Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hitomi Arahori"'
Autor:
Sayaka Ikeda, Yutaka Ueda, Asami Yagi, Mariko Taniguchi, Satoko Matsuzaki, Tsuyoshi Takiuchi, Ai Miyoshi, Hitomi Arahori, Kei Hirai, Tadashi Kimura
Publikováno v:
BMC Public Health, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background In recent years, feelings of isolation among mothers caring for small children has become a significant social issue in Japan. The purpose of this study is to develop a message to alleviate their loneliness, to evaluate the impact
Externí odkaz:
https://doaj.org/article/a1645d478f3948b38a827675a92f1ac2
Autor:
Keiji Kawatani, Toshihiko Nambara, Nobutoshi Nawa, Hidetaka Yoshimatsu, Haruna Kusakabe, Katsuya Hirata, Akira Tanave, Kenta Sumiyama, Kimihiko Banno, Hidetoshi Taniguchi, Hitomi Arahori, Keiichi Ozono, Yasuji Kitabatake
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Keiji Kawatani et al. developed a panel of Down syndrome (DS) isogenic astrocytes derived from iPSCs to observe the consequence of DS on astrocyte precursor proliferation, differentiation, and gene expression. Their results suggest a dose-dependent e
Externí odkaz:
https://doaj.org/article/e91008f5d0604ea7bd9c6ba4cad7e588
Autor:
Katsuya Hirata, Toshihiko Nambara, Keiji Kawatani, Nobutoshi Nawa, Hidetaka Yoshimatsu, Haruna Kusakabe, Kimihiko Banno, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Hidetoshi Taniguchi, Hitomi Arahori, Kazuko Wada, Keiichi Ozono, Yasuji Kitabatake
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Abstract Individuals with Down syndrome (DS) commonly show unique pathological phenotypes throughout their life span. Besides the specific effects of dosage-sensitive genes on chromosome 21, recent studies have demonstrated that the gain of a chromos
Externí odkaz:
https://doaj.org/article/3cbef660897d48f4be8bf945fdb9d169
Autor:
Sayaka Omori, Hideyuki Tanabe, Kimihiko Banno, Ayumi Tsuji, Nobutoshi Nawa, Katsuya Hirata, Keiji Kawatani, Chikara Kokubu, Junji Takeda, Hidetoshi Taniguchi, Hitomi Arahori, Kazuko Wada, Yasuji Kitabatake, Keiichi Ozono
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Eukaryotic genomes are organised into complex higher-order structures within the nucleus, and the three-dimensional arrangement of chromosomes is functionally important for global gene regulation. The existence of supernumerary chromosome 21
Externí odkaz:
https://doaj.org/article/b025af64b00344728c5a37117dec64f6
Autor:
Nobutoshi Nawa, Katsuya Hirata, Keiji Kawatani, Toshihiko Nambara, Sayaka Omori, Kimihiko Banno, Chikara Kokubu, Junji Takeda, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Daisuke Okuzaki, Hidetoshi Taniguchi, Hitomi Arahori, Kazuko Wada, Yasuji Kitabatake, Keiichi Ozono
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219592 (2019)
Chromosome abnormalities induces profound alterations in gene expression, leading to various disease phenotypes. Recent studies on yeast and mammalian cells have demonstrated that aneuploidy exerts detrimental effects on organismal growth and develop
Externí odkaz:
https://doaj.org/article/7b30caad6ba543a59e1bcfe3f2b3c283
Autor:
Kimihiko Banno, Sayaka Omori, Katsuya Hirata, Nobutoshi Nawa, Natsuki Nakagawa, Ken Nishimura, Manami Ohtaka, Mahito Nakanishi, Tetsushi Sakuma, Takashi Yamamoto, Tsutomu Toki, Etsuro Ito, Toshiyuki Yamamoto, Chikara Kokubu, Junji Takeda, Hidetoshi Taniguchi, Hitomi Arahori, Kazuko Wada, Yasuji Kitabatake, Keiichi Ozono
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1228-1241 (2016)
Chromosomal aneuploidy and specific gene mutations are recognized early hallmarks of many oncogenic processes. However, the net effect of these abnormalities has generally not been explored. We focused on transient myeloproliferative disorder (TMD) i
Externí odkaz:
https://doaj.org/article/bbd99b1fc1324332a6cc8347311f497f
Autor:
Tokuo Miyazawa, Hitomi Arahori, Satoshi Ohnishi, Hromichi Shoji, Atsushi Matsumoto, Yuka Sano Wada, Naoto Takahashi, Toshimitsu Takayanagi, Satoshi Toishi, Ken Nagaya, Hisaya Hasegawa, Masahiro Hayakawa, Mariko Hida, Rie Fukuhara, Yasumasa Yamada, Masahiko Kawai, Kusaka Takashi, Kazuko Wada, Ichiro Morioka, Katsumi Mizuno
Publikováno v:
Pediatrics International. 65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e071011d8a92ea1b17a38633b936de5
https://doi.org/10.1111/ped.15493
https://doi.org/10.1111/ped.15493
Autor:
Tadashi Kimura, Mariko Taniguchi, Sayaka Ikeda, Hitomi Arahori, Asami Yagi, Ai Miyoshi, Kei Hirai, Tsuyoshi Takiuchi, Satoko Matsuzaki, Yutaka Ueda
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 47:4298-4305
AIM A feeling of isolation childcare mothers' face is a serious social problem in Japan because the relationships with mothers and local communities have grown sparser. The purpose of this study was to clarify the feelings of isolation of mothers dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebe108d3d941822088ddeec711a3459
https://doi.org/10.1111/jog.15039
https://doi.org/10.1111/jog.15039
Publikováno v:
Cureus.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1c8cdde67cec40756cdc1172199a3a9
https://doi.org/10.7759/cureus.28952
https://doi.org/10.7759/cureus.28952
Autor:
Katsuya Hirata, Hidetaka Yoshimatsu, Akira Tanave, Kenta Sumiyama, Haruna Kusakabe, Keiichi Ozono, Nobutoshi Nawa, Kimihiko Banno, Toshihiko Nambara, Keiji Kawatani, Yasuji Kitabatake, Hidetoshi Taniguchi, Hitomi Arahori
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Astrocytes exert adverse effects on the brains of individuals with Down syndrome (DS). Although a neurogenic-to-gliogenic shift in the fate-specification step has been reported, the mechanisms and key regulators underlying the accelerated proliferati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1aee42a50f734b0a2a1cee0bdbbc190
https://doi.org/10.1038/s42003-021-02242-7
https://doi.org/10.1038/s42003-021-02242-7