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pro vyhledávání: '"Histone Acetyltransferases/immunology/metabolism"'
Autor:
Andreas Trumpp, Carla Sawan, Rabih Murr, Zhao-Qi Wang, Zdenko Herceg, Gabriela M. Oser, Joanna I. Loizou, Vivek Shukla
Publikováno v:
Journal of Immunology, Vol. 183, No 10 (2009) pp. 6422-31
The pool of hematopoietic stem/progenitor cells, which provide life-long reconstitution of all hematopoietic lineages, is tightly controlled and regulated by self-renewal and apoptosis. Histone modifiers and chromatin states are believed to govern es