Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hisato Iriki"'
Autor:
Hisato Iriki, Miho Mukai, Yasuhiko Asahina, Yoko Kubo, Hiromi Ito, Masayuki Amagai, Hayato Takahashi
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-7 (2023)
Abstract Various autoimmune responses increase with age, but the underlying mechanism is not clear. In this study, we used CD4+ T cells expressing a transgenic T cell receptor specific for desmoglein 3 (Dsg3), which is the target antigen of the autoi
Externí odkaz:
https://doaj.org/article/f0c8d2c8aab247a797a9334962683d0b
Autor:
Hisato Iriki, MD, PhD, Noriko Umegaki-Arao, MD, PhD, Risa Kakuta, MD, PhD, Harumi Fujita, PhD, Satomi Aoki, Masayuki Amagai, MD, PhD, Takashi Sasaki, PhD, Yasuo Hamamoto, MD, PhD, Robert Nakayama, MD, PhD, Akiharu Kubo, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 25, Iss , Pp 89-92 (2022)
Externí odkaz:
https://doaj.org/article/6545edb8676945d5a3359f55b8767f6e
Autor:
Risa Fukuda, Takeshi Ouchi, Yasuhiko Asahina, Chihiro Shiiya, Sakiko Takeuchi, Fumiyo Yasuda-Sekiguchi, Hisato Iriki, Michiyoshi Kouno, Shinichi Takahashi, Akiko Tanikawa, Masayuki Amagai, Hayato Takahashi
Publikováno v:
Allergology International, Vol 71, Iss 1, Pp 125-130 (2022)
Background: Natto (fermented soybeans)-induced hypersensitivity is characterized by delayed symptom onset that hampers diagnosis. We aimed to clarify the clinical utility of the basophil activation test (BAT) in the diagnosis of natto-induced hyperse
Externí odkaz:
https://doaj.org/article/76a261f7679d4c778c7bc9f3b905a7f9
Publikováno v:
Journal of Investigative Dermatology. 143:545-553
Publikováno v:
The Journal of Dermatology. 50:112-123
Pemphigus is a life-threatening autoimmune bullous disease mediated by anti-desmoglein IgG autoantibodies. Pemphigus is mainly classified into three subtypes: pemphigus vulgaris, pemphigus foliaceus, and paraneoplastic pemphigus. The pathogenicity of
Autor:
Saeko Takamiyagi, Hisato Iriki, Yasuhiko Asahina, Yuki Furuichi, Takeru Funakoshi, Masataka Ichikawa, Yohei Mikami, Hajime Okita, Tomo Sakiyama, Toyoko Inazumi, Masayuki Amagai, Hayato Takahashi
Publikováno v:
The Journal of Dermatology. 49:796-799
Drug-induced hypersensitivity syndrome (DIHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe drug adverse reaction with skin eruption and visceral organ involvement. The characteristic clinical features of DIHS/DRESS are re
Autor:
Hisashi Nomura, Naoko Wada, Hayato Takahashi, Yuko Kase, Jun Yamagami, Shohei Egami, Hisato Iriki, Miho Mukai, Aki Kamata, Hiromi Ito, Hideki Fujii, Tomoyuki Ishikura, Haruhiko Koseki, Takashi Watanabe, Taketo Yamada, Osamu Ohara, Shigeo Koyasu, Masayuki Amagai
Publikováno v:
The Journal of Immunology. 208:582-593
Pemphigus vulgaris is an autoimmune blistering disease caused by IgG targeting desmoglein 3 (Dsg3), an adhesion molecule of keratinocytes. Anti-Dsg3 IgG production is prevented in healthy individuals, but it is unclear how Dsg3-specific B cells are r
Autor:
Shinichi Takahashi, Michiyoshi Kouno, Sakiko Takeuchi, Chihiro Shiiya, Hisato Iriki, Takeshi Ouchi, Masayuki Amagai, Akiko Tanikawa, Hayato Takahashi, Fumiyo Yasuda-Sekiguchi, Risa Fukuda, Yasuhiko Asahina
Publikováno v:
Allergology International, Vol 71, Iss 1, Pp 125-130 (2022)
Background Natto (fermented soybeans)-induced hypersensitivity is characterized by delayed symptom onset that hampers diagnosis. We aimed to clarify the clinical utility of the basophil activation test (BAT) in the diagnosis of natto-induced hypersen
Publikováno v:
Journal of Dermatological Science. 100:166-174
Background The thymus plays an essential role in removing autoreactive T cells. Autoantigen-expressing thymic epithelial cells (TECs) contribute to the tolerogenic process. The thymus transiently shrinks as an acute thymic involution (ATI) under vari
Autor:
Masayuki Amagai, Osamu Nureki, Naoko Wada, Yutaka Kurebayashi, Jun Yamagami, Akihiko Yoshimura, Shohei Hori, Hisashi Nomura, Hiromi Ito, Miho Mukai, Hiroshi Nishimasu, Takeshi Matsui, Setsuko Mise-Omata, Hayato Takahashi, Aki Kamata, Hisato Iriki
Publikováno v:
Proc Natl Acad Sci U S A
Antigen-specific peripheral tolerance is crucial to prevent the development of organ-specific autoimmunity. However, its function decoupled from thymic tolerance remains unclear. We used desmoglein 3 (Dsg3), a pemphigus antigen expressed in keratinoc