Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Hisashi Umemori"'
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100742- (2021)
Summary: The visual system is the best system to study activity-dependent sensory circuit development. The connections from the retina to the dorsal lateral geniculate nucleus, the retinogeniculate connections, undergo extensive remodeling during ear
Externí odkaz:
https://doaj.org/article/8a9a6a12c47c404ea6c783c7e9360ebb
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 9 (2017)
Various growth factors regulate synapse development and neurogenesis, and are essential for brain function. Changes in growth factor signaling are implicated in many neuropsychiatric disorders such as depression, autism and epilepsy. We have previous
Externí odkaz:
https://doaj.org/article/c69711472f7e461687831d0110837b2c
Autor:
Rebecca S Mathew, Antonis Tatarakis, Andrii Rudenko, Erin M Johnson-Venkatesh, Yawei J Yang, Elisabeth A Murphy, Travis P Todd, Scott T Schepers, Nertila Siuti, Anthony J Martorell, William A Falls, Sayamwong E Hammack, Christopher A Walsh, Li-Huei Tsai, Hisashi Umemori, Mark E Bouton, Danesh Moazed
Publikováno v:
eLife, Vol 5 (2016)
The SNARE-mediated vesicular transport pathway plays major roles in synaptic remodeling associated with formation of long-term memories, but the mechanisms that regulate this pathway during memory acquisition are not fully understood. Here we identif
Externí odkaz:
https://doaj.org/article/acd37fa8358f4746bfe77840b6ba1e10
Publikováno v:
eLife, Vol 5 (2016)
Communication between pre- and postsynaptic cells promotes the initial organization of synaptic specializations, but subsequent synaptic stabilization requires transcriptional regulation. Here we show that fibroblast growth factor 22 (FGF22), a targe
Externí odkaz:
https://doaj.org/article/a24378f8445340dabffc8f5009b2b060
Publikováno v:
The Neuroscientist. :107385842311701
The refinement of immature neuronal networks into efficient mature ones is critical to nervous system development and function. This process of synapse refinement is driven by the neuronal activity–dependent competition of converging synaptic input
Publikováno v:
Current Opinion in Neurobiology. 79:102692
Autor:
Naosuke Hoshina, Erin M. Johnson-Venkatesh, Veronica R. Rally, Jaanvi Sant, Miyuki Hoshina, Mariel P. Seiglie, Hisashi Umemori
Publikováno v:
J Neurosci
TheProtocadherin-10(PCDH10) gene is associated with autism spectrum disorder (ASD), obsessive-compulsive disorder (OCD), and major depression (MD). The PCDH10 protein is a homophilic cell adhesion molecule that belongs to the δ2-protocadherin family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15647b2d046c7d1199f8c18cac2831d2
https://europepmc.org/articles/PMC9145243/
https://europepmc.org/articles/PMC9145243/
Publikováno v:
NeuroReport. 31:125-130
Growth factor signaling in the brain is implicated in many neuropsychiatric disorders, including depression, autism, and epilepsy. Fibroblast growth factor 22 is a growth factor that regulates excitatory synapse development and neurogenesis in the br
Autor:
