Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Hisashi Takano"'
Autor:
Sheo B. Singh, Christopher M. Tan, David Kaelin, Peter T. Meinke, Lynn Miesel, David B. Olsen, Hideyuki Fukuda, Ryuta Kishii, Masaya Takei, Kohei Ohata, Tomoko Takeuchi, Taku Shibue, Hisashi Takano, Akinori Nishimura, Yasumichi Fukuda
Publikováno v:
Bioorganicmedicinal chemistry letters. 75
Novel bacterial topoisomerase inhibitors (NBTIs) are the newest members of gyrase inhibitor broad-spectrum antibacterial agents, represented by the most advanced member, gepotidacin, a 4-amino-piperidine linked NBTI, which is undergoing phase III cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88fe127252145bd1368ad8cd0c89f1d
https://pubmed.ncbi.nlm.nih.gov/35609741
https://pubmed.ncbi.nlm.nih.gov/35609741
Autor:
Ho Hoang Huy, Julian Sasaki, Nguyen Huynh Duy Khang, Shota Namba, Pham Nam Hai, Quang Le, Brian York, Cherngye Hwang, Xiaoyong Liu, Michael Gribelyuk, Xiaoyu Xu, Son Le, Michael Ho, Hisashi Takano
Publikováno v:
Applied Physics Letters. 122:052401
It is technically challenging to shrink the size of a tunneling magnetoresistance reader to below 20 nm for magnetic recording technology beyond 4 Tb/in2 due to its complex film stack. Recently, we proposed a reader architecture based on the inverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4ab0897dd45b7f83a32ffd947a1734
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100885313
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100885313
Autor:
Jingjun Yin, Kouhei Oohata, Peter T. Meinke, Armando Lagrutta, David E. Kaelin, Lynn Miesel, Charles Gill, Hideyuki Fukuda, Charles G. Garlisi, Sheo B. Singh, Yasumichi Fukuda, Christopher M. Tan, Toussaint Nathalie Y, Taku Shibue, Tomoko Takeuchi, Hisashi Takano, Ryuta Kishii, Masaya Takei, David B. Olsen, Akinori Nishimura, Jin Wu, Takayuki Tsuchiya
Publikováno v:
Antimicrobial Agents and Chemotherapy. 60:4830-4839
Oxabicyclooctane-linked novel bacterial topoisomerase inhibitors (NBTIs) represent a new class of recently described antibacterial agents with broad-spectrum activity. NBTIs dually inhibit the clinically validated bacterial targets DNA gyrase and top
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d13383dbf940731b0d5857d379597c7
https://doi.org/10.1128/aac.00619-16
https://doi.org/10.1128/aac.00619-16
Autor:
Sheo B. Singh, David E. Kaelin, Jin Wu, Lynn Miesel, Christopher M. Tan, Peter T. Meinke, David B. Olsen, Armando Lagrutta, Changqing Wei, Xuanjia Peng, Xiu Wang, Hideyuki Fukuda, Ryuta Kishii, Masaya Takei, Takeshi Shibata, Kohei Ohata, Hisashi Takano, Haruaki Kurasaki, Tomoko Takeuchi, Akinori Nishimura, Yasumichi Fukuda
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:2409-2415
Bacterial resistance is rapidly growing, necessitating the need to discover new agents. Novel bacterial topoisomerase inhibitors (NBTIs) are new class of broad-spectrum antibacterial agents targeting bacterial DNA gyrase and topoisomerase IV. This cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974aa81be7744ca2bcc4cdedab8abe8e
https://doi.org/10.1016/j.bmcl.2015.04.002
https://doi.org/10.1016/j.bmcl.2015.04.002
Autor:
Leo A. Joyce, David E. Kaelin, Peter T. Meinke, Takeshi Shibata, Keith W. Rickert, Masaya Takei, Sangita B. Patel, Changqing Wei, Xiu Wang, Xuanjia Peng, David B. Olsen, Armando Lagrutta, Jun Lu, Masanobu Yajima, Yasumichi Fukuda, Jin Wu, Mitsuhito Shibasaki, Hideyuki Fukuda, Lynn Miesel, Christopher M. Tan, Stephen M. Soisson, Todd A. Black, Ryuta Kishii, Robert F. Smith, Ravi P. Nargund, Edward C. Sherer, Hisashi Takano, Sheo B. Singh, Akinori Nishimura
