Zobrazeno 1 - 10
of 790
pro vyhledávání: '"Hisataka, Moriwaki"'
Publikováno v:
International Journal of Translational Medicine, Vol 3, Iss 4, Pp 487-495 (2023)
Inhibitory effects of 4,5-didehydrogeranylgeranoic acid (dGGA) on the development of tumors were investigated in spontaneous hepatoma mice, C3H/HeNCrj. Experiment 1: Male mice at 8 weeks of age were raised on a basal diet, and then provided with a di
Externí odkaz:
https://doaj.org/article/de41d2488a0f47289eba03b8eececb32
Autor:
Hisataka Moriwaki, Takuji Tanaka, Hisashi Tsurumi, Koji Takai, Masaya Kubota, Yoichi Yasuda, Junpei Iwasa, Yohei Shirakami, Hiroyasu Sakai, Masahito Shimizu
Supplementary Table S1 from Acyclic Retinoid Inhibits Diethylnitrosamine-Induced Liver Tumorigenesis in Obese and Diabetic C57BLKS/J- +Leprdb/+Leprdb Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7db30b337550f6d29b3750a7a21c3e
https://doi.org/10.1158/1940-6207.22525442.v1
https://doi.org/10.1158/1940-6207.22525442.v1
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
The cells were seeded in 96 well plates 24 h before treatment with AA in the presence and absence of 10 μM ACR in DMEM containing 5% FBS. After 48 h, cell viability was determined using the Cell Counting Kit-8. Quantitative data normalized to EtOH c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237f594b7a25ac0aeec5617acafbff30
https://doi.org/10.1158/1940-6207.22534738
https://doi.org/10.1158/1940-6207.22534738
Autor:
Hisataka Moriwaki, Takuji Tanaka, Hisashi Tsurumi, Koji Takai, Masaya Kubota, Yoichi Yasuda, Junpei Iwasa, Yohei Shirakami, Hiroyasu Sakai, Masahito Shimizu
Obesity and the related metabolic abnormalities are associated with increased risk of hepatocellular carcinoma (HCC). Malfunctioning of retinoid X receptor (RXR) α due to phosphorylation by Ras/MAPK also plays a critical role in liver carcinogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a2df874b0b3ffdaa02d12baa5f759ac
https://doi.org/10.1158/1940-6207.c.6544748
https://doi.org/10.1158/1940-6207.c.6544748
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
Acyclic retinoid (ACR) is a promising drug under clinical trials for preventing recurrence of hepatocellular carcinoma. The objective of this study was to gain insights into molecular basis of the antitumorigenic action of ACR from a metabolic point
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a6e50cda6038be4923a0aa8e53820e5
https://doi.org/10.1158/1940-6207.c.6547624.v1
https://doi.org/10.1158/1940-6207.c.6547624.v1
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
The relative quantities of the detected metabolites involved in glycolysis/glyconeogenesis (A), the urea cycle (B), pyrimidine metabolism (C), amino acid metabolism (D), and nicotinate and nicotinamide metabolism (E) are represented as bar graphs (fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cb744813b01003684700fd0f1eb083
https://doi.org/10.1158/1940-6207.22534726
https://doi.org/10.1158/1940-6207.22534726
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
Relative intensity of 254 cationic metabolites detected using CE-TOFMS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97780b7933f87a9308c115947f02af9c
https://doi.org/10.1158/1940-6207.22534732.v1
https://doi.org/10.1158/1940-6207.22534732.v1
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
The cells were seeded in 10 cm dishes and allowed to grow to confluency. Cells were treated with 15 μM ACR in FBS free DMEM for 24 h. The cell lysates were isolated and the contents of AA was measured using an ELISA kit (CEB098Ge, Cloud-Clone Corp.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289dd7d6f5514c986cc271f73171ee9b
https://doi.org/10.1158/1940-6207.22534735
https://doi.org/10.1158/1940-6207.22534735
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
Relative intensity of 102 lipophilic metabolites detected using LC-TOFMS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17d83eaf62b69884a2d5438bd3db7773
https://doi.org/10.1158/1940-6207.22534729
https://doi.org/10.1158/1940-6207.22534729
Autor:
Soichi Kojima, Hisataka Moriwaki, Masahito Shimizu, Naoto Ishibashi, Yohei Shirakami, Kiyotaka Hitomi, Hideki Tatsukawa, Xian-Yang Qin
Boxplot of quantitative data displays the full range of variation (from min to max). n.s., not significant.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12adcfe90245b0f3f9aa548c28051d99
https://doi.org/10.1158/1940-6207.22534723
https://doi.org/10.1158/1940-6207.22534723