Zobrazeno 1 - 10
of 1 356
pro vyhledávání: '"Histone chaperone"'
Autor:
Sruthy Manuraj Rajam, Pallavi Chinnu Varghese, Mayur Balkrishna Shirude, Khaja Mohieddin Syed, Anjali Devarajan, Kathiresan Natarajan, Debasree Dutta
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 3, Pp 151439- (2024)
Our recent studies revealed the role of mouse Aprataxin PNK-like Factor (APLF) in development. Nevertheless, the comprehensive characterization of mouse APLF remains entirely unexplored. Based on domain deletion studies, here we report that mouse APL
Externí odkaz:
https://doaj.org/article/9b8856a6571149efa42d74c670f49588
Autor:
Fouad Ouasti, Maxime Audin, Karine Fréon, Jean-Pierre Quivy, Mehdi Tachekort, Elizabeth Cesard, Aurélien Thureau, Virginie Ropars, Paloma Fernández Varela, Gwenaelle Moal, Ibrahim Soumana-Amadou, Aleksandra Uryga, Pierre Legrand, Jessica Andreani, Raphaël Guerois, Geneviève Almouzni, Sarah Lambert, Francoise Ochsenbein
Publikováno v:
eLife, Vol 12 (2024)
Genome and epigenome integrity in eukaryotes depends on the proper coupling of histone deposition with DNA synthesis. This process relies on the evolutionary conserved histone chaperone CAF-1 for which the links between structure and functions are st
Externí odkaz:
https://doaj.org/article/e4eaadc73ce04cfaa4c47752fee0fda9
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Background The FACT complex is a conserved histone chaperone with critical roles in transcription and histone deposition. FACT is essential in pluripotent and cancer cells, but otherwise dispensable for most mammalian cell types. FACT deleti
Externí odkaz:
https://doaj.org/article/2ddd6cc9e42b4eb3aa55ead56ee9e97d
Autor:
Jiho Lee, Xiucong Bao
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6403 (2024)
Histone chaperones are integral to chromatin dynamics, facilitating the assembly and disassembly of nucleosomes, thereby playing a crucial role in regulating gene expression and maintaining genomic stability. Moreover, they prevent aberrant histone i
Externí odkaz:
https://doaj.org/article/0ef94629514242c387ab6d6c9f94251c
Publikováno v:
mBio, Vol 15, Iss 1 (2024)
ABSTRACTThe highly conserved eukaryotic histone chaperone ASF1 is involved in the assembly and disassembly of nucleosomes during transcription, DNA replication, and repair. It was the first chaperone discovered to be involved in all three of these pr
Externí odkaz:
https://doaj.org/article/88a05fb2bc334b8dbd8e925f8e34609f
Autor:
Maria Ignatyeva, Abdul Kareem Mohideen Patel, Abdulkhaleg Ibrahim, Raed S. Albiheyri, Ali T. Zari, Ahmed Bahieldin, Christian Bronner, Jamal S. M. Sabir, Ali Hamiche
Publikováno v:
Cells, Vol 13, Iss 3, p 273 (2024)
HIRIP3 is a mammalian protein homologous to the yeast H2A.Z deposition chaperone Chz1. However, the structural basis underlying Chz’s binding preference for H2A.Z over H2A, as well as the mechanism through which Chz1 modulates histone deposition or
Externí odkaz:
https://doaj.org/article/b00a62c5ecd14706abc94bba54086769
Autor:
Ruben Rosas, Rhiannon R Aguilar, Nina Arslanovic, Anna Seck, Duncan J Smith, Jessica K Tyler, Mair EA Churchill
Publikováno v:
eLife, Vol 12 (2023)
The histone chaperone chromatin assembly factor 1 (CAF-1) deposits two nascent histone H3/H4 dimers onto newly replicated DNA forming the central core of the nucleosome known as the tetrasome. How CAF-1 ensures there is sufficient space for the assem
Externí odkaz:
https://doaj.org/article/62285cb04994432d93263bf4766c7de6
Publikováno v:
Cells, Vol 12, Iss 24, p 2828 (2023)
Histones and DNA associate to form the nucleosomes of eukaryotic chromatin. Chromatin assembly factor 1 (CAF-1) complex and histone regulatory protein A (HIRA) complex mediate replication-couple (RC) and replication-independent (RI) nucleosome assemb
Externí odkaz:
https://doaj.org/article/00a934675b0d46cd9566f367608ae0e3
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Akademický článek
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