Zobrazeno 1 - 10
of 830
pro vyhledávání: '"Histidine-rich glycoprotein"'
Autor:
Wei Jiang, Yuexin Zhao, Rongrong Liu, Bohao Zhang, Yuhan Xie, Bin Gao, Kaibin Shi, Ming Zou, Dongmei Jia, Jiayue Ding, Xiaowei Hu, Yanli Duan, Ranran Han, DeRen Huang, Luc Van Kaer, Fu-Dong Shi
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2146-2169 (2024)
Abstract Intravenous thrombolysis using recombinant tissue plasminogen activator (tPA) remains the primary treatment for patients with acute ischemic stroke (AIS). However, the mechanism of tPA-related hemorrhagic transformation (HT) remains poorly u
Externí odkaz:
https://doaj.org/article/fd978869bc3f4b6bab4540fa9dcacb34
Autor:
Ryo Muko, Yoshinobu Ojima, Hiroshi Matsuda, Yuko Toishi, Masa-aki Oikawa, Taekyun Shin, Hiroaki Sato, Akane Tanaka
Publikováno v:
Veterinary and Animal Science, Vol 25, Iss , Pp 100361- (2024)
Previously, we demonstrated unique insertion/deletion polymorphisms of equine histidine-rich glycoprotein (eHRG) with five genotypes composed of 45-bp or 90-bp deletions in the histidine-rich region of eHRG in Thoroughbred horses. Although leukocytes
Externí odkaz:
https://doaj.org/article/ee96304ea2ac40d88c3d39f7c772788b
Autor:
Beatrice Foglia, Salvatore Sutti, Stefania Cannito, Chiara Rosso, Marina Maggiora, Alice Casalino, Claudia Bocca, Erica Novo, Francesca Protopapa, Naresh Naik Ramavath, Alessia Provera, Alessandro Gambella, Elisabetta Bugianesi, Frank Tacke, Emanuele Albano, Maurizio Parola
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundMetabolic dysfunction-associated steatotic liver disease (MASLD), previously non-alcoholic fatty liver disease (NAFLD), is a leading cause of chronic liver disease worldwide. In 20%–30% of MASLD patients, the disease progresses to metabol
Externí odkaz:
https://doaj.org/article/d6a5de90512a4675bd04fbf010588c35
Autor:
Kevin H. Toomer, Gloria F. Gerber, Yifan Zhang, Laetitia Daou, Michael Tushek, Jody E. Hooper, Ivo M. B. Francischetti
Publikováno v:
eJHaem, Vol 4, Iss 2, Pp 324-338 (2023)
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection results in coagulation activation although it is usually not associated with consumption coagulopathy. D‐dimers are also commonly elevated despite systemic hypofibr
Externí odkaz:
https://doaj.org/article/6df57bfbd0cd4ecfaec3563339a660f5
Autor:
M. Nishibori
Publikováno v:
Journal of Pharmacological Sciences, Vol 150, Iss 1, Pp 9-20 (2022)
In 2016, sepsis was newly defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis remains one of the crucial medical problems to be solved worldwide. Although the world health organization has made se
Externí odkaz:
https://doaj.org/article/1916ba3215844d908d49ae66507a0a51
Publikováno v:
BMC Anesthesiology, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Decrease in histidine-rich glycoprotein (HRG) was reported as a cause of dysregulation of the coagulation-fibrinolysis and immune systems, leading to multi-organ failure, and it may be a biomarker for sepsis, ventilator-associated
Externí odkaz:
https://doaj.org/article/ff404ee88ef24ca986385ac068eec9fb
Akademický článek
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Publikováno v:
Genes and Diseases, Vol 9, Iss 2, Pp 381-392 (2022)
Histidine-rich glycoprotein (HRGP) is a relatively less known glycoprotein, but it is abundant in plasma with a multidomain structure, which allows it to interact with many ligands and regulate various biological processes. HRGP ligands includes heme
Externí odkaz:
https://doaj.org/article/e8d36474ba444fbc9ae292edd062334a
Autor:
Daisaku Morimoto, Yosuke Washio, Kei Tamai, Takeshi Sato, Tomoka Okamura, Hirokazu Watanabe, Yu Fukushima, Junko Yoshimoto, Misao Kageyama, Kenji Baba, Hirokazu Tsukahara
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 212 (2023)
Histidine-rich glycoprotein (HRG) has been reported to inhibit signaling leading to the release of high mobility group box 1 protein, a damage-associated molecular pattern. The present study aimed to determine the longitudinal change in HRG levels in
Externí odkaz:
https://doaj.org/article/80c936093758403787886bd8eb03580f
Autor:
Malik, Rida A.
Recent studies suggest that factor (F) XII plays a key role in thrombus stabilization and growth but is dispensable for hemostasis. We have previously shown that histidine-rich glycoprotein (HRG), a protein present in platelets and plasma, binds FXII
Externí odkaz:
http://hdl.handle.net/11375/29274