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Akademický článek

A structural analysis of the splice-specific functional impact of the pathogenic familial hemiplegic migraine type 1 S218L mutation on Cav2.1 P/Q-type channel gating

Autor: Anne-Sophie Sack, Gennerick J. Samera, Anna Hissen, Robert J. Wester, Esperanza Garcia, Paul J. Adams, Terrance P. Snutch

Publikováno v: Molecular Brain, Vol 17, Iss 1, Pp 1-19 (2024)

Abstract P/Q-type (Cav2.1) calcium channels mediate Ca2+ influx essential for neuronal excitability and synaptic transmission. The CACNA1A gene, encoding the Cav2.1 pore forming subunit, is highly expressed throughout the mammalian central nervous sy

Externí odkaz: https://doaj.org/article/294512c7b0d148b3890f93e7458aed64

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Akademický článek

Prolonged abdominal pregnancy incidentally discovered during cesarean section: a case report

Autor: Hamidou Soumana Diaouga, Maimouna Chaibou Yacouba, Tidjani Mahamat Hissen, Maina Oumara, Inoussa Daouda Bako, Rahamatou Madeleine Garba, Nafiou Idi, Madi Nayama

Publikováno v: BMC Pregnancy and Childbirth, Vol 24, Iss 1, Pp 1-5 (2024)

Abstract Background Abdominal pregnancy is a rare medical condition that is still missed in developing countries due to inadequate medical facilities. The clinical indicators manifest in various forms and are nonspecific, making it challenging to dia

Externí odkaz: https://doaj.org/article/df332813edc3468aacd49fa27f6d060f

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Akademický článek

Immunonutrition: facilitating mucosal immune response in teleost intestine with amino acids through oxidant-antioxidant balance

Autor: Karina L. Hissen, Wenliang He, Guoyao Wu, Michael F. Criscitiello

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Comparative animal models generate fundamental scientific knowledge of immune responses. However, these studies typically are conducted in mammals because of their biochemical and physiological similarity to humans. Presently, there has been an inter

Externí odkaz: https://doaj.org/article/2821550cf8c845cb8c3c70b8af96fef0

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Akademický článek

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Akademický článek

Sympathetic and hemodynamic responses to exercise in heart failure with preserved ejection fraction

Autor: Kazumasa Manabe, Andrew W. D’Souza, Takuro Washio, Ryosuke Takeda, Sarah L. Hissen, John D. Akins, Qi Fu

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 10 (2023)

Excessive sympathetic activity during exercise causes heightened peripheral vasoconstriction, which can reduce oxygen delivery to active muscles, resulting in exercise intolerance. Although both patients suffering from heart failure with preserved an

Externí odkaz: https://doaj.org/article/7372f18ce087499bbb83e31123f4b4da

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