Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Hisham Abdel-Azim"'
Autor:
Huynh Cao, Jeffrey Xiao, David J. Baylink, Vinh Nguyen, Nathan Shim, Jae Lee, Dave J. R. Mallari, Samiksha Wasnik, Saied Mirshahidi, Chien-Shing Chen, Hisham Abdel-Azim, Mark E. Reeves, Yi Xu
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2250 (2024)
Background: T-cell-based adoptive cell therapies have emerged at the forefront of cancer immunotherapies; however, failed long-term survival and inevitable exhaustion of transplanted T lymphocytes in vivo limits clinical efficacy. Leukemia blasts pos
Externí odkaz:
https://doaj.org/article/ebb1a91ed9ef452bb180d39522240859
Autor:
Dristhi Ragoonanan, Hisham Abdel-Azim, Aditya Sharma, Saleh Bhar, Jennifer McArthur, Renee Madden, April Rahrig, Rajinder Bajwa, Jian Wang, Victoria Sun, Mariah Wright, Rebekah Lassiter, Basirat Shoberu, Jitesh Kawedia, Sajad Jawad Khazal, Kris Michael Mahadeo
Publikováno v:
The Lancet Regional Health. Americas, Vol 33, Iss , Pp 100728- (2024)
Summary: Background: Sinusoidal obstruction syndrome is a potentially fatal complication following hematopoietic cell transplantation, high-intensity chemotherapies and increasingly seen with calicheamicin based leukemia therapies. Paediatric specifi
Externí odkaz:
https://doaj.org/article/a6460f7245804d2981330d6fd03ab969
Autor:
Dristhi Ragoonanan, Saleh Bhar, Gopi Mohan, Fernando Beltramo, Sajad J. Khazal, Caitlin Hurley, Clark Andersen, Steven Margossian, Sattva S. Neelapu, Elizabeth Shpall, Cristina Gutierrez, Priti Tewari, Basirat Shoberu, Aimee Talleur, David McCall, Cesar Nunez, Branko Cuglievan, Francesco Paolo Tambaro, Demetrios Petropoulos, Hisham Abdel-Azim, Kris M. Mahadeo
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Tisagenlecleucel is associated with remarkable outcomes in treating patients up to the age of 25 years with refractory B-cell acute lymphoblastic leukemia (ALL). Yet, due to unique and potentially life-threatening complications, access remains limite
Externí odkaz:
https://doaj.org/article/71b4d203dce3414a8d445a994168fe5a
Autor:
Yongsheng Ruan, Hye Na Kim, Heather A. Ogana, Zesheng Wan, Samantha Hurwitz, Cydney Nichols, Nour Abdel-Azim, Ariana Coba, Seyoung Seo, Yong-Hwee Eddie Loh, Eun Ji Gang, Hisham Abdel-Azim, Chih-Lin Hsieh, Michael R. Lieber, Chintan Parekh, Dhananjaya Pal, Deepa Bhojwani, Donald L. Durden, Yong-Mi Kim
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The PI3K/Akt pathway—and in particular PI3Kδ—is known for its role in drug resistant B-cell acute lymphoblastic leukemia (B-ALL) and it is often upregulated in refractory or relapsed B-ALL. Myc proteins are transcription factors responsible for
Externí odkaz:
https://doaj.org/article/9d2a16f695cc4722b8574521dd391e56
Autor:
Aleksandr Lazaryan, Michelle Dolan, Mei-Jie Zhang, Hai-Lin Wang, Mohamed A. Kharfan-Dabaja, David I. Marks, Nelli Bejanyan, Edward Copelan, Navneet S. Majhail, Edmund K. Waller, Nelson Chao, Tim Prestidge, Taiga Nishihori, Partow Kebriaei, Yoshihiro Inamoto, Betty Hamilton, Shahrukh K. Hashmi, Rammurti T. Kamble, Ulrike Bacher, Gerhard C. Hildebrandt, Patrick J. Stiff, Joseph McGuirk, Ibrahim Aldoss, Amer M. Beitinjaneh, Lori Muffly, Ravi Vij, Richard F. Olsson, Michael Byrne, Kirk R. Schultz, Mahmoud Aljurf, Matthew Seftel, Mary Lynn Savoie, Bipin N. Savani, Leo F. Verdonck, Mitchell S. Cairo, Nasheed Hossain, Vijaya Raj Bhatt, Haydar A. Frangoul, Hisham Abdel-Azim, Monzr Al Malki, Reinhold Munker, David Rizzieri, Nandita Khera, Ryotaro Nakamura, Olle Ringdén, Marjolein van der Poel, Hemant S. Murthy, Hongtao Liu, Shahram Mori, Satiro De Oliveira, Javier Bolaños-Meade, Mahmoud Elsawy, Pere Barba, Sunita Nathan, Biju George, Attaphol Pawarode, Michael Grunwald, Vaibhav Agrawal, Youjin Wang, Amer Assal, Paul Castillo Caro, Yachiyo Kuwatsuka, Sachiko Seo, Celalettin Ustun, Ioannis Politikos, Hillard M. Lazarus, Wael Saber, Brenda M. Sandmaier, Marcos De Lima, Mark Litzow, Veronika Bachanova, Daniel Weisdorf
Publikováno v:
Haematologica, Vol 106, Iss 8 (2021)
Externí odkaz:
https://doaj.org/article/5f4f65fecf5144b8af57be068ff20e60
Autor:
