Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Hisataka, Shikama"'
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(3):397-400
Autor:
Yukitaka, Ideyama 1, Masafumi, Kudoh 1, Kyoko, Tanimoto 1, Yoko, Susaki 1, Taiki, Nanya 1, Takahito, Nakahara 1, Hiroko, Ishikawa 1, Takashi, Fujikura 1, Hideyuki, Akaza 2, Hisataka, Shikama 1, *
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(2):213-220
Autor:
Shigeaki Kato, Saya Ito, Takashi Furutani, Hisataka Shikama, Masafumi Kudoh, Masahiko Tanabe, Ken-ichi Takeyama, Hiroshi Koutoku, Masayuki Shibasaki, Eriko Suzuki, Nobuaki Taniguchi
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 315:545-552
Androgen receptor (AR) plays key roles in various biological events, including pathological processes such as prostate cancer, androgen-insensitive syndrome, and spinal and bulbar muscular atrophy (SBMA). SBMA is caused by mutation of the expanded po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7527af05f2a568df2bffea32f253b351
https://doi.org/10.1124/jpet.105.087643
https://doi.org/10.1124/jpet.105.087643
Macrophage-derived lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed Tg rabbits
Autor:
Jingyan Liang, Masatoshi Morimoto, Teruo Watanabe, Jianglin Fan, Nobuhiro Yamada, Shuji Kitajima, Huijun Sun, Xiaofei Wang, Hisataka Shikama, Tomonari Koike, Tomonaga Ichikawa
Publikováno v:
Atherosclerosis. 179:87-95
Lipoprotein lipase (LPL) produced by macrophages is upregulated in the atherosclerotic lesions; however, it is not fully understood whether increased macrophage-derived LPL is pro-atherogenic. To examine the hypothesis that macrophage-derived LPL in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328a06fe71f48e78a00408a188033543
https://doi.org/10.1016/j.atherosclerosis.2004.10.044
https://doi.org/10.1016/j.atherosclerosis.2004.10.044
Autor:
Takashi Miyauchi, Katsutoshi Goto, Satoshi Sakai, Masanao Sanagi, Katsumi Sudoh, Iwao Yamaguchi, Motoyuki Iemitsu, Akira Fujimori, Hironori Yuyama, Hisataka Shikama
Publikováno v:
Journal of Cardiovascular Pharmacology. 44:S354-S357
The effects of the novel, selective endothelin-A (ET A ) receptor antagonist YM598 on both-side heart failure were investigated. Right-side heart failure secondary to pulmonary hypertension was produced by a single subcutaneous injection of 60 mg/kg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697396988cc5876d2352cbeaaebf9a83
https://doi.org/10.1097/01.fjc.0000166304.40937.0b
https://doi.org/10.1097/01.fjc.0000166304.40937.0b
Autor:
Tomonari Koike, Tomonaga Ichikawa, Shuji Kitajima, Teruo Watanabe, Masatoshi Morimoto, Jianglin Fan, Xiaofei Wang, Hisataka Shikama, Huijun Sun, Yasuyuki Sasaguri, Jingyan Liang
Publikováno v:
The American Journal of Pathology. 165:1375-1383
Increased proteolytic activity of matrix metalloproteinases (MMPs) may promote articular destruction such as occurs in rheumatoid arthritis and osteoarthritis. Recently, we reported that synovial tissue and fluid obtained from patients with rheumatoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77e278aeaf4525a8d37f88e8a4e3520f
https://doi.org/10.1016/s0002-9440(10)63395-0
https://doi.org/10.1016/s0002-9440(10)63395-0
Autor:
Eiji Kurosaki, Masayuki Shibasaki, Akiyoshi Shimaya, Kazuhiro Momose, Hisataka Shikama, Takayuki Suzuki, Ryosuke Nakano
Publikováno v:
European Journal of Pharmacology. 468:151-158
Using a glucose clamp, we had shown that YM440, ( Z )-1,4-bis{4-[(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)methyl]phenoxy}but-2-ene, reduced the increased hepatic glucose output in obese Zucker rats. We further examined effects of YM440 on 14 C-incorporati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18253fd4bcf7238eeb6852521df3e8e2
https://doi.org/10.1016/s0014-2999(03)01670-4
https://doi.org/10.1016/s0014-2999(03)01670-4
Publikováno v:
British Journal of Pharmacology. 139:140-146
To better understand how it decreases plasma cholesterol and triglyceride levels, we evaluated the effect of (E)-2-[2-fluoro-2-(quinuclidin-3-ylidene)ethoxy]-9H-carbazole monohydrochloride(YM-53601) on lipogenic biosynthesis in the liver and lipid se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1c175fa08a3e3b2ccff8db80b4c12b1
https://doi.org/10.1038/sj.bjp.0705229
https://doi.org/10.1038/sj.bjp.0705229
Autor:
Eiji Kurosaki, Akiyoshi Shimaya, Ryosuke Nakano, Masayuki Shibasaki, Hisataka Shikama, Kazuhiro Momose, Takayuki Suzuki
Publikováno v:
Japanese Journal of Pharmacology. 89:274-281
We studied the role of hepatic glycogenesis in glucose intolerance after glucose loading in obese Zucker rats and the effects of YM440 ((Z)-1,4-bis{4-[(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)methyl]phen-oxy}but-2-ene) on it. Lean and obese Zucker rats we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a152cd9767e6606c22c1678483c1987e
https://doi.org/10.1254/jjp.89.274
https://doi.org/10.1254/jjp.89.274
Autor:
Jianglin Fan, Hisataka Shikama, Tomonaga Ichikawa, Huijun Sun, Santica M. Marcovina, Hiroyuki Unoki, Teruo Watanabe, Hiroaki Shimoyamada
Publikováno v:
The American Journal of Pathology. 160:227-236
Elevated plasma lipoprotein(a) [Lp(a)] levels constitute an independent risk factor for the development of atherosclerosis. However, the mechanism underlying Lp(a) atherogenicity is unclear. Recently, we demonstrated that Lp(a) may potentially be pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ca06cbebc23de411044cc38f12a76a
https://doi.org/10.1016/s0002-9440(10)64366-0
https://doi.org/10.1016/s0002-9440(10)64366-0