Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hisayo Nishiura"'
Autor:
Tsutomu Chiba, Satoru Iwamoto, Ryutaro Maruoka, Masahiro Kido, Norihiko Watanabe, Hisayo Nishiura, Aki Ikeda, Nobuhiro Aoki
Publikováno v:
Hepatology. 60:224-236
Clinical manifestations of autoimmune hepatitis (AIH) range from mild chronic to acute, sometimes fulminant hepatitis. However, it is unknown how the progression to fatal hepatitis occurs. We developed a mouse model of fatal AIH by inducing a concurr
Autor:
Satoru Iwamoto, Aki Ikeda, Hisayo Nishiura, Tsutomu Chiba, Ryutaro Maruoka, Masahiro Kido, Nobuhiro Aoki, Norihiko Watanabe
Publikováno v:
Journal of Gastroenterology and Hepatology. 28:982-991
Background and Aim Autoimmune gastritis (AIG), an organ-specific autoimmune disease, is accompanied by achlorhydria, pernicious anemia, gastric carcinoid tumors, and gastric cancer. Patients with AIG initially respond to corticosteroids but have a gr
Autor:
Satoru Iwamoto, Hisayo Nishiura, Masahiro Kido, Ryutaro Maruoka, Tsutomu Chiba, Taku Okazaki, Nobuhiro Aoki, Norihiko Watanabe, Aki Ikeda
Publikováno v:
Clinical Immunology. 146:15-25
It is unclear what roles TNF-α has in the development of autoimmune hepatitis (AIH) and whether AIH is responsive to anti-TNF-α. We recently developed a mouse model of fatal AIH that develops in PD-1-deficient mice thymectomized three days after bi
Autor:
Junya Tanaka, Tsutomu Chiba, Hisayo Nishiura, Norihiko Watanabe, Masahiro Kido, Takuji Akamatsu, Kazuyuki Saga
Publikováno v:
Digestive Diseases and Sciences
Purpose Thymic stromal lymphopoietin (TSLP) is released by intestinal epithelial cells (IECs), and TSLP-conditioned dendritic cells appear to be involved in immune homeostasis of intestine and immunoglobulin A (IgA) class-switching in the physiologic
Autor:
Hisayo, Nishiura, Satoru, Iwamoto, Masahiro, Kido, Nobuhiro, Aoki, Ryutaro, Maruoka, Aki, Ikeda, Tsutomu, Chiba, Norihiko, Watanabe
Publikováno v:
Journal of gastroenterology and hepatology. 28(6)
Autoimmune gastritis (AIG), an organ-specific autoimmune disease, is accompanied by achlorhydria, pernicious anemia, gastric carcinoid tumors, and gastric cancer. Patients with AIG initially respond to corticosteroids but have a great potential to re
Autor:
Nobuhiro Aoki, Steven F. Ziegler, Hisayo Nishiura, Norihiko Watanabe, Satoru Iwamoto, Tsutomu Chiba, Ryutaro Maruoka, Masahiro Kido, Aki Ikeda
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 188(1)
Thymic stromal lymphopoietin (TSLP), mainly produced by epithelial cells, activates a variety of cell types, including dendritic cells, mast cells, T cells, and B cells. It is involved in the pathogenesis of allergic inflammation in the lung, skin, a
Autor:
Aki Ikeda, Ryutaro Maruoka, Tsutomu Chiba, Takeshi Azuma, Satoru Iwamoto, Nobuhiro Aoki, Masahiro Kido, Hisayo Nishiura, Norihiko Watanabe
Publikováno v:
Biochemical and biophysical research communications. 412(2)
Cytotoxin-associated gene A (CagA) acts directly on gastric epithelial cells. However, the roles of CagA in host adaptive immunity against Helicobacter pylori (H. pylori) infection are not fully understood. In this study, to investigate the roles of
Autor:
Ryutaro Maruoka, Junya Tanaka, Tsutomu Chiba, Satoru Iwamoto, Hisayo Nishiura, Yoshimasa Tanaka, Takeshi Watanabe, Masahiro Kido, Nobuhiro Aoki, Norihiko Watanabe, Taku Okazaki
Publikováno v:
Gastroenterology. 140(4)
Background & Aims To clarify mechanisms involved in the development of autoimmune hepatitis (AIH), we recently developed a mouse model of spontaneous AIH by inducing a concurrent loss of Foxp3 + regulatory T cells and programmed cell death 1 (PD-1)
Publikováno v:
Gut. 59(5)
Autor:
Satoru Iwamoto, Junya Tanaka, Tsutomu Chiba, Hisayo Nishiura, Nobuhiro Aoki, Masahiro Kido, Norihiko Watanabe
Publikováno v:
Infection and immunity. 78(1)
Helicobacter pylori colonizes the stomach and induces strong, specific local and systemic humoral and cell-mediated immunity, resulting in the development of chronic gastritis in humans. Although H. pylori -induced chronic atrophic gastritis is chara