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pro vyhledávání: '"Hitomi Ayabe"'
Autor:
Kazutaka Kitaura, Hiroshi Yamashita, Hitomi Ayabe, Tadasu Shini, Takaji Matsutani, Ryuji Suzuki
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
A diverse antibody repertoire is primarily generated by the rearrangement of V, D, and J genes and subsequent somatic hypermutation (SHM). Class-switch recombination (CSR) produces various isotypes and subclasses with different functional properties.
Externí odkaz:
https://doaj.org/article/287b82b1213e4187b7f830890fa9be2a