Zobrazeno 1 - 10
of 536
pro vyhledávání: '"Hisato, Kobayashi"'
Autor:
Julien Richard Albert, Toshihiro Kobayashi, Azusa Inoue, Ana Monteagudo-Sánchez, Soichiro Kumamoto, Tomoya Takashima, Asuka Miura, Mami Oikawa, Fumihito Miura, Shuji Takada, Masumi Hirabayashi, Keegan Korthauer, Kazuki Kurimoto, Maxim V. C. Greenberg, Matthew Lorincz, Hisato Kobayashi
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-32 (2023)
Abstract Background Genomic imprinting affects gene expression in a parent-of-origin manner and has a profound impact on complex traits including growth and behavior. While the rat is widely used to model human pathophysiology, few imprinted genes ha
Externí odkaz:
https://doaj.org/article/d2b4346a6d9745bcb4ddefb8b94050fb
Autor:
Haruko Shima, Takumi Kurosawa, Hiroyuki Oikawa, Hisato Kobayashi, Emiri Nishi, Fumito Yamazaki, Kentaro Tomita, Hiroyuki Shimada
Publikováno v:
Case Reports in Oncology, Vol 15, Iss 1, Pp 257-262 (2022)
Cytokine release syndrome (CRS) is one of the major acute complications caused by massive cytokine release after chimeric antigen receptor (CAR) T-cell therapy. Patients with tumor masses were considered at high risk of local CRS induced by the expan
Externí odkaz:
https://doaj.org/article/8476405675ae49ec8f6c9eba53fe76f2
Publikováno v:
Life Science Alliance; Dec2024, Vol. 7 Issue 12, p1-12, 12p
Autor:
Hideki Oe, Hatsumi Yoshiki, Xinmin Zha, Hisato Kobayashi, Yoshitaka Aoki, Hideaki Ito, Osamu Yokoyama
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Anticholinergics, therapeutic agents for overactive bladder, are clinically suggested to reduce urine output. We investigated whether this effect is due to bladder or kidney urine reabsorption. Various solutions were injected into the bladde
Externí odkaz:
https://doaj.org/article/a3eab46303b0499aabd4043c3a0be1ef
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-5 (2021)
Abstract Background The most important target cell of SARS-CoV-2 is Type II pneumocyte which produces and secretes pulmonary surfactant (PS) that prevents alveolar collapse. PS instillation therapy is dramatically effective for infant respiratory dis
Externí odkaz:
https://doaj.org/article/57b7eeee42044c19ae7ea3c89eaf749e
Autor:
Julien Richard Albert, Wan Kin Au Yeung, Keisuke Toriyama, Hisato Kobayashi, Ryutaro Hirasawa, Julie Brind’Amour, Aaron Bogutz, Hiroyuki Sasaki, Matthew Lorincz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The paternal genome in mice undergoes widespread DNA methylation loss post-fertilization. Here, the authors apply allele-specific analysis of WGBS data to show that a number of genomic regions are simultaneously de novo methylated on the paternal gen
Externí odkaz:
https://doaj.org/article/128797e6956e467bae7bb0618d815a9b
Autor:
Aaron B. Bogutz, Julie Brind’Amour, Hisato Kobayashi, Kristoffer N. Jensen, Kazuhiko Nakabayashi, Hiroo Imai, Matthew C. Lorincz, Louis Lefebvre
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Although many species-specific imprinted genes have been identified, how the evolutionary switch from biallelic to imprinted expression occurs is still unknown. Here authors find that lineage-specific ERVs active as oocyte promoters can induce de nov
Externí odkaz:
https://doaj.org/article/23eab72a42084803b96998d94acb4a07
Autor:
Masashi Kurata, Naoko Fujiwara, Ken-ichi Fujita, Yasutaka Yamanaka, Shigeto Seno, Hisato Kobayashi, Yusaku Miyamae, Nobuyuki Takahashi, Yasuyuki Shibuya, Seiji Masuda
Publikováno v:
iScience, Vol 22, Iss , Pp 336-352 (2019)
Summary: Cancer cells often exhibit extreme sensitivity to splicing inhibitors. We identified food-derived flavonoids, apigenin and luteolin, as compounds that modulate mRNA splicing at the genome-wide level, followed by proliferation inhibition. The
Externí odkaz:
https://doaj.org/article/bb48bc0c6e8646a4975788810fc713c3
Autor:
Akiko Yoshida, Ken-ichiro Taoka, Aoi Hosaka, Keisuke Tanaka, Hisato Kobayashi, Tomoaki Muranaka, Kiminori Toyooka, Tokitaka Oyama, Hiroyuki Tsuji
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
Duckweeds (Araceae: Lemnoideae) are aquatic monocotyledonous plants that are characterized by their small size, rapid growth, and wide distribution. Developmental processes regulating the formation of their small leaf-like structures, called fronds,
Externí odkaz:
https://doaj.org/article/796be5de89684e78aa417be3a52baf0a
Autor:
Tomomi Tadokoro, Keisuke Tanaka, Shun Osakabe, Mimoko Kato, Hisato Kobayashi, Brigid L. M. Hogan, Hideki Taniguchi
Publikováno v:
Biology Open, Vol 10, Iss 9 (2021)
The tracheal basal cells (BCs) function as stem cells to maintain the epithelium in steady state and repair it after injury. The airway is surrounded by cartilage ventrolaterally and smooth muscle dorsally. Lineage tracing using Krt5-CreER shows dors
Externí odkaz:
https://doaj.org/article/f087c54da9214d3bb4983904daed81dc