Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hishani Prabaharan"'
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :379-389
The syntheses of bis-spiroacetals 25a, 25c and 40 which constitute the central framework of the polyether antibiotic CP44,161 4, are described. The tricyclic bis-spiroacetal ring is formed by oxidative cyclisation of hydroxyspiroacetal 9 which in tur
Publikováno v:
Tetrahedron. 56:1937-1992
Publikováno v:
Synlett. 1999:295-298
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2795-2801
The synthesis of tetracyclic polyethers 16 and 17, which are closely related to the polyether antibiotics epi-17-deoxy-(O-8)-salinomycin 3 and CP44,161 4, is described. The key step involved Barbier–Grignard addition of bromide 8 to bis-spiroacetal
Publikováno v:
Tetrahedron. 54:2113-2128
The work described herein provides a model system for appendage of the E ring of epi-17-deoxy-(O-8)-salinomycin3 onto bis-spiroacetal aldehyde 6. The conversion of aldehyde 7 to bicyclic ether 8 via silver assisted ring expansion of the mesylate deri
Publikováno v:
ChemInform. 27
The first syntheses of the pyranonaphthoquinone antibiotics 5-epi-arizonin B1 16, 5-epi-arizonin C1 15 and arizonin C1 3 are described. The key steps involve addition of 2-trimethylsilyloxyfuran 12 to the 2-acetylnaphthoquinone 11 affording the adduc
Publikováno v:
ChemInform. 28
The preparation of 8-bromokalafungin (20) which is a key intermediate for the synthesis of C-glycoside containing pyranonaphthoquinone antibiotics related to medermycin (6) is described. Although attempts to selectively monobrominate kalafungin (1) a
Publikováno v:
ChemInform. 31
The synthesis of tetracyclic polyethers 16 and 17, which are closely related to the polyether antibiotics epi-17-deoxy-(O-8)-salinomycin 3 and CP44,161 4, is described. The key step involved Barbier–Grignard addition of bromide 8 to bis-spiroacetal
Publikováno v:
ChemInform. 31
Publikováno v:
ChemInform. 32
The syntheses of bis-spiroacetals 25a, 25c and 40 which constitute the central framework of the polyether antibiotic CP44,161 4, are described. The tricyclic bis-spiroacetal ring is formed by oxidative cyclisation of hydroxyspiroacetal 9 which in tur