Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Hisashi Nagase"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2532 (2024)
Cancer immunotherapy is a type of cancer therapy utilizing the immune system to fight against tumors [...]
Externí odkaz:
https://doaj.org/article/eb688d5c3931412fb59beccc9a5dfb1a
Autor:
Hisashi Nagase, Kohzo Nakayama
Publikováno v:
Immunoregulatory Aspects of Immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d22347a733200d22975ce3d47b1d584
https://doi.org/10.5772/intechopen.75449
https://doi.org/10.5772/intechopen.75449
Autor:
Hisashi Nagase, Kohzo Nakayama
Publikováno v:
Current Drug Discovery Technologies. 11:243-258
Amyloid-β (Aβ) is widely believed to cause Alzheimer's disease (AD), as it is the major constituent of the amyloid plaques observed in the brains of people with AD (the so-called amyloid hypothesis). Based on this hypothesis, therapies utilizing im
Autor:
Kohzo Nakayama, Hisashi Nagase
Publikováno v:
Current Stem Cell Research & Therapy. 8:341-356
Notch signaling mediates the fates of numerous cells not only in the nervous system but also in the immune system. Notch signaling contributes to the generation and maintenance of hematopoietic stem cells, lymphocyte development, and several immune r
Publikováno v:
Current Psychopharmacologye. 1:155-166
Publikováno v:
Current Stem Cell Research & Therapy. 6:131-141
Notch signaling mediates the fates of numerous cells in both invertebrates and vertebrates. In the immune system, Notch signalling contributes to the generation of hematopoietic stem cells (HSCs), the promotion of HSC self-renewal, T lineage commitme
Publikováno v:
Cellular and Molecular Neurobiology. 31:887-900
Although γ-secretase was first identified as a protease that cleaves amyloid precursor protein (APP) within the transmembrane domain, thus producing Aβ peptides that are thought to be pathogenic in Alzheimer's disease (AD), its physiological functi
Publikováno v:
Gene. 475:1-9
Although amyloid precursor protein (APP) plays a central role in Alzheimer's disease, the physiological functions of this protein have yet to be fully elucidated. As previously reported, we established an embryonic carcinoma P19 cell line expressing
Publikováno v:
Current Stem Cell Research & Therapy. 3:288-302
In the canonical Notch signaling pathway, intramembrane cleavage by gamma-secretase serves to release an intracellular domain of Notch that has activity in the nucleus through binding to transcription factors. In addition, we showed that Notch also s
Publikováno v:
Neuroscience Letters. 444:127-131
Although amyloid precursor protein (APP) has central roles in Alzheimer's disease, the physiological functions of this protein have yet to be fully elucidated. APP homologues show significant sequence conservation in the intracellular domain through