Zobrazeno 1 - 10
of 990
pro vyhledávání: '"Histone H3 acetylation"'
Autor:
Rongfang Wei, Yan Zhu, Yuanjiao Zhang, Wene Zhao, Xichao Yu, Ling Wang, Chunyan Gu, Xiaosong Gu, Ye Yang
Publikováno v:
Cancer Communications, Vol 42, Iss 11, Pp 1185-1206 (2022)
Abstract Background Multiple myeloma (MM) is the second most common hematological malignancy. An overwhelming majority of patients with MM progress to serious osteolytic bone disease. Aminoacyl‐tRNA synthetase‐interacting multifunctional protein
Externí odkaz:
https://doaj.org/article/cab338c2d42d41d68c8c157ef714cc0c
Akademický článek
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Autor:
Smita S. Ghare, Benjamin T. Charpentier, Dushan T. Ghooray, Jingwen Zhang, Manicka V. Vadhanam, Sreelatha Reddy, Swati Joshi-Barve, Craig J. McClain, Shirish S. Barve
Publikováno v:
Nutrients, Vol 15, Iss 20, p 4397 (2023)
Purpose: Chemokine-driven leukocyte infiltration and sustained inflammation contribute to alcohol-associated liver disease (ALD). Elevated hepatic CCL2 expression, seen in ALD, is associated with disease severity. However, mechanisms of CCL2 regulati
Externí odkaz:
https://doaj.org/article/b36e71d2afe642ff9f75b29c63bbb365
Akademický článek
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Autor:
Yanfei Wang, Can Hou, Jonathan Wisler, Kanhaiya Singh, Chao Wu, Zhiguo Xie, Qianjin Lu, Zhiguang Zhou
Publikováno v:
Journal of Diabetes Investigation, Vol 10, Iss 1, Pp 51-61 (2019)
Abstract Aims/Introduction Genetic and epigenetic mechanisms have been implicated in the pathogenesis of type 1 diabetes, and histone acetylation is an epigenetic modification pattern that activates gene transcription. However, the genome‐wide hist
Externí odkaz:
https://doaj.org/article/05076a5b0d114f9381f6af9760b437d4
Autor:
John Wesley Pike, Mark B. Meyer
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12352 (2021)
Recent studies of transcription have revealed an advanced set of overarching principles that govern vitamin D action on a genome-wide scale. These tenets of vitamin D transcription have emerged as a result of the application of now well-established t
Externí odkaz:
https://doaj.org/article/810f5b77afbb494fa7ffe7e5a8e2bb31
Autor:
Shivashankar Damodaran, Nathan Damaschke, Joseph Gawdzik, Bing Yang, Cedric Shi, Glenn O. Allen, Wei Huang, John Denu, David Jarrard
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-8 (2017)
Abstract Background Histones undergo extensive post-translational modifications and this epigenetic regulation plays an important role in modulating transcriptional programs capable of driving cancer progression. Acetylation of histone H3K18, associa
Externí odkaz:
https://doaj.org/article/6a669ba273564161b5fa1bac5eec0da3
Akademický článek
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Autor:
Michael Kyba, Christian A Palumbo, Kevin A Knights, Micah D. Gearhart, Darko Bosnakovski, Hannah J. Maple, Erik A. Toso, Natalie C Xu, Mark S Cooper, Graham P. Marsh, Elizabeth T. Ener
Publikováno v:
Oncogenesis, Vol 10, Iss 10, Pp 1-11 (2021)
Oncogenesis
Oncogenesis
CIC-DUX4 sarcoma (CDS) is a highly aggressive and metastatic small round type of predominantly pediatric sarcoma driven by a fusion oncoprotein comprising the transcriptional repressor Capicua (CIC) fused to the C-terminal transcriptional activation
Autor:
Daniela Pochmann, Ivy Reichert Vital da Silva, Rafael Perin Arpini, Caroline Dani, Viviane Rostirola Elsner, Víctor García Gimenez, Rafael Sánchez Borrego, Mariana Sponchiado Arpini
Publikováno v:
Journal of Plastic, Reconstructive & Aesthetic Surgery. 74:2392-2442
Non-invasive radiofrequency acts through an electromagnetic field that generates a thermal effect on adipose tissue without contact with the skin. The temperature in the subcutaneous reaches between 44°C to 45°C, which after 45 minutes of intervent