Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Hitesh Soni"'
Autor:
Olugbenga S. Michael, Praghalathan Kanthakumar, Hitesh Soni, Raji Rajesh Lenin, Kumar Abhiram Jha, Rajashekhar Gangaraju, Adebowale Adebiyi
Publikováno v:
Current Research in Physiology, Vol 7, Iss , Pp 100126- (2024)
Chronic kidney disease (CKD) is a progressive and long-term condition marked by a gradual decline in kidney function. CKD is prevalent among those with conditions such as diabetes mellitus, hypertension, and glomerulonephritis. Affecting over 10% of
Externí odkaz:
https://doaj.org/article/2dd23e71a942481baa3362385a26d0ac
Autor:
Ravi Kumar, Hitesh Soni, Jeremiah M. Afolabi, Praghalathan Kanthakumar, Pratheesh D. Mankuzhy, Samson A. Iwhiwhu, Adebowale Adebiyi
Publikováno v:
Redox Biology, Vol 55, Iss , Pp 102394- (2022)
Vasoactive endothelin (ET) is generated by ET converting enzyme (ECE)-induced proteolytic processing of pro-molecule big ET to biologically active peptides. H2O2 has been shown to increase the expression of ECE1 via transactivation of its promoter. T
Externí odkaz:
https://doaj.org/article/640eaf574c7d4e6981e444a0a565997e
Autor:
Hitesh Soni, Taisiya Yakimkova, Anberitha T. Matthews, Paul K. Amartey, Robert W. Read, Randal K. Buddington, Adebowale Adebiyi
Publikováno v:
Redox Report, Vol 24, Iss 1, Pp 10-16 (2019)
Objective: Oxidative stress, a common feature in cardiovascular and renal disease is associated with the causes and consequences of fetal growth restriction. Hence, renal redox status is likely an early determinant of morbidity in small-for-gestation
Externí odkaz:
https://doaj.org/article/74fecd5398ef447f91f5310e06f14b39
Publikováno v:
Renal Failure, Vol 40, Iss 1, Pp 314-322 (2018)
Acute kidney injury (AKI), a significant complication of cisplatin chemotherapy is associated with reactive oxygen species (ROS)-dependent renal cell death, but the cellular targets of ROS in cisplatin nephrotoxicity are not fully resolved. Here, we
Externí odkaz:
https://doaj.org/article/5a66c837c78942f2ba7f23b5e804e477
Autor:
Anberitha T. Matthews, Hitesh Soni, Katherine E. Robinson-Freeman, Theresa A. John, Randal K. Buddington, Adebowale Adebiyi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7589 (2021)
Doxorubicin (DOX), a category D pregnancy drug, is a chemotherapeutic agent that has been shown in animal studies to induce fetal toxicity, including renal abnormalities. Upregulation of the transient receptor potential cation (TRPC) 6 channel is inv
Externí odkaz:
https://doaj.org/article/57d4f7099e2747de8ef3de8eace38616
Autor:
Jeremiah M Afolabi, Praghalathan Kanthakumar, Jada D Williams, Ravi Kumar, Hitesh Soni, Adebowale Adebiyi
Publikováno v:
Function.
In patients with rhabdomyolysis, the overwhelming release of myoglobin into circulation is the primary cause of kidney injury. Myoglobin causes direct kidney injury as well as severe renal vasoconstriction. An increase in renal vascular resistance (R
Autor:
Olugbenga Michael, Jeremiah Afolabi, Olufunke Falayi, Praghalathan Kanthakumar, Pratheesh Mankuzhy, Hitesh Soni, Adebowale Adebiyi
Publikováno v:
Physiology. 38
Control of microvascular reactivity by 5-hydroxytryptamine (5-HT; serotonin) is complex and may depend on vascular bed type and 5-HT receptors. 5-HT receptors consist of seven families (5-HT1-5-HT7), with 5-HT2 predominantly mediating renal vasoconst
Autor:
Jeremiah M. Afolabi, Olugbenga S. Michael, Olufunke O. Falayi, Praghalathan Kanthakumar, Pratheesh D. Mankuzhy, Hitesh Soni, Adebowale Adebiyi
Publikováno v:
Microvascular Research. 148:104516
Autor:
Hitesh Soni
Publikováno v:
Current Drug Targets. 22:1825-1831
The socio-economic burden of renal disease is enormous due to the unavailability of effective treatment to cure it. High risk patients have only two costly options in chronic renal disease, dialysis and renal replacement therapy (RRT). RRT has limita
Publikováno v:
The FASEB Journal. 36