Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hisashi Tamaru"'
Publikováno v:
PLoS Genetics, Vol 7, Iss 12, p e1002423 (2011)
Eukaryotic genomes are partitioned into active and inactive domains called euchromatin and heterochromatin, respectively. In Neurospora crassa, heterochromatin formation requires methylation of histone H3 at lysine 9 (H3K9) by the SET domain protein
Externí odkaz:
https://doaj.org/article/94a0e2cfbff947b599e87336becaadde
Autor:
David Twell, Lucyna Slusarz, János Bindics, Nina Chumak, Claudia Köhler, Hisashi Tamaru, Vera K. Schoft
Publikováno v:
Plant Reproduction. 28:61-72
Key message: Purification of pollen nuclei. Germ cell epigenetics is a critical topic in plants and animals. The male gametophyte (pollen) of flowering plants is an attractive model to study genetic and epigenetic reprogramming during sexual reproduc
Autor:
Vera K. Schoft, Yeonhee Choi, Magdalena Mosiolek, Guen Tae Park, Marcelina García-Aguilar, Michael J. Hannon, Hisashi Tamaru, Robert L. Fischer, Adriana Machlicova, Jin Sup Park, Lucyna Slusarz, Nina Chumak
Publikováno v:
Proceedings of the National Academy of Sciences. 108:8042-8047
In double fertilization, the vegetative cell of the male gametophyte (pollen) germinates and forms a pollen tube that brings to the female gametophyte two sperm cells that fertilize the egg and central cell to form the embryo and endosperm, respectiv
Autor:
Vukoslav Komnenovic, Nina Chumak, Hisashi Tamaru, Lynette Brownfield, Vera K. Schoft, Tetsuji Kakutani, Magdalena Mosiolek, David Twell, Lucyna Slusarz
Publikováno v:
EMBO reports. 10:1015-1021
Centromeric constitutive heterochromatin is marked by DNA methylation and dimethylated histone H3 Lys 9 (H3K9me2) in Arabidopsis. RNA-directed DNA methylation (RdDM) is a process that uses 24-nucleotide (nt) small interfering RNAs (siRNAs) to induce
Autor:
Hisashi Tamaru, Makoto Tachibana, Yoichi Shinkai, Eric U. Selker, Da Jia, Xing Zhang, Kristina M. Smith, Xiaodong Cheng, Robert E. Collins
Publikováno v:
Journal of Biological Chemistry. 280:5563-5570
The functional significance of mono-, di-, and tri-methylation of lysine residues within histone proteins is under investigation. Evidence from several model organisms suggests that different methylated states of H3 Lys(9) (H3K9) are generated by spe
Autor:
Eric U. Selker, Hisashi Tamaru
Publikováno v:
Molecular and Cellular Biology. 23:2379-2394
Most 5-methylcytosine in Neurospora crassa occurs in A:T-rich sequences high in TpA dinucleotides, hallmarks of repeat-induced point mutation. To investigate how such sequences induce methylation, we developed a sensitive in vivo system. Tests of var
Autor:
Eric U. Selker, Gregory O. Kothe, C. David Allis, Michael R. Rountree, Hisashi Tamaru, Michael Freitag, Brian S. Margolin
Publikováno v:
Proceedings of the National Academy of Sciences. 99:16485-16490
One can imagine a variety of mechanisms that should result in self-perpetuating biological states. It is generally assumed that cytosine methylation is propagated in eukaryotes by enzymes that specifically methylate hemimethylated symmetrical sites (
Autor:
Vera K. Schoft, Daniel Zilberman, Robert L. Fischer, Adriana Machlicova, Denisse Rojas, Tzung-Fu Hsieh, Nina Chumak, Toshiro Nishimura, Hisashi Tamaru, Christian A. Ibarra, Jéssica Rodrigues, Rie Uzawa, Assaf Zemach, Xiaoqi Feng
Publikováno v:
Science (New York, N.Y.). 337(6100)
Intergenerational Transposable Shutdown Transposable elements (TEs) are a potential threat, especially to the germline genome. In many eukaryotes, TEs are shut down by DNA methylation and/or small-RNA–mediated silencing. Therefore, it seems counter
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 7, Iss 12, p e1002423 (2011)
PLoS Genetics, Vol 7, Iss 12, p e1002423 (2011)
Eukaryotic genomes are partitioned into active and inactive domains called euchromatin and heterochromatin, respectively. In Neurospora crassa, heterochromatin formation requires methylation of histone H3 at lysine 9 (H3K9) by the SET domain protein
Autor:
Hisashi Tamaru
Publikováno v:
Genesdevelopment. 24(14)
Heterochromatin is typically highly condensed, gene-poor, and transcriptionally silent, whereas euchromatin is less condensed, gene-rich, and more accessible to transcription. Besides acting as a graveyard for selfish mobile DNA repeats, heterochroma