Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hitendra Negi"'
Autor:
Varvara Folimonova, Xiang Chen, Hitendra Negi, Charles D. Schwieters, Jess Li, R. Andrew Byrd, Naomi Taylor, Philippe Youkharibache, Kylie J. Walters
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract T-cell therapies based on chimeric antigen receptor (CAR) targeting of a tumor-specific antigen offer hope for patients with relapsed or refractory cancers. CAR hinge and transmembrane regions link antigen recognition domains to intracellula
Externí odkaz:
https://doaj.org/article/b4c10e34cd6b426a9a8bdea815cc3474
Publikováno v:
eLife, Vol 13 (2024)
The proteasome controls levels of most cellular proteins, and its activity is regulated under stress, quiescence, and inflammation. However, factors determining the proteasomal degradation rate remain poorly understood. Proteasome substrates are conj
Externí odkaz:
https://doaj.org/article/7e37d30389dd4893a903b5e53111d161
Autor:
Neha Nandwani, Parag Surana, Hitendra Negi, Nahren M. Mascarenhas, Jayant B. Udgaonkar, Ranabir Das, Shachi Gosavi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Designing interfaces that can induce protein-protein interactions is a challenging problem. Here the authors show that a five amino acid sequence known to mediate domain swapping in cystatins can drive oligomerization when grafted onto functionally a
Externí odkaz:
https://doaj.org/article/9b6bdc87e3ab4b35a3fc024b6c07e914
Autor:
Goutham Hassan Venkatesh, Vadhiraja Bejadi Manjunath, Kamalesh Dattaram Mumbrekar, Hitendra Negi, Donald Jerard Fernandes, Krishna Sharan, Sourjya Banerjee, Satish Rao Bola Sadashiva
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e89079 (2014)
Cellular and molecular approaches are being explored to find a biomarker which can predict the development of radiation induced acute toxicity prior to radiation therapy. SNPs in radiation responsive genes may be considered as an approach to develop
Externí odkaz:
https://doaj.org/article/b89330659089482ab27735d60a49bbc3
The proteasome machinery regulates the levels of most cellular proteins. However, the factors determining rate of proteasomal degradation remain poorly understood. A rate-limiting step of degradation is the mechanical unfolding of substrates by prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::536ef1ece194c8802d2a05621d0a1739
https://doi.org/10.1101/2022.07.15.499953
https://doi.org/10.1101/2022.07.15.499953
Autor:
Pothula Purushotham Reddy, Vineeth Vengayil, Sunil Laxman, Hitendra Negi, Ranabir Das, Chhaya Patole
Publikováno v:
The Biochemical journal. 477(12)
The Baculoviridae family of viruses encode a viral Ubiquitin (vUb) gene. Though the vUb is homologous to the host eukaryotic Ubiquitin (Ub), its preservation in the viral genome indicates unique functions that are not compensated by the host Ub. We r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8657892b2d7e81b7cad5f240fb6d8de0
https://pubmed.ncbi.nlm.nih.gov/32478812
https://pubmed.ncbi.nlm.nih.gov/32478812
TheBaculoviridaefamily of viruses encode a viral Ubiquitin gene. Although the viral Ubiquitin is homologous to eukaryotic Ubiquitin (Ub), preservation of this gene in the viral genome indicates a unique function that is absent in the host eukaryotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2540ad42ebb300699ae44eb3005cd58
https://doi.org/10.1101/756791
https://doi.org/10.1101/756791
Autor:
Vasvi Tripathi, D.S.S. Hembram, Ranabir Das, Hitendra Negi, D. Shet, Poulomi Biswas, Vikas Kumar, Lokesh Bhushan
When the herpes simplex virus (HSV) genome enters the nucleus for replication and transcription, phase-segregated nuclear protein bodies called Promyelocytic leukemia protein nuclear bodies (PML NBs) colocalize with the genome and repress it. HSV enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2549a27d8ad7130583c398aff4af4af
https://doi.org/10.1101/709485
https://doi.org/10.1101/709485
Autor:
Parag Surana, Jayant B. Udgaonkar, Ranabir Das, Nahren Manuel Mascarenhas, Hitendra Negi, Neha Nandwani, Shachi Gosavi
Publikováno v:
'Nature Communications ', vol: 10, pages: 452-1-452-13 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Domain swapping is the process by which identical monomeric proteins exchange structural elements to generate dimers/oligomers. Although engineered domain swapping is a compelling strategy for protein assembly, its application has been limited due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823d2a64a60fab746670e8d32af43abf
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:51288
https://epn-library.esrf.fr/flora/jsp/index_view_direct_anonymous.jsp?record=doc:PUB_ESRF:51288
Autor:
Kamalesh Dattaram Mumbrekar, Vadhiraja Bejadi Manjunath, Donald J Fernandes, Satish Rao Bola Sadashiva, Krishna Sharan, Goutham Hassan Venkatesh, Sourjya Banerjee, Hitendra Negi
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e89079 (2014)
PLoS ONE
PLoS ONE
Cellular and molecular approaches are being explored to find a biomarker which can predict the development of radiation induced acute toxicity prior to radiation therapy. SNPs in radiation responsive genes may be considered as an approach to develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b5fd2a2ab8afafcc1a5084858a497c7
http://europepmc.org/articles/PMC3942321?pdf=render
http://europepmc.org/articles/PMC3942321?pdf=render