
Autor:
Sumiko Iwasa, Hideaki Ichiba, Miho Shishikura, Hitomi Hakariya, Takeshi Fukushima, Kiyoshi Fukui, Kazuko Yorita, Takashi Yoshio
Publikováno v:
Bioscience trends. 8(3)
It is of importance to determine whether antipsychotic drugs currently prescribed for schizophrenia exert D-amino acid oxidase (DAO)-inhibitory effects. We first investigated whether human (h)DAO can metabolize D-kynurenine (D-KYN) to produce the flu