Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Histones/genetics/*metabolism"'
Autor:
Nathaniel A. Hathaway, Yafeng He, Gerald R. Crabtree, Kathrin Muegge, Simon M. G. Braun, Richard Finney, Jianke Ren, Kai Ni, Xiaoping Xu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications
Nature Communications, Vol. 11, No 1 (2020) P. 5647
Nature Communications
Nature Communications, Vol. 11, No 1 (2020) P. 5647
The human Immunodeficiency Centromeric Instability Facial Anomalies (ICF) 4 syndrome is a severe disease with increased mortality caused by mutation in the LSH gene. Although LSH belongs to a family of chromatin remodeling proteins, it remains unknow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4732fd1268110817593e7cbec47d2015
Autor:
Karoutas, A., Szymanski, W., Rausch, T., Guhathakurta, S., Rog-Zielinska, E. A., Peyronnet, R., Seyfferth, J., Chen, H. R., de Leeuw, R., Herquel, B., Kimura, Hiroshi, Mittler, G., Kohl, P., Medalia, O., Korbel, J. O., Akhtar, A.
Publikováno v:
Nature Cell Biology
While nuclear lamina abnormalities are hallmarks of human diseases, their interplay with epigenetic regulators and precise epigenetic landscape remain poorly understood. Here, we show that loss of the lysine acetyltransferase MOF or its associated NS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3548ff4d5435a5924760feb5f54ba9
https://doi.org/10.5167/uzh-176015
https://doi.org/10.5167/uzh-176015
Autor:
Robert L. Margolis, Michael A. Lampson, Ana Losada, Andrew D. McAinsh, M. Fitzgerald-Hayes, Barbara G. Mellone, Bill R. Brinkley, Jason R. Swedlow, Gregory P. Copenhaver, Robin C. Allshire, Stephen C. Harrison, Kinya Yoda, Susanne M.A. Lens, Gary J. Gorbsky, Gary H. Karpen, Don W. Cleveland, Kerry Bloom, Geert J. P. L. Kops, Lars E.T. Jansen, Andrea Musacchio, Stephan Diekmann, David M. Glover, Daniel R. Foltz, Ben E. Black, T. J. Yen, William Brown, Toru Hirota, Beth A. Sullivan, Iain M. Cheeseman, Aaron F. Straight, Huntington F. Willard, Paul S. Maddox, William C. Earnshaw, Jennifer G. DeLuca, Mitsuhiro Yanagida, Patrick Heun, Daniel W. Gerlich, Hiroshi Masumoto, Kristin C. Scott, Rachel J. O’Neill, Karolin Luger, Reto Gassmann, Karen Oegema, Helder Maiato, Stefan Westermann, Patrick Meraldi, Claudio E. Sunkel, P. T. Stukenberg, Choo Kh, Kevin F. Sullivan, Tatsuo Fukagawa, Peter E. Warburton, Sylvia Erhardt, Edward D. Salmon, Claire E. Walczak, Arshad Desai, Linda Wordeman
Publikováno v:
Earnshaw, B, Allshire, R, Black, B E, Bloom, K, Salmon, E D, Brinkley, B R, Brown, W, Cheesman, I M, Choo, K H A, Copenhaver, G P, DeLuca, J G & (47 other authors), E A 2013, ' Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant ', Chromosome Research, vol. 21, no. 2, pp. 101-106 . https://doi.org/10.1007/s10577-013-9347-y
Chromosome Research
CHROMOSOME RESEARCH
Chromosome Research; Vol 21
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, vol 21, iss 2
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PMC
Chromosome Research, Vol. 21, No 2 (2013) pp. 101-6
Chromosome Research
CHROMOSOME RESEARCH
Chromosome Research; Vol 21
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, vol 21, iss 2
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
PMC
Chromosome Research, Vol. 21, No 2 (2013) pp. 101-6
The first centromeric protein identified in any species was CENP-A, a divergent member of the histone H3 family that was recognised by autoantibodies from patients with scleroderma-spectrum disease. It has recently been suggested to rename this prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3de3fd9f40890f317f2dfa20715a13
https://doi.org/10.1007/s10577-013-9347-y
https://doi.org/10.1007/s10577-013-9347-y
Autor:
Hinrich Gronemeyer, Matthias Blum, Pierre-Etienne Cholley, Mohamed-Ashick M. Saleem, Marco Antonio Mendoza-Parra
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, 2017, 18 (1), ⟨10.1186/s12859-017-1655-3⟩
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-9 (2017)
BMC Bioinformatics, 2017, 18 (1), ⟨10.1186/s12859-017-1655-3⟩
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-9 (2017)
