Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Hisayoshi Hashimoto"'
Autor:
Katja Sonntag, Hisayoshi Hashimoto, Matthias Eyrich, Moritz Menzel, Max Schubach, Dennis Döcker, Florian Battke, Carolina Courage, Helmut Lambertz, Rupert Handgretinger, Saskia Biskup, Karin Schilbach
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-13 (2018)
Abstract Background Cancer vaccines can effectively establish clinically relevant tumor immunity. Novel sequencing approaches rapidly identify the mutational fingerprint of tumors, thus allowing to generate personalized tumor vaccines within a few we
Externí odkaz:
https://doaj.org/article/6a7d75ac51884234b96f8df8645ef5f5
Autor:
Hans-Jörg Bühring, Karin Schilbach, Jakob Kressin, Rupert Handgretinger, Patrick Kasteleiner, Hisayoshi Hashimoto, Friederike Müller
Publikováno v:
Bone Marrow Transplantation
Detrimental graft-versus-host disease (GVHD) still remains a major cause of death in hematopoietic stem cell transplantation (HSCT). The recently explored depletion of naive cells from mobilized grafts (CD45RA depletion) has shown considerable promis
Autor:
Hisayoshi, Hashimoto, Derya, Güngör, Naomi, Krickeberg, Johanna, Schmitt, Larissa, Doll, Marina, Schmidt, Sabine, Schleicher, Elvira, Criado-Moronati, Karin, Schilbach
Publikováno v:
Leukemia research. 117
Cancer testis antigen PRAME is over-expressed in a variety of malignant cells but is not or minimally expressed in normal non-germ line cells. Adoptive transfer of PRAME-specific T cells is thus under investigation in clinical trials as an innovative
Autor:
Simon Mingram, Naomi Krickeberg, Gabrielle M. Siegers, Carlotta Kaißer, Karin Schilbach, Janika Kind, Hisayoshi Hashimoto
Publikováno v:
Cancer Immunology, Immunotherapy. 69:593-610
Despite recent progress in the understanding of γδ T cells’ roles and functions, their interaction with αβ T cells still remains to be elucidated. In this study, we sought to clarify what precisely endows peripheral Vδ2+ T cells with immunosup
Autor:
Kenta Narumi, Reina Miyakawa, Marina Henmi, Teruhiko Yoshida, Kazunori Aoki, Ryosuke Ueda, Nobuyoshi Hiraoka, Hisayoshi Hashimoto, Chihiro Shibasaki, Yukihiro Mizoguchi
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports
Scientific Reports
An anti-glucocorticoid induced TNF receptor (GITR) agonistic antibody (Ab) induces an antitumor immunity with both stimulation of effector T cells and inhibition of regulatory T cell activity. To enhance GITR Ab-mediated tumor immunity, we focused on
Autor:
Hisayoshi Hashimoto, Derya Güngör, Naomi Krickeberg, Johanna Schmitt, Larissa Doll, Marina Schmidt, Sabine Schleicher, Elvira Criado-Moronati, Karin Schilbach
Publikováno v:
Leukemia Research. 117:106842
Autor:
Susanne Sebens, Markus W. Löffler, Jonas Bochem, Kilian Wistuba-Hamprecht, Christian Peters, Daniela Wesch, Dieter Kabelitz, Paola Nocerino, Hisayoshi Hashimoto, Hans-Heinrich Oberg, Karin Schilbach, Claus Garbe, Christoph Röcken, Shahram Kordasti, Nicola Beucke, Graham Pawelec, Benjamin Weide
Publikováno v:
Beucke, N, Wesch, D, Oberg, H-H, Peters, C, Bochem, J, Weide, B, Garbe, C, Pawelec, G, Sebens, S, Röcken, C, Hashimoto, H, Löffler, M W, Nocerino, P, Kordasti, S, Kabelitz, D, Schilbach, K & Wistuba-Hamprecht, K 2020, ' Pitfalls in the characterization of circulating and tissue-resident human γδ T cells ', Journal of Leukocyte Biology, vol. 107, no. 6, pp. 1097-1105 . https://doi.org/10.1002/JLB.5MA1219-296R
Dissection of the role and function of human γδ T cells and their heterogeneous subsets in cancer, inflammation, and auto-immune diseases is a growing and dynamic research field of increasing interest to the scientific community. Therefore, harmoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d444cda55762b6a1f52d7e4a73f59e59
https://kclpure.kcl.ac.uk/en/publications/2ca0d14b-02dd-4742-922f-b33b5185b0f8
https://kclpure.kcl.ac.uk/en/publications/2ca0d14b-02dd-4742-922f-b33b5185b0f8
Autor:
Hisayoshi Hashimoto, Christian Welker, Sabine Schleicher, Carlotta Kaißer, Karin Schilbach, Naomi Krickeberg
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1, p 130 (2020)
Volume 12
Issue 1
Cancers, Vol 12, Iss 1, p 130 (2020)
Volume 12
Issue 1
Abundant IFN-&gamma
secretion, potent cytotoxicity, and major histocompatibility complex-independent targeting of a large spectrum of tumors make &gamma
&delta
T cells attractive candidates for cancer immunotherapy. Upon tumor recognit
secretion, potent cytotoxicity, and major histocompatibility complex-independent targeting of a large spectrum of tumors make &gamma
&delta
T cells attractive candidates for cancer immunotherapy. Upon tumor recognit
Publikováno v:
Immunologic Research. 66:79-86
Increased numbers of CD8+CD28neg. T cells have been detected in the peripheral blood of patients with several types of malignancies. However, the role of these cells in anticancer immunity are not yet clear and CD8+CD28neg. T cells are a controversia
Autor:
Karin, Schilbach, Naomi, Krickeberg, Carlotta, Kaißer, Simon, Mingram, Janika, Kind, Gabrielle M, Siegers, Hisayoshi, Hashimoto
Publikováno v:
Cancer Immunology, Immunotherapy
Despite recent progress in the understanding of γδ T cells’ roles and functions, their interaction with αβ T cells still remains to be elucidated. In this study, we sought to clarify what precisely endows peripheral Vδ2+ T cells with immunosup