Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hisashi Nogawa"'
Publikováno v:
European Journal of Pharmacology. 927:175065
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b6af6fd3c72e625146f9ca0c8b4e4f5
https://doi.org/10.1016/j.ejphar.2022.175065
https://doi.org/10.1016/j.ejphar.2022.175065
Autor:
Hiroko Endo, Junko Shinozaki, Kaori Miyamoto, Chiho Nagasawa, Hitoshi Watanabe, Shinobu Suzuki, Shota Saiki, Chiaki Nakamori, Kiyotaka Koyabu, Yayoi Honda, Chiaki Nakayama, Ikumi Washio, Takeshi Kunimatsu, Hisashi Nogawa, Hiroshi Iwasaki, Etsushi Takahashi, Yumiko Nozaki, Atsuhiro Yamanishi, Tetsuji Itoh
Publikováno v:
Regulatory Toxicology and Pharmacology. 77:75-86
In vitro screening of hERG channels are recommended under ICH S7B guidelines to predict drug-induced QT prolongation and Torsade de Pointes (TdP), whereas proarrhythmia is known to be evoked by blockage of other ion channels involved in cardiac contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c3022873eb82f6c37aaf1b87424a3a
https://doi.org/10.1016/j.yrtph.2016.02.007
https://doi.org/10.1016/j.yrtph.2016.02.007
Autor:
Hidenori Hiranuma, Junko Shinozaki, Toru Hattori, Katsuyuki Kazusa, Atsuhiro Yamanishi, Xiaoyu Zhang, Hisashi Nogawa
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 105:106726
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e9aa7b3a569d16940ce3389d3ebc785
https://doi.org/10.1016/j.vascn.2020.106726
https://doi.org/10.1016/j.vascn.2020.106726
Publikováno v:
European Journal of Pharmacology. 720:29-37
The cholesterol-lowering drug, probucol, is known to induce QT interval prolongation and torsades de pointes in patients. Recent in vitro studies have indicated that probucol reduces hERG expression in the plasma membrane and does not directly block
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f881e59bc9a0c02bd279928881d41329
https://doi.org/10.1016/j.ejphar.2013.10.056
https://doi.org/10.1016/j.ejphar.2013.10.056
Autor:
Toshio Hashimoto, Yoshiyuki Motokawa, Katsuyoshi Chiba, Toshiki Kagawa, Kenta Watanabe, Kengo Sakamoto, Hisashi Nogawa, Jun Handa, Yukio Takahashi, Fuminori Matsubara, Akihiro Kanno, Harushige Ozaki, Ryouta Hayashi, Yuko Semi, Hiromi Negishi
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 88:184-185
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::add335dec73a2bbf6d572b2a2646e89d
https://doi.org/10.1016/j.vascn.2017.09.054
https://doi.org/10.1016/j.vascn.2017.09.054
Autor:
Shigeki Matsuzawa, Hisashi Nogawa, Kayoko Masuda, Takeshi Tsubuki, Tomoko Kameda, Yuji Ishibashi, Akitsu Ogawa
Publikováno v:
Respirology. 14:53-59
Background and objective Reactive oxygen species (ROS) play an important role in the pathogenesis of various respiratory diseases. Carbocisteine, a mucoregulatory drug, is used in the treatment of several disease states but little information is avai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe14a71dd949e535a29610641fa667d1
https://doi.org/10.1111/j.1440-1843.2008.01424.x
https://doi.org/10.1111/j.1440-1843.2008.01424.x
Publikováno v:
Journal of Bacteriology. 186:3806-3813
The cytotoxicity of Bordetella bronchiseptica to infected cells is known to be dependent on a B . bronchiseptica type III secretion system. Although BopB, BopN, BopD, and Bsp22 have been identified as type III secreted proteins, these proteins remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39bb063344be63a72449824f25fa30d
https://doi.org/10.1128/jb.186.12.3806-3813.2004
https://doi.org/10.1128/jb.186.12.3806-3813.2004
Publikováno v:
The Journal of Immunology. 170:413-420
The expression of MD-2, which associates with Toll-like receptor (TLR) 4 on the cell surface, confers LPS and LPS-mimetic Taxol responsiveness on TLR4. Alanine-scanning mutagenesis was performed to identify the mouse MD-2 residues important for confe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba588e94bf4979ef134506224bc700e
https://doi.org/10.4049/jimmunol.170.1.413
https://doi.org/10.4049/jimmunol.170.1.413
Autor:
Hisashi Nogawa, Tomoyuki Kawai
Publikováno v:
European journal of pharmacology. 741
Acquired long QT syndrome induced by non-cardiovascular drugs can cause lethal cardiac arrhythmia called torsades de points and is a significant problem in drug development. The prolongation of QT interval and cardiac action potential duration are ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16f2f1b1e76f6b65643ac025005d54c
https://pubmed.ncbi.nlm.nih.gov/24998878
https://pubmed.ncbi.nlm.nih.gov/24998878
Autor:
Kaori Miyamoto, Ikumi Washio, Hitoshi Watanabe, Chiaki Nakamori, Kohji Tanaka, Hiroshi Iwasaki, Atsuhiro Yamanishi, Kaoru Morimura, Yumiko Nozaki, Chiho Nagasawa, Shota Saiki, Chiaki Nakayama, Hisashi Nogawa, Takeshi Kunimatsu, Yayoi Honda, Etsushi Takahashi, Hiroko Endo, Shinobu Suzuki
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 81:385
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67feffcd533d3826f46305712bdeb92d
https://doi.org/10.1016/j.vascn.2016.02.163
https://doi.org/10.1016/j.vascn.2016.02.163