Background Exponentially increasing numbers of NGS-based epigenomic datasets in public repositories like GEO constitute an enormous source of information that is invaluable for integrative and comparative studies of gene regulatory mechanisms. One of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8be2de526eeca409188f6eaead22b47
https://hal.science/hal-03677828
https://hal.science/hal-03677828
Publikováno v:
Chromosome Research
DNA cytosine methylation (5mC) is indispensable for a number of cellular processes, including retrotransposon silencing, genomic imprinting, and X chromosome inactivation in mammalian development. Recent studies have focused on 5-hydroxymethylcytosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55f8fc17a76282077e76bcb0b3e34e8
https://doi.org/10.1007/s10577-012-9317-9
https://doi.org/10.1007/s10577-012-9317-9
Autor:
Numa, H., Kim, J. M., Matsui, A., Kurihara, Y., Morosawa, T., Ishida, J., Mochizuki, Y., Kimura, Hiroshi, Shinozaki, K., Toyoda, T., Seki, M., Yoshikawa, M., Habu, Y.
Publikováno v:
The EMBO journal. 29(No. 2):352-62
RNA-directed modification of histones is essential for the maintenance of heterochromatin in higher eukaryotes. In plants, cytosine methylation is an additional factor regulating inactive chromatin, but the mechanisms regulating the coexistence of cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c0b11037daa6082202b4ac5f8295d9
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100733715
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100733715
Autor:
Inagaki, S., Miura-Kamio, A., Nakamura, Y., Lu, F., Cui, X., Cao, X., Kimura, Hiroshi, Saze, H., Kakutani, T.
Publikováno v:
The EMBO journal. 29(No. 20):3496-506
In diverse eukaryotes, constitutively silent sequences, such as transposons and repeats, are marked by methylation at histone H3 lysine 9 (H3K9me). Although selective H3K9me is critical for maintaining genome integrity, mechanisms to exclude H3K9me f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f86f1302a2c51e67c7423c3b6e566e7
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100733710
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100733710
Publikováno v:
Molecular Cell, Vol. 35, No 3 (2009) pp. 377-83
Molecular cell
Molecular cell
Nucleosomes are surprisingly dynamic structures in vivo, showing transcription-independent exchange of histones H2A-H2B genome-wide and exchange of H3-H4 mainly within the promoters of transcribed genes. In addition, nucleosomes are disrupted in fron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ade36840b12b47f5536e63827d70d652
Autor:
Ishtiaq Ahmad, Evelyne Walker-Nasir, Daniel C. Hoessli, Afshan Kaleem, Nasir-ud-Din, Anwar Nasim, Abdul Rauf Shakoori
Publikováno v:
Journal of cellular biochemistry, Vol. 103, No 3 (2008) pp. 835-51
In mammalian cells, induction of immediate-early (IE) gene transcription occurs concomitantly with histone H3 phosphorylation on Ser 10 and is catalyzed by mitogen-activated protein kinases (MAPKs). Histone H3 is an evolutionarily conserved protein l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8d06131db31f14b56cb2549dd12660
https://doi.org/10.1002/jcb.21454
https://doi.org/10.1002/jcb.21454
Autor:
Nunzia Scibetta, Lucie Bourgoin, Marion Peyrou, Roger Williams, Valerio Pazienza, Arianna Marino, Gianluigi Mazzoccoli, Francesca Rappa, Azzura Greco, Manlio Vinciguerra, Francesco Cappello, Michelangelo Foti, Christine Podrini, Massimo Federici
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54458 (2013)
PloS one
PLOS ONE, Vol. 8, No 1 (2013) P. e54458
PLoS ONE
PloS one
PLOS ONE, Vol. 8, No 1 (2013) P. e54458
PLoS ONE
BackgroundHepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Prevention and risk reduction are important and the identification of specific biomarkers for early diagnosis of HCC represents an active field of research. Increas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965fea8e93a5149cecd15198a7f2450f
http://hdl.handle.net/10447/73063
http://hdl.handle.net/10447/73063