Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing.

Autor: Balke-Want, Hyatt¹ (AUTHOR), Keerthi, Vimal¹ (AUTHOR), Gkitsas, Nikolaos¹ (AUTHOR), Mancini, Andrew G.² (AUTHOR), Kurgan, Gavin L.³ (AUTHOR), Fowler, Carley¹ (AUTHOR), Xu, Peng¹ (AUTHOR), Liu, Xikun¹ (AUTHOR), Asano, Kyle¹ (AUTHOR), Patel, Sunny¹ (AUTHOR), Fisher, Christopher J.¹ (AUTHOR), Brown, Annie K.¹ (AUTHOR), Tunuguntla, Ramya H.¹ (AUTHOR), Patel, Shabnum¹ (AUTHOR), Sotillo, Elena¹ (AUTHOR), Mackall, Crystal L.¹ (AUTHOR) cmackall@stanford.edu, Feldman, Steven A.¹ (AUTHOR) feldmans@stanford.edu

Publikováno v: Molecular Cancer. 6/26/2023, Vol. 22 Issue 1, p1-16. 16p.

Optimization of HITI-Mediated Gene Insertion for Rhodopsin and Peripherin-2 in Mouse Rod Photoreceptors: Targeting Dominant Retinitis Pigmentosa.

Autor: Onishi A; Laboratory for Retinal Regeneration, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.; Cell and Gene Therapy in Ophthalmology Laboratory, RIKEN Baton Zone Program, Kobe, Japan.; Kobe City Eye Hospital Research Center, Kobe, Japan.; VCGT Inc., Kobe, Japan.; Research Organization of Science and Technology, Ritsumeikan University, Shiga, Japan., Tsunekawa Y; Laboratory for Cell Asymmetry, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.; Division of Molecular and Medical Genetics, Center for Gene and Cell Therapy, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan., Mandai M; Laboratory for Retinal Regeneration, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.; Kobe City Eye Hospital Research Center, Kobe, Japan.; Research Organization of Science and Technology, Ritsumeikan University, Shiga, Japan., Ishimaru A; Laboratory for Retinal Regeneration, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.; VCGT Inc., Kobe, Japan., Ohigashi Y; Laboratory for Retinal Regeneration, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.; Cell and Gene Therapy in Ophthalmology Laboratory, RIKEN Baton Zone Program, Kobe, Japan.; Vision Care Inc., Kobe, Japan., Sho J; Laboratory for Retinal Regeneration, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.; Cell and Gene Therapy in Ophthalmology Laboratory, RIKEN Baton Zone Program, Kobe, Japan.; Vision Care Inc., Kobe, Japan., Yasuda K; Cell and Gene Therapy in Ophthalmology Laboratory, RIKEN Baton Zone Program, Kobe, Japan.; VCGT Inc., Kobe, Japan., Suzuki K; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States.; Institute for Advanced Co-Creation Studies, Osaka University, Suita, Japan.; Graduate School of Engineering Science, Osaka University, Toyonaka, Japan., Izpisua Belmonte JC; Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, California, United States.; Altos Labs, Inc., San Diego, California, United States., Matsuzaki F; Laboratory for Cell Asymmetry, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.; Department of Aging Science and Medicine, Medical Innovation Center, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Takahashi M; Laboratory for Retinal Regeneration, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.; Cell and Gene Therapy in Ophthalmology Laboratory, RIKEN Baton Zone Program, Kobe, Japan.; Kobe City Eye Hospital Research Center, Kobe, Japan.; VCGT Inc., Kobe, Japan.; Vision Care Inc., Kobe, Japan.; Research Organization of Science and Technology, Ritsumeikan University, Shiga, Japan.

Publikováno v: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2024 Nov 04; Vol. 65 (13), pp. 38.

Hadi Numan Al-Hiti (press and career services)

Autor: Ahmed Jasem, Ahmed Rashid Juraithi

Publikováno v: مجلة جامعة الأنبار للعلوم الإنسانية, Vol 2022, Iss 1, Pp 301-318 (2022)

The dear province of Anbar gave birth to a large number of personalities who had a reputation in building the Iraqi state since its establishment in 1921 until the present day. The fields, and among those personalities that the people of Anbar have t

Externí odkaz: https://doaj.org/article/10113dbbc8184cba9953ae0d54373bea

The ECFA Early-Career Researchers Panel: Report for the year 2023

Autor: Allen, Julia, Alves, Bruno, Arling, Jan-Hendrik, Augsten, Kamil, Bagnaschi, Emanuele, Benato, Giovanni, Bennecke, Anna, Borca, Cecilia, Braz, Paulo, Brenner, Lydia, Degens, Jordy, Dengler, Yannick, Dimitriadi, Christina, Diociaiuti, Eleonora, Dufour, Laurent, Dunne, Patrick, Etisken, Ozgur, Ravasio, Silvia Ferrario, Fomin, Nikolai, Alonso, Andrea Garcia, Gellersen, Leif, Gsponer, Andreas, Herman, Tomas, Hiti, Bojan, Huhta, Laura, Ilg, Armin, Jarkovská, Kateřina, Jovicevic, Jelena, Keszeghova, Lucia, Kirschenmann, Henning, Klaver, Suzanne, Korajac, Arman, Kotsokechagia, Anastasia, Kussner, Meike, Lelek, Aleksandra, Lospalluto, Guiseppe, Major, Péter, Maksimovic, Veljko, Malczewski, Jakub, Benito, Carla Marin, Suarez, Paula Martinez, Milosevic, Vukasin, Modak, Atanu, Tarda, Arnau Morancho, Valero, Laura Moreno, Niel, Elisabeth, Nikiforou, Nikiforos, Novosel, Anja, Paakkinen, Petja, Pacey, Holly, Pedro, Rute, Pesut, Marko, Pietrzyk, Guillaume, Pitt, Michael, Placinta, Vlad-Mihai, Dash, Archita Rani, Räuber, Géraldine, Shopova, Mariana, Someonov, Radoslav, Simsek, Sinem, Skovpen, Kirill, Sopkova, Filomena, Souza, Fernando, Norella, Elisabetta Spadaro, Urbaniak, Marta, Gomez, Lourdes Urda, Wallin, Erik, Zaccolo, Valentina, Zardoshti, Nima, Zarnecki, Grzegorz

The European Committee for Future Accelerators (ECFA) Early-Career Researcher (ECR) panel, which represents the interests of the ECR community to ECFA, presents in this document its initiatives and activities in the year 2023. This report summarises

Externí odkaz: http://arxiv.org/abs/2407.12761

High temperature instruments and methods developed for supercritical geothermal reservoir characterisation and exploitation—The HiTI project

Autor: Ásmundsson, Ragnar, Pezard, Philippe, Sanjuan, Bernard, Henninges, Jan, Deltombe, Jean-Luc, Halladay, Nigel, Lebert, François, Gadalia, Alain, Millot, Romain, Gibert, Benoit, Violay, Marie, Reinsch, Thomas, Naisse, Jean-Marc, Massiot, Cécile, Azaïs, Pierre, Mainprice, David, Karytsas, Costas, Johnston, Colin

Publikováno v: In Geothermics January 2014 49:90-98