Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hisashi Shirohara"'
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 274:G406-G412
Plasma cholecystokinin (CCK) levels in fed rats increased from 2.59 ± 0.13 pmol/l to the peak of 27.6 ± 4.1 pmol/l at 1 h after a single oral administration of synthetic protease inhibitor (PI; ethyl N-allyl- N-{( E)-2-methyl-3-[4-(4-amidino-phenox
Autor:
Hisashi Shirohara, Makoto Otsuki
Publikováno v:
Pancreas. 14:249-254
Recent studies have shown that cholecystokinin (CCK) is involved in the induction and development of acute pancreatitis in experimental animals. In the present study we determined basal plasma CCK concentrations by a specific and sensitive radioimmun
Publikováno v:
Diabetes Research and Clinical Practice. 31:27-35
There is strong evidence that genetic factors contribute to the development of obesity in humans as well as laboratory animals. Another important factor leading to obesity is an increase in energy intake. However, it is difficult to make normal rats
Autor:
Hayato Nakamura, Kenji Kanagawa, Makoto Otsuki, Hisashi Shirohara, Mitsuyoshi Yamamoto, Ken-Ichiro Fukumitsu, Mitsuo Tashiro, Yoshihide Hirohata, Hiroyuki Yoshikawa, Yasuyuki Kihara
Publikováno v:
Journal of gastroenterology. 33(5)
Recent studies in genetically obese and diabetic Otsuka Long-Evans Tokushima Fatty (OLETF) rats suggest defects of cholecystokinin (CCK)-A receptor gene expression and CCK-A receptor-mediated biological functions such as pancreatic juice, protein, an
Publikováno v:
Scandinavian journal of gastroenterology. 33(8)
The aim of this study was to determine whether therapeutically used branched-chain amino acids (BCAAs) solution influences glucose metabolism in liver cirrhosis (LC).BCAAs solution (200 ml) was infused in LC patients at different stages, and plasma c
Autor:
Issei Tachibana, Shigekazu Nakano, Makoto Otsuki, Toshiharu Akiyama, Yoshihide Hirohata, Hisashi Shirohara, Nobuaki Watanabe, László Czakó
Publikováno v:
Pancreas. 14(2)
Recent studies provide significant evidence that cholecystokinin (CCK) is involved in the induction and development of acute pancreatitis in experimental animals. However, the results obtained with specific CCK-A (peripheral) receptor antagonists are
Autor:
Toshiharu Akiyama, Makoto Otsuki, Issei Tachibana, Hisashi Shirohara, Nobuaki Watanabe, Shigekazu Nakano
Publikováno v:
Pancreas. 12(2)
Summary The effects of a newly developed compound having antiulcer action, (Z)-2-(4-methylpiperazin-1-yl)-1-[4-(2-phenyl-ethyl)phenyl]-ethanone oxime hydrochloride monohydrate (MCI-727), on pancreatic exocrine secretion were studied in anesthetized r
Autor:
Toshiharu Akiyama, Issei Tachibana, Makoto Otsuki, Hisashi Shirohara, Nobuaki Watanabe, Shigekazu Nanano
Publikováno v:
International journal of pancreatology : official journal of the International Association of Pancreatology. 17(2)
The effects of tetraprenylacetone (TPN), an acyclic polyisoprenoid with antiulcer actions, on pancreatic exocrine secretion, and its preventive and therapeutic effects on acute pancreatitis in two experimental models were studied in rats. Intraduoden
Publikováno v:
Gastroenterology. 118:A68-A69
Autor:
Makoto Otsuki, Toshiharu Akiyama, Yoshihide Hirohata, Dongmei Jia, Hisashi Shirohara, Ken-Ichiro Fukumitsu
Publikováno v:
Gastroenterology. 118:A161