Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Hitesh J. Sanganee"'
Autor:
Evan T. Keller, Laurie K. McCauley, Zhi Yao, Hitesh J. Sanganee, Katherine J. Escott, Jill M. Keller, Joe L. Sottnik, Honglai Zhang, Jinlu Dai, Yuan Jiang
PDF file - 391K, Figure S5. Knockdown of β-catenin abrogates the ability of AR79 to increase nuclear B-catenin expression in DU145 and C4-2B cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1baef461105a60f0c0f9682943a6eec
https://doi.org/10.1158/1541-7786.22509189.v1
https://doi.org/10.1158/1541-7786.22509189.v1
Autor:
Evan T. Keller, Laurie K. McCauley, Zhi Yao, Hitesh J. Sanganee, Katherine J. Escott, Jill M. Keller, Joe L. Sottnik, Honglai Zhang, Jinlu Dai, Yuan Jiang
PDF file - 290K, Figure S2. AR79 has no impact on p-HIPK2 expression in prostate cancer cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3af3059ba0c867921cb34cac61d19b
https://doi.org/10.1158/1541-7786.22509198
https://doi.org/10.1158/1541-7786.22509198
Autor:
Evan T. Keller, Laurie K. McCauley, Zhi Yao, Hitesh J. Sanganee, Katherine J. Escott, Jill M. Keller, Joe L. Sottnik, Honglai Zhang, Jinlu Dai, Yuan Jiang
PDF file - 56K, DNA profiling of LNCaP, C4-2B and DU145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4246fac7a52f2c502047d2d7ab8f5d95
https://doi.org/10.1158/1541-7786.22509183.v1
https://doi.org/10.1158/1541-7786.22509183.v1
Autor:
Evan T. Keller, Laurie K. McCauley, Zhi Yao, Hitesh J. Sanganee, Katherine J. Escott, Jill M. Keller, Joe L. Sottnik, Honglai Zhang, Jinlu Dai, Yuan Jiang
PDF file - 66K, Figure S1. Mouse body weights were not impacted by AR79 treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ad7176368e41e5cf02db1b6b6bc6a3
https://doi.org/10.1158/1541-7786.22509201
https://doi.org/10.1158/1541-7786.22509201
Autor:
Evan T. Keller, Laurie K. McCauley, Zhi Yao, Hitesh J. Sanganee, Katherine J. Escott, Jill M. Keller, Joe L. Sottnik, Honglai Zhang, Jinlu Dai, Yuan Jiang
PDF file - 200K, Figure S4. AR79 increases the cell number of Du145luc cells in the presence or absence of ST-2 co-culture.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e02efa9521fbd276520194aa8843c7
https://doi.org/10.1158/1541-7786.22509192
https://doi.org/10.1158/1541-7786.22509192
Autor:
Evan T. Keller, Laurie K. McCauley, Zhi Yao, Hitesh J. Sanganee, Katherine J. Escott, Jill M. Keller, Joe L. Sottnik, Honglai Zhang, Jinlu Dai, Yuan Jiang
Due to its bone anabolic activity, methods to increase Wnt activity, such as inhibitors of dickkopf-1 and sclerostin, are being clinically explored. Glycogen synthase kinase (GSK3β) inhibits Wnt signaling by inducing β-catenin degradation, and a GS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cffbedab4bd84ca77eec1018a36a7011
https://doi.org/10.1158/1541-7786.c.6539223.v1
https://doi.org/10.1158/1541-7786.c.6539223.v1
Autor:
Evan T. Keller, Laurie K. McCauley, Zhi Yao, Hitesh J. Sanganee, Katherine J. Escott, Jill M. Keller, Joe L. Sottnik, Honglai Zhang, Jinlu Dai, Yuan Jiang
PDF file - 294K, Figure S3. AR79 increases bone formation in normal mouse tibiae.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805c9633903b34357013d2af5d2116d1
https://doi.org/10.1158/1541-7786.22509195.v1
https://doi.org/10.1158/1541-7786.22509195.v1
Autor:
Evan T. Keller, Laurie K. McCauley, Zhi Yao, Hitesh J. Sanganee, Katherine J. Escott, Jill M. Keller, Joe L. Sottnik, Honglai Zhang, Jinlu Dai, Yuan Jiang
PDF file - 56K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825305937dfc29e666521064020759c5
https://doi.org/10.1158/1541-7786.22509186
https://doi.org/10.1158/1541-7786.22509186
Autor:
Amelie Joffrin, Vikki Flemington, Alex M Saunders, Hitesh J. Sanganee, David Barneda, Amber L. Thompson, Stuart J. Conway
Synthetic phosphatidylinositol phosphate (PtdInsPn) derivatives play a pivotal role in broadening our understanding of PtdInsPn metabolism. However, the development of such tools is reliant on efficient enantioselective and regioselective synthetic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68505c471f70ce24ce26f7a956b980f8
https://ora.ox.ac.uk/objects/uuid:cc773e75-d83c-482b-bbb7-980fd1ec888d
https://ora.ox.ac.uk/objects/uuid:cc773e75-d83c-482b-bbb7-980fd1ec888d
Autor:
Kostas Karabelas, Ulf Andersson, Lisa Jinton, Ulf Sivars, Leif Hultin, Joakim Larsson, Cristina Gardelli, Brith Leidvik, Karin Gedda, Marie Rydén Landergren, Igor L. Shamovsky, Hiroki Wada, Kristina Stenvall, Asim K. Ray, Moya Caffrey, Hitesh J. Sanganee, Joakim Tholander, Antonio Llinas
Publikováno v:
Journal of Medicinal Chemistry. 61:5974-5987
Cachexia and muscle wasting are very common among patients suffering from cancer, chronic obstructive pulmonary disease, and other chronic diseases. Ghrelin stimulates growth hormone secretion via the ghrelin receptor, which subsequently leads to inc