Ariane Pereira, Jeff A. Stogsdill, Gesine Saher, Peter Scheiffele, Lisa Traunmüller, Klaus-Armin Nave, Jiexin Wang, Chris J. McBain, Naosuke Hoshina, Huda Y. Zoghbi, Yu Itoh-Maruoka, Cagla Eroglu, Wei-Hsiang Huang, Fritz Benseler, Thomas Philips, Constance L. Cepko, Mateusz C. Ambrozkiewicz, Jeremy N. Kay, Hiroshi Kawabe, Vania F. Prado, Kevin T. Beier, Wenjia You, Nils Brose, Harold A. Burgess, Wei Lu, Junko Motohashi, Pascal S. Kaeser, Liqun Luo, Marco A. M. Prado, Elisabetta Furlanis, Emily Ling-Lin Pai, Kenji Sakimura, Kenji Mandai, John L.R. Rubenstein, Andrea M. Gomez, Emilie Dumontier, Michisuke Yuzaki, Hisashi Umemori, Yoshimi Takai, Jean-François Cloutier, Susanne Falkner, Laura A. Lavery, Sandra Goebbels, Matthijs Verhage, Ann Marie Craig, Cui Chen, Kenneth A. Pelkey, Wei Li, Nashat Abumaria, Joshua R. Sanes, Lin Luo, Jeffrey D. Rothstein, Joke Wortel, Jennifer L. Sinclair, Mary Anne Hutchison, Tomohiko Maruo
Publikováno v:
Neuron, vol 106, iss 1
Luo, L, Ambrozkiewicz, M C, Benseler, F, Chen, C, Dumontier, E, Falkner, S, Furlanis, E, Gomez, A M, Hoshina, N, Huang, W H, Hutchison, M A, Itoh-Maruoka, Y, Lavery, L A, Li, W, Maruo, T, Motohashi, J, Pai, E L L, Pelkey, K A, Pereira, A, Philips, T, Sinclair, J L, Stogsdill, J A, Traunmüller, L, Wang, J, Wortel, J, You, W, Abumaria, N, Beier, K T, Brose, N, Burgess, H A, Cepko, C L, Cloutier, J F, Eroglu, C, Goebbels, S, Kaeser, P S, Kay, J N, Lu, W, Luo, L, Mandai, K, McBain, C J, Nave, K A, Prado, M A M, Prado, V F, Rothstein, J, Rubenstein, J L R, Saher, G, Sakimura, K, Sanes, J R, Scheiffele, P, Takai, Y, Umemori, H, Verhage, M, Yuzaki, M, Zoghbi, H Y, Kawabe, H & Craig, A M 2020, ' Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines : Prevalence of Germline Recombination and Influencing Factors ', Neuron, vol. 106, no. 1, pp. 37-65.e5 . https://doi.org/10.1016/j.neuron.2020.01.008
Neuron, 106(1), 37-65.e5. Cell Press
Neuron
Luo, L, Ambrozkiewicz, M C, Benseler, F, Chen, C, Dumontier, E, Falkner, S, Furlanis, E, Gomez, A M, Hoshina, N, Huang, W H, Hutchison, M A, Itoh-Maruoka, Y, Lavery, L A, Li, W, Maruo, T, Motohashi, J, Pai, E L L, Pelkey, K A, Pereira, A, Philips, T, Sinclair, J L, Stogsdill, J A, Traunmüller, L, Wang, J, Wortel, J, You, W, Abumaria, N, Beier, K T, Brose, N, Burgess, H A, Cepko, C L, Cloutier, J F, Eroglu, C, Goebbels, S, Kaeser, P S, Kay, J N, Lu, W, Luo, L, Mandai, K, McBain, C J, Nave, K A, Prado, M A M, Prado, V F, Rothstein, J, Rubenstein, J L R, Saher, G, Sakimura, K, Sanes, J R, Scheiffele, P, Takai, Y, Umemori, H, Verhage, M, Yuzaki, M, Zoghbi, H Y, Kawabe, H & Craig, A M 2020, ' Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines : Prevalence of Germline Recombination and Influencing Factors ', Neuron, vol. 106, no. 1, pp. 37-65.e5 . https://doi.org/10.1016/j.neuron.2020.01.008
Neuron, 106(1), 37-65.e5. Cell Press
Neuron
The Cre-loxP system is invaluable for spatial and temporal control of gene knockout, knockin, and reporter expression in the mouse nervous system. However, we report varying probabilities of unexpected germline recombination in distinct Cre driver li
Publikováno v:
Science. 372
More is not always better Mutations in X-linked genes usually affect male individuals more than females, but the opposite characterizes the Protocadherin-19 gene ( PCDH19 ) on the X chromosome. Mutations in the PCDH19 cell-adhesion molecule cause cog