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1831-1835
Novel bacterial topoisomerase inhibitors (NBTIs) represent a new class of broad-spectrum antibacterial agents targeting bacterial Gyrase A and ParC and have potential utility in combating antibiotic resistance. A series of novel oxabicyclooctane-link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004e6e7ff7e7a7d762ad92dba34bd9d3
https://doi.org/10.1016/j.bmcl.2015.03.044
https://doi.org/10.1016/j.bmcl.2015.03.044
Autor:
Hisashi Takano
Publikováno v:
Journal of The Japan Institute of Electronics Packaging. 15:439-442
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f15e2a848fc382b54b1663c364a68b04
https://doi.org/10.5104/jiep.15.439
https://doi.org/10.5104/jiep.15.439
Autor:
Takashi Komine, Yasumichi Fukuda, Tatsuhiro Saito, Yoshikazu Asahina, Akihiko Kojima, Taku Shibue, Hisashi Takano
Publikováno v:
Journal of Medicinal Chemistry. 51:6558-6562
Novel antibacterial biaryl oxazolidinones bearing an aza-, an oxa-, or a thiabicyclo[3.1.0]hex-6-yl ring system were synthesized, and their in vitro antibacterial activity and structure-activity relationships (SAR) were evaluated. Most of the synthes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09305bc38788cee7075d919cdefdebaf
https://doi.org/10.1021/jm800800c
https://doi.org/10.1021/jm800800c
Autor:
Ryuta Kishii, David E. Kaelin, Armando Lagrutta, David B. Olsen, Peter T. Meinke, Kohei Ohata, Jin Wu, Sheo B. Singh, Hideyuki Fukuda, Lynn Miesel, Tomoko Takeuchi, Hisashi Takano, Akinori Nishimura, Yasumichi Fukuda, Masaya Takei, Takeshi Shibata, Haruaki Kurasaki, Christopher M. Tan
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(17)
Oxabicyclooctane linked novel bacterial topoisomerase inhibitors (NBTIs) are new class of recently reported broad-spectrum antibacterial agents. They target bacterial DNA gyrase and topoisomerase IV and bind to a site different than quinolones. They
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50eef89ff9ae0c2472947cdaa6e487b
https://pubmed.ncbi.nlm.nih.gov/26152426
https://pubmed.ncbi.nlm.nih.gov/26152426
Autor:
Peter T. Meinke, Kohei Ohata, Xiu Wang, Ravi P. Nargund, David E. Kaelin, Tomoko Takeuchi, Hisashi Takano, Christopher M. Tan, Hideyuki Fukuda, Lynn Miesel, Xuanjia Peng, Yasumichi Fukuda, Akinori Nishimura, Masaya Takei, Changqing Wei, Sheo B. Singh, Shizuka Ban, Taku Shibue, Armando Lagrutta, Todd A. Black, Charles Gill, David B. Olsen, Jin Wu, Ryuta Kishii
Publikováno v:
Bioorganicmedicinal chemistry letters. 25(12)
Novel bacterial topoisomerase inhibitors (NBTIs) are a new class of broad-spectrum antibacterial agents targeting bacterial Gyrase A and ParC and have potential utility in combating antibiotic resistance. (R)-Hydroxy-1,5-naphthyridinone left-hand sid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fccf7e247dbee77a91c503236ee840
https://pubmed.ncbi.nlm.nih.gov/25978963
https://pubmed.ncbi.nlm.nih.gov/25978963
Autor:
Yasunori Tsuchiya, Yuta Shimura, Toshiaki Suzuki, Yoshitaka Hamashima, Mikiko Sodeoka, Tomomi Goto, Hisashi Takano, Ken-ichi Moriya
Publikováno v:
Tetrahedron. 62:7168-7179
Using chiral palladium enolates as key intermediates, efficient catalytic enantioselective fluorination reactions of active methine compounds have been developed. These reactions can be conducted in alcoholic solvents without any precaution to exclud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f95657aabc3e93264d8dcf3b98ee69b
https://doi.org/10.1016/j.tet.2005.12.070
https://doi.org/10.1016/j.tet.2005.12.070