Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hisashi Takasu"'
Autor:
Margherita T. Cantorna, Ann Prentice, Leif Moskilde, Hector F. DeLuca, Hisashi Takasu, Christel Lamberg-Allardt, Michael D. Sitrin, Bo Angelin, Mark R. Haussler, Haakon E. Meyer, Heide S. Cross, Robert P. Heaney, Moray J. Campbell, Olle Hernell, Cutberto Garza, David J. Mangelsdorf, Johan Emelian Moan, Steve A Abrams, Pentti Tuohimaa, Chantal Mathieu, Philip James, Irv Rosenberg, Michael F. Holick, Jan I. Pedersen
Publikováno v:
Nutrition Reviews. 66:S195-S212
The classic role of vitamin D has involved its function in calcium metabolism. However, a much broader perspective of the importance of vitamin D is now emerging. Therefore, a new approach is needed based on a combination of molecular biological, phy
c-Fos protein as a target of anti-osteoclastogenic action of vitamin D, and synthesis of new analogs
Autor:
Yasushi Uchiyama, Kyoji Ikeda, Nobuyoshi Katagiri, Hisashi Takasu, Makoto Okazaki, Atsuko Sugita, Etsuro Ogata
Publikováno v:
Journal of Clinical Investigation. 116:528-535
Although active vitamin D drugs have been used for the treatment of osteoporosis, how the vitamin D receptor (VDR) regulates bone cell function remains largely unknown. Using osteoprotegerin-deficient mice, which exhibit severe osteoporosis due to ex
Autor:
Hisashi Takasu
Publikováno v:
Nutrition Reviews. 66:S113-S115
Active vitamin D and its analogs, which have been recognized to potentiate both bone resorption and formation, increase bone volume by inhibiting accelerated bone resorption at pharmacological doses. This mechanism is, at least in part, independent o
Autor:
Minoru Morikawa, Seiichi Uesugi, Seitaro Shimokawa, Ken-ichi Tomita, Morio Ikehara, Takao Hayakawa, Satoshi Nishikawa, Akira Tanaka, Hisashi Takasu, Eriko Uchida
Publikováno v:
Biological and Pharmaceutical Bulletin. 18:797-801
Our previous work has shown that the amino acid residues around 62-67 located in the connecting loop between helix I and II of human growth hormone (hGH) are important in eliciting the differentiation of preadipose 3T3-F442A cells to adipocytes. In t
Autor:
Naoki Kubota, Isamu Nagai, Kenji Kumaki, Etsuro Ogata, Hisashi Takasu, Kiichiro Nakajima, Shumpei Sakakibara, Kazuo Chihara, Terutoshi Kimura, Yasushi Uchiyama, Hisamitsu Baba, Noriyuki Inomata
Publikováno v:
Journal of Bone and Mineral Metabolism. 12:S131-S134
We have recently demonstrated that the carboxyl-terminal (C-terminal) PTH fragments increase or decrease alkaline phosphatase activity in dexamethasone-treated ROS 17/2.8 cells, depending on the length of deletion of amino-terminal amino acids of the
Autor:
Isamu Nagai, Kenji Kumaki, Terutoshi Kimura, Naokt Kubota, Takuo Fujita, Noriyuki Inomata, Kiichiro Nakajima, Akira Matsumoto, Kazuo Chihara, Hisashi Takasu, Yasushi Uchiyama, Shumpei Sakakibara, Hisamitsu Baba
Publikováno v:
Endocrinology. 137(12)
We evaluated the competitive inhibitory effect of intact PTH, the amino-terminal PTH(1-34) fragment, and a series of truncated carboxyl-terminal PTH fragments on the binding of internally 35S-labeled human PTH(1-84) ([35S]hPTH(1-84)) to osteoblastic
Publikováno v:
Rapid communications in mass spectrometry : RCM. 9(4)
Peptide maps of recombinant human parathyroid hormone (rhPTH) were determined by both trypsin and V-8 protease digestion with subsequent fast-atom bombardment mass spectrometry (FAB-MS). Coverage of the sequence was 85% when using trypsin and 90% whe
Autor:
Morio Ikehara, Takao Hayakawa, Seiichi Uesugi, Satoshi Nishikawa, Minoru Morikawa, Akira Tanaka, Eriko Uchida, Yoshitaka Nishida, Ken-ichi Tomita, Seitaro Shimokawa, Hisashi Takasu
Publikováno v:
Biochemical and biophysical research communications. 172(1)
Summary In order to elucidate the active sites of growth hormone for eliciting the differentiation of preadipose 3T3-F442A cells to adipocytes, four artificial mutant variants of human growth hormone(hGH) modified in the loop region of amino acid res
Metal Chelate Compounds with Tetracycline Derivatives. VII. : The Structure of Tetracycline Chelates
Publikováno v:
Chemical and Pharmaceutical Bulletin. 6:1-9
Terramycin and Achromycin form chelate compounds with various metals, especially stable compounds with zirconium and thorium, as previously reported with Aureomycin. Their molar ratio is 1:1 in thorium chelates and 1:2 in zirconium chelates. Further
Autor:
Chikako Hayashi, Hisashi Takasu
Publikováno v:
Journal of Japan Cosmetic Chemists Association. 5:30-35
The effect of electrolytes on the viscosity of the emulsions of liquid paraffin stabilized by a series of alkyl ethoxy phosphates have been investigated.It is a well known fact that the viscosity of emulsions is changed by the addition of electrolyte