Zobrazeno 1 - 10
of 2 418
pro vyhledávání: '"Histone demethylase"'
Publikováno v:
口腔疾病防治, Vol 32, Iss 6, Pp 463-469 (2024)
Histone acetylation and methylation can affect chromatin conformation and regulate a variety of biological activities. Abnormal histone acetylation and methylation modifications are related to the occurrence and development of a variety of oral disea
Externí odkaz:
https://doaj.org/article/c83ef6d393f2414eb80d6e994ab2d980
Akademický článek
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Akademický článek
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Publikováno v:
Plant Stress, Vol 11, Iss , Pp 100303- (2024)
Abiotic stress greatly threaten plants’ growth and ultimately impact crop productivity. Plants have evolved sophisticated regulatory mechanisms to cope with stressful conditions, including undergoing physiological changes through genetic and epigen
Externí odkaz:
https://doaj.org/article/7292947df6e94893bf7de7868c95f8e7
Autor:
Hyun-Min Kim, Zifei Liu
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 553 (2024)
Histone demethylases, enzymes responsible for removing methyl groups from histone proteins, have emerged as critical players in regulating gene expression and chromatin dynamics, thereby influencing various cellular processes. LSD2 and LSD1 have attr
Externí odkaz:
https://doaj.org/article/42e123ffb5b94a7898edf678453e4e04
Autor:
Heting Tang, Yaping Guan, Zhihao Yuan, Tuanjie Guo, Xiangyin Tan, Yu Fan, Encheng Zhang, Xiang Wang
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Advanced renal cell carcinoma (RCC) poses a threat to patient survival. Epigenetic remodelling is the pathogenesis of renal cancer. Histone demethylase 4B (KDM4B) is overexpressed in many cancers through various pathways. However, the role of KDM4B i
Externí odkaz:
https://doaj.org/article/9cb3f8f6fc734ff19163084e83c3c06c
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
How the function of the JMJD2D epigenetic regulator is regulated or whether it plays a role in prostate cancer has remained elusive. We found that JMJD2D was overexpressed in prostate tumors, stimulated prostate cancer cell growth and became methylat
Externí odkaz:
https://doaj.org/article/98703971f8d74952b58ab49316928a02
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Background KDM5 family proteins are multi-domain regulators of transcription that when dysregulated contribute to cancer and intellectual disability. KDM5 proteins can regulate transcription through their histone demethylase activity in addi
Externí odkaz:
https://doaj.org/article/58e77dd544d441039134b2ff7d072bf7
Autor:
Rossella Fioravanti, Veronica Rodriguez, Jonatan Caroli, Ugo Chianese, Rosaria Benedetti, Elisabetta Di Bello, Beatrice Noce, Clemens Zwergel, Davide Corinti, Dolores Viña, Lucia Altucci, Andrea Mattevi, Sergio Valente, Antonello Mai
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 973-985 (2022)
As regioisomers/bioisosteres of 1a, a 4-phenylbenzamide tranylcypromine (TCP) derivative previously disclosed by us, we report here the synthesis and biological evaluation of some (hetero)arylbenzoylamino TCP derivatives 1b-6, in which the 4-phenyl m
Externí odkaz:
https://doaj.org/article/93fcd4f9950b49e69e71b43501b4fcde
Autor:
Junting JIA, Bingxian CHEN, Rouxian WU, Zhangyan DAI, Mingsheng ZHONG, Hao XIE, Shuangxing LIU, Jun LIU
Publikováno v:
Guangdong nongye kexue, Vol 49, Iss 11, Pp 152-161 (2022)
【Objective】A novel rice histone demethylase gene OsJMJ719 was cloned. The expression pattern of this gene under abiotic stress was analyzed to provide theoretical basis for exploring the function of OsJMJ719 in response to abiotic stress.【Metho
Externí odkaz:
https://doaj.org/article/6ff7473747444a6889c3ed2f35103ab6