Nelli Bejanyan, Soyoung Kim, Kyle M. Hebert, Natasha Kekre, Hisham Abdel-Azim, Ibrahim Ahmed, Mahmoud Aljurf, Sherif M. Badawy, Amer Beitinjaneh, Jaap Jan Boelens, Miguel Angel Diaz, Christopher C. Dvorak, Shahinaz Gadalla, James Gajewski, Robert Peter Gale, Siddhartha Ganguly, Andrew R. Gennery, Biju George, Usama Gergis, David Gómez-Almaguer, Marta Gonzalez Vicent, Hasan Hashem, Rammurti T. Kamble, Kimberly A. Kasow, Hillard M. Lazarus, Vikram Mathews, Paul J. Orchard, Michael Pulsipher, Olle Ringden, Kirk Schultz, Pierre Teira, Ann E. Woolfrey, Blachy Dávila Saldaña, Bipin Savani, Jacek Winiarski, Jean Yared, Daniel J. Weisdorf, Joseph H. Antin, Mary Eapen
Publikováno v:
Blood Advances, Vol 3, Iss 20, Pp 3123-3131 (2019)
Abstract: Allogeneic bone marrow transplantation (BMT) is curative therapy for the treatment of patients with severe aplastic anemia (SAA). However, several conditioning regimens can be used for BMT. We evaluated transplant conditioning regimens for
Externí odkaz:
https://doaj.org/article/5355366127ff44c8b0ec931af3a7f734
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0258140 (2021)
The bone marrow is a frequent location of primary relapse after conventional cytotoxic drug treatment of human B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Because stromal cells have a major role in promoting chemotherapy resistance, they
Externí odkaz:
https://doaj.org/article/fb726bee2dec474d82344c0560cf0c59
Autor:
Christopher E. Dandoy, Stella M. Davies, Kwang Woo Ahn, Yizeng He, Anders E. Kolb, John Levine, Stephanie Bo-Subait, Hisham Abdel-Azim, Neel Bhatt, Joseph Chewning, Shahinaz Gadalla, Nicholas Gloude, Robert Hayashi, Nahal R. Lalefar, Jason Law, Margaret MacMillan, Tracy O'Brien, Timothy Prestidge, Akshay Sharma, Peter Shaw, Lena Winestone, Mary Eapen
Publikováno v:
Haematologica, Vol 106, Iss 7 (2020)
With limited data comparing hematopoietic cell transplant outcomes between myeloablative total body irradiation (TBI) containing and non-TBI regimens in children with de novo acute myeloid leukemia, the aim of this study was to compare transplant-out
Externí odkaz:
https://doaj.org/article/5e1ad268425b42f087f5d0fcff1b7103
Autor:
Aleksandr Lazaryan, Michelle Dolan, Mei-Jie Zhang, Hai-Lin Wang, Mohamed A. Kharfan-Dabaja, David I. Marks, Nelli Bejanyan, Edward Copelan, Navneet S. Majhail, Edmund K. Waller, Nelson Chao, Tim Prestidge, Taiga Nishihori, Partow Kebriaei, Yoshihiro Inamoto, Betty Hamilton, Shahrukh K. Hashmi, Rammurti T. Kamble, Ulrike Bacher, Gerhard C. Hildebrandt, Patrick J. Stiff, Joseph McGuirk, Ibrahim Aldoss, Amer M. Beitinjaneh, Lori Muffly, Ravi Vij, Richard F. Olsson, Michael Byrne, Kirk R. Schultz, Mahmoud Aljurf, Matthew Seftel, Mary Lynn Savoie, Bipin N. Savani, Leo F. Verdonck, Mitchell S. Cairo, Nasheed Hossain, Vijaya Raj Bhatt, Haydar A. Frangoul, Hisham Abdel-Azim, Monzr Al Malki, Reinhold Munker, David Rizzieri, Nandita Khera, Ryotaro Nakamura, Olle Ringdén, Marjolein van der Poel, Hemant S. Murthy, Hongtao Liu, Shahram Mori, Satiro De Oliveira, Javier Bolaños-Meade, Mahmoud Elsawy, Pere Barba, Sunita Nathan, Biju George, Attaphol Pawarode, Michael Grunwald, Vaibhav Agrawal, Youjin Wang, Amer Assal, Paul Castillo Caro, Yachiyo Kuwatsuka, Sachiko Seo, Celalettin Ustun, Ioannis Politikos, Hillard M. Lazarus, Wael Saber, Brenda M. Sandmaier, Marcos De Lima, Mark Litzow, Veronika Bachanova, Daniel Weisdorf, Acute Leukemia Committee of the CIBMTR
Publikováno v:
Haematologica, Vol 105, Iss 5 (2020)
Cytogenetic risk stratification at diagnosis has long been one of the most useful tools to assess prognosis in acute lymphoblastic leukemia (ALL). To examine the prognostic impact of cytogenetic abnormalities on outcomes after allogeneic hematopoieti
Externí odkaz:
https://doaj.org/article/0a9dd539d4d7436794f9d085bd9329f3
Autor:
Helicia Paz, Eun Ji Joo, Chih-Hsing Chou, Fei Fei, Kevin H. Mayo, Hisham Abdel-Azim, Haike Ghazarian, John Groffen, Nora Heisterkamp
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-15 (2018)
Abstract Background Drug resistance of B-cell precursor acute lymphoblastic leukemia (BP-ALL) cells is conferred by both intrinsic and extrinsic factors, which could be targeted to promote chemo-sensitization. Our previous studies showed that Galecti
Externí odkaz:
https://doaj.org/article/473c69e2456944a39311ccf9e58ab06e