Zobrazeno 1 - 10
of 485
pro vyhledávání: '"Histone deacetylase 3"'
Autor:
Rami A. Shahror, Esraa Shosha, Carol Morris, Melissa Wild, Shengyu Mu, Gabor Csanyi, Marjan Boerma, Nancy J. Rusch, Abdelrahman Y. Fouda
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Ischemia-induced retinopathy is a hallmark finding of common visual disorders including diabetic retinopathy (DR) and central retinal artery and vein occlusions. Treatments for ischemic retinopathies fail to improve clinical outcomes and the
Externí odkaz:
https://doaj.org/article/2e407af8ac314c83a3be54573247bc0d
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Acute lung injury (ALI) and its severe counterpart, acute respiratory distress syndrome (ARDS), are critical respiratory conditions with high mortality rates due primarily to acute and intense pulmonary inflammation. Despite significant research adva
Externí odkaz:
https://doaj.org/article/bcd98de263b34d1bbd6293ca7bcc9c25
Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Histone deacetylase 3 (HDAC3) is a member of the histone deacetylase family that has emerged as a crucial target in the quest for novel therapeutic interventions against various complex diseases, including cancer. The repositioning of FDA-approved dr
Externí odkaz:
https://doaj.org/article/820cf28df5b64e5da931bebef58d0fbd
Autor:
Chad W. Smies, Lauren Bellfy, Destiny S. Wright, Sofia G. Bennetts, Mark W. Urban, Chad A. Brunswick, Guanhua Shu, Janine L. Kwapis
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Long-term memories are not stored in a stable state but must be flexible and dynamic to maintain relevance in response to new information. Existing memories are thought to be updated through the process of reconsolidation, in which memory retrieval i
Externí odkaz:
https://doaj.org/article/80d8fea3e80947a3ad8a179ee76cb898
Publikováno v:
eLife, Vol 12 (2023)
Dendritic cells (DCs), the key antigen-presenting cells, are primary regulators of immune responses. Transcriptional regulation of DC development had been one of the major research interests in DC biology; however, the epigenetic regulatory mechanism
Externí odkaz:
https://doaj.org/article/7d68171aa019469cafa4ec9d6adf96f7
Downregulated HDAC3 or up-regulated microRNA-296-5p alleviates diabetic retinopathy in a mouse model
Publikováno v:
Regenerative Therapy, Vol 21, Iss , Pp 1-8 (2022)
Objective: It has been demonstrated the efficacy of histone deacetylase 3 (HDAC3) in diabetes. Nevertheless, the function of HDAC3 in diabetic retinopathy (DR) remained largely obscure. Here, we investigated the HDAC3 effects in DR mice through the m
Externí odkaz:
https://doaj.org/article/c7595ca4b67a42b3adbca8a1b3be930a
Publikováno v:
Redox Biology, Vol 63, Iss , Pp 102746- (2023)
Sepsis is one common cause of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), which is closely associated with high mortality in intensive care units (ICU). Histone deacetylase 3 (HDAC3) serves as an important epigenetic modif
Externí odkaz:
https://doaj.org/article/cfa6e5ca36c844d993503902d74c7792
Akademický článek
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Akademický článek
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