Zobrazeno 1 - 10
of 1 384
pro vyhledávání: '"Histone variant"'
Autor:
Takayuki Kawaguchi, Michihiro Hashimoto, Reiko Nakagawa, Ryunosuke Minami, Masahito Ikawa, Jun-ichi Nakayama, Jun Ueda
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract During the development of multicellular organisms and cell differentiation, the chromatin structure in the cell nucleus undergoes extensive changes, and the nucleosome structure is formed by a combination of various histone variants. Histone
Externí odkaz:
https://doaj.org/article/1e02e983aa29483a896fc72785bb3fdf
Autor:
Khalid Ouararhni, Flore Mietton, Jamal S. M. Sabir, Abdulkhaleg Ibrahim, Annie Molla, Raed S. Albheyri, Ali T. Zari, Ahmed Bahieldin, Hervé Menoni, Christian Bronner, Stefan Dimitrov, Ali Hamiche
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background The histone variant macroH2A (mH2A), the most deviant variant, is about threefold larger than the conventional histone H2A and consists of a histone H2A-like domain fused to a large Non-Histone Region responsible for recruiting PA
Externí odkaz:
https://doaj.org/article/9e382b68c4fc43db96018983890a6689
Autor:
Anna K. Atanasoff-Kardjalieff, Harald Berger, Katharina Steinert, Slavica Janevska, Nadia Ponts, Hans-Ulrich Humpf, Svetlana Kalinina, Lena Studt-Reinhold
Publikováno v:
Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-23 (2024)
Abstract Background Fusarium fujikuroi is a pathogen of rice causing diverse disease symptoms such as ‘bakanae’ or stunting, most likely due to the production of various natural products (NPs) during infection. Fusaria have the genetic potential
Externí odkaz:
https://doaj.org/article/30569c65304e4b949c99f555eb976845
Autor:
Hsiao P. J. Voon, Linda Hii, Andrew Garvie, Maheshi Udugama, Brian Krug, Caterina Russo, Anderly C. Chüeh, Roger J. Daly, Alison Morey, Toby D. M. Bell, Stephen J. Turner, Joseph Rosenbluh, Paul Daniel, Ron Firestein, Jeffrey R. Mann, Philippe Collas, Nada Jabado, Lee H. Wong
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-27 (2023)
Abstract Background Point mutations in histone variant H3.3 (H3.3K27M, H3.3G34R) and the H3.3-specific ATRX/DAXX chaperone complex are frequent events in pediatric gliomas. These H3.3 point mutations affect many chromatin modifications but the exact
Externí odkaz:
https://doaj.org/article/1023758b231c48e2b46f0fc49daf209d
Autor:
Ting Yu, Yancui Wang, Pingping Xu, Senan Cheng, Xinwei Hou, Guofeng Geng, Zhiqiang Pan, Shukai Wang, Dusheng Lu, Shubo Gu, Xitong Xu, Zhixin Liu, Cuixia Chen
Publikováno v:
GCB Bioenergy, Vol 15, Iss 8, Pp 1058-1073 (2023)
Abstract Miscanthus is a perennial forage plant with great potential for high stress tolerance and biomass yield. It has strong adaptability for growing in saline land and avoids competition with grain crops in arable lands. However, little is known
Externí odkaz:
https://doaj.org/article/62536f50d06b4bc18fb52be9ff6d354d
Publikováno v:
The Journal of Reproduction and Development, Vol 69, Iss 3, Pp 178-182 (2023)
Linker histone variants regulate higher-order chromatin structure and various cellular processes. It has been suggested that linker histone variant H1a loosens chromatin structure and activates transcription. However, its role in early mouse developm
Externí odkaz:
https://doaj.org/article/bbda87dfd1a342aabbea24021deed378
Autor:
Syed Nabeel-Shah, Jyoti Garg, Kanwal Ashraf, Renu Jeyapala, Hyunmin Lee, Alexandra Petrova, James D. Burns, Shuye Pu, Zhaolei Zhang, Jack F. Greenblatt, Ronald E. Pearlman, Jean-Philippe Lambert, Jeffrey Fillingham
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-22 (2023)
Abstract Background Eukaryotic cells can rapidly adjust their transcriptional profile in response to molecular needs. Such dynamic regulation is, in part, achieved through epigenetic modifications and selective incorporation of histone variants into
Externí odkaz:
https://doaj.org/article/e4f36e6d55c941bfb45b7fa551f9ce48
Publikováno v:
Epigenomes, Vol 8, Iss 2, p 21 (2024)
Variant H3.3, along with H2A.Z, is notably enriched at promoter regions and is commonly associated with transcriptional activation. However, the specific molecular mechanisms through which H3.3 influences chromatin dynamics at transcription start sit
Externí odkaz:
https://doaj.org/article/e2e1e31dec8248099673956a164316c4
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 299-311 (2023)
Histone proteins are highly conserved among all eukaryotes. They have two important functions in the cell: to package the genomic DNA and to regulate gene accessibility. Fundamental to these functions is the ability of histone proteins to interact wi
Externí odkaz:
https://doaj.org/article/5d219bdefcab41c793f5c96e1729ef83
Autor:
Bhagyshree Jamge, Zdravko J Lorković, Elin Axelsson, Akihisa Osakabe, Vikas Shukla, Ramesh Yelagandula, Svetlana Akimcheva, Annika Luisa Kuehn, Frédéric Berger
Publikováno v:
eLife, Vol 12 (2023)
How different intrinsic sequence variations and regulatory modifications of histones combine in nucleosomes remain unclear. To test the importance of histone variants in the organization of chromatin we investigated how histone variants and histone m
Externí odkaz:
https://doaj.org/article/dac2ee6289964c7d9ca29f8ff76e2ac6