Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hitesh R. Bhagat"'
Autor:
Ranjani V. Nellore, Hitesh R. Bhagat
Publikováno v:
Drug Delivery. 4:49-55
The effects of solvent treatment and physical stresses encountered by the model protein ribonuclease A (RNase A) during microencapsulation into biodegradable polymeric microspheres were examined. Stability of the protein at each step of the microenca
Publikováno v:
Drug Development and Industrial Pharmacy. 23:687-694
The main objective of this study was to prepare pellets in a Roto-processor using the powder-layering process onto inert nonpareils and to evaluate the applicability of the Roto-processor setup for film coating. Nonpareils were loaded with phenylprop
Publikováno v:
Cell & Tissue Research. 279:433-436
In this study, we demonstrate the role of M cells in uptake of poly(D-L-lactic-co-glycolic acid) (PLGA) microspheres and transport into rabbit Peyer's patches. Microspheres 1 to 10 microns in diameter composed of 50:50 lactic acid:glycolic acid were
Publikováno v:
Drug Development and Industrial Pharmacy. 20:387-394
Compressed tablets containing guaifenesin (model drug), calcium acetate (reactant) and pharmaceutical excipients were prepared. The tablets were coated with calcium alginate hydrogel using a novel, self-correcting membrane coating technique. Effects
Publikováno v:
Drug Development and Industrial Pharmacy. 20:1725-1737
Methotrexate-loaded biodegradable polyanhydride microspheres were prepared by modified hot-melt technique and aqueous solvent evaporation technique. The effect of particle size, drug loading and microencapsulation technique on the in vitro drug relea
Autor:
Carol O. Tacket, Genevieve Losonsky, Edgar C. Boedeker, Robert R. Edelman, Hitesh R. Bhagat, James P. Nataro, Robert H. Reid
Publikováno v:
Vaccine. 12:1270-1274
The development of a safe and effective vaccine against enterotoxigenic Escherichia coli (ETEC) would be useful for travellers and for young children in endemic areas. A feasibility study of an enteral ETEC vaccine prototype consisting of colonizatio
Publikováno v:
Analytical Letters. 26:657-664
The objective of this study was to develop an analytical technique for the assay of murabutide, a synthetic peptide, by high performance capillary electrophoresis. The analyte concentration was monitored by UV detection. Murabutide was eluted by usin
Autor:
Ranjani V. Nellore, Charles E. Mcqueen, L.-Y. Tseng, C.L. Wilhelmsen, Robert H. Reid, Edgar C. Boedeker, K Sau, P. Dalal, J. Kodak, D. Davis, Hitesh R. Bhagat
Publikováno v:
Vaccine. 11:159-167
Colonization Factor Antigen (CFA/II) from enterotoxigenic Escherichia coli (ETEC) prepared under good manufacturing practices (GMP) was successfully incorporated into biodegradable poly(D,L-lactide-co-glycolide) (PLGA) polymer microspheres (BPM) unde
Publikováno v:
Pharmaceutical Research. :576-583
A novel coating process, leading to formation of uniform, defect-free coating on solid dosage forms, is proposed. The coating process, termed “diffusion-controlled interfacial complexation,” involves a chemical reaction between a reactant incorpo