Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Hitomi, Sekine"'
Autor:
Miwa Nahata, Sachiko Mogami, Hitomi Sekine, Seiichi Iizuka, Naoto Okubo, Naoki Fujitsuka, Hiroshi Takeda
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 7, Iss 1, Pp 1-14 (2021)
Abstract Chronic undernutrition contributes to the increase in frailty observed among elderly adults, which is a pressing issue in the sector of health care for older people worldwide. Autophagy, an intracellular recycling system, is closely associat
Externí odkaz:
https://doaj.org/article/2976f3861c604a40a8c972724066b04e
Autor:
Taro Oshiro, Yumi Harada, Kunitsugu Kubota, Daichi Sadatomi, Hitomi Sekine, Mitsue Nishiyama, Naoki Fujitsuka
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 152, Iss , Pp 113263- (2022)
Changes in the intestinal microbiota are known to occur in constipated patients. Dietary fiber restriction presents obstacles to appropriate defecation and affects fecal properties, but the relationship between fecal microbiota and fecal morphologica
Externí odkaz:
https://doaj.org/article/aceae46b608c4adc9886e79375d236e7
Autor:
Chinami Matsumoto, Hitomi Sekine, Nana Zhang, Sachiko Mogami, Naoki Fujitsuka, Hiroshi Takeda
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9176 (2023)
Chemotherapy-induced sarcopenia is an unfavorable prognostic factor implicated in the development of postoperative complications and reduces the quality of life of patients with cancer. Skeletal muscle loss due to cisplatin use is caused by mitochond
Externí odkaz:
https://doaj.org/article/f95e49e47d144cc6bee8e74000c08430
Autor:
Miwa Nahata, Naoki Fujitsuka, Hitomi Sekine, Chika Shimobori, Katsuya Ohbuchi, Seiichi Iizuka, Sachiko Mogami, Shunsuke Ohnishi, Hiroshi Takeda
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Malnutrition impairs basic daily activities and leads to physical frailty, which is aggravated in the elderly compared with young adults. It is also well-known that the elderly are more vulnerable to metabolic stress. Therefore, in this study, using
Externí odkaz:
https://doaj.org/article/826f08799ed24f58a4c998facfea729e
Autor:
Yumi Harada, Hitomi Sekine, Kunitsugu Kubota, Daichi Sadatomi, Seiichi Iizuka, Naoki Fujitsuka
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss , Pp 111860- (2021)
EGFR tyrosine kinase inhibitors (TKIs) are mainly used to treat non-small cell lung cancer; however, adverse effects such as severe diarrhea represent a major obstacle towards the continuation of EGFR-TKIs therapy. Chloride channels, which control th
Externí odkaz:
https://doaj.org/article/f7fd0d0cf52a4ee58a9b95b1c6bf2a17
Autor:
Chinami, Matsumoto, Hitomi, Sekine, Miwa, Nahata, Sachiko, Mogami, Katsuya, Ohbuchi, Naoki, Fujitsuka, Hiroshi, Takeda
Publikováno v:
Biological and Pharmaceutical Bulletin. 45:780-792
Muscle atrophy is commonly observed during cisplatin chemotherapy, leading to a reduced QOL in cancer patients. Reduced skeletal muscle mass caused by cisplatin treatment results from the activation of ubiquitin ligases-Atrogin-1 and MuRF1, but the p
Autor:
Yoshihisa Sugimura, Yohei Kume, Hiroko Sakuma, Mitsuaki Hosoya, Makoto Sumikoshi, Hitomi Sekine
Publikováno v:
Clinical Pediatric Endocrinology
Childhood-onset lymphocytic infundibuloneurohypophysitis (LINH) due to infiltration of autoimmune lymphocyte in the neurohypophysis is rarely reported. Its definitive diagnosis requires a pituitary biopsy, which is an invasive procedure. Recently, an
Autor:
Kunitsugu Kubota, Yumi Harada, Hitomi Sekine, Naoki Fujitsuka, Seiichi Iizuka, Daichi Sadatomi
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 141, Iss, Pp 111860-(2021)
EGFR tyrosine kinase inhibitors (TKIs) are mainly used to treat non-small cell lung cancer; however, adverse effects such as severe diarrhea represent a major obstacle towards the continuation of EGFR-TKIs therapy. Chloride channels, which control th
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 369:466-472
Taste stimulants play important roles in triggering digestion and absorption of nutrients and in toxin detection, under the control of the gut-brain axis. Bitter compounds regulate gut hormone secretion and gastrointestinal motility through bitter ta
Autor:
Sachiko Mogami, Miwa Nahata, Hitomi Sekine, Naoki Fujitsuka, Shunsuke Ohnishi, Hiroshi Takeda
Publikováno v:
Gastroenterology. 162:S-1050