Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Hisashi Murayama"'
Autor:
Makoto Kajiwara, Aya Takakura, Ryoko Takao-Kawabata, Sadakazu Ejiri, Hisashi Murayama, Yukihiro Isogai, Toshinori Ishizuya
Publikováno v:
Journal of Bone and Mineral Metabolism. 34:291-302
Bone histomorphometry is usually performed on the iliac bone in humans and the tibia or vertebrae in rats. Bone metabolism differences among skeletal sites may be problematic when translating experimental results from rats to humans, but data on such
Autor:
Hisashi Murayama, Ryoji Yao, Tatsuhiko Tanizawa, Noriyuki Yamamoto, Toyoshi Fukuda, Hideyuki Yamato, Tokio Higashi, Ibuki Yajima, Sakuyoshi Tabata
Publikováno v:
Therapeutic Apheresis and Dialysis. 13:83-87
A patient with secondary hyperparathyroidism (2 degrees HPT) underwent a total parathyroidectomy (PTx) without autotransplantation and showed interesting changes in the morphology of his iliac bone before and after the surgery. A 70-year-old man had
Autor:
Koji Ioku, Hideyuki Minagi, Yasuaki Shibata, Yoshinori Gonda, Tohru Ikeda, Masanobu Kamitakahara, Ikuho Yonezawa, Takatoshi Okuda, Hisashi Kurosawa, Hisashi Murayama, Giichiro Kawachi
Publikováno v:
Biomaterials. 29:2719-2728
A newly developed calcium-deficient hydroxyapatite composed of rod-shaped particles synthesized by the hydrothermal method (HHA) and stoichiometric hydroxyapatite (SHA) synthesized by the sintering method was used for in vivo implantation and in vitr
Autor:
Yasuaki Shibata, Hisashi Murayama, Shimeru Kamihira, Giichiro Kawachi, Koji Ioku, Hideyuki Minagi, Ikuho Yonezawa, Yoshinori Gonda, Takatoshi Okuda, Hisashi Kurosawa, Soichiro Minami, Tohru Ikeda
Publikováno v:
Biomaterials. 28:2612-2621
The response of bone cells to a newly developed porous beta-tricalcium phosphate composed of rod-shaped particles (RSbeta-TCP), beta-TCP composed of conventional non-rod-shaped particles (Cbeta-TCP), and hydroxyapatite (HA) was analyzed using in vivo
Autor:
Hideyuki Yamato, Ikuko Ezawa, Yoshiko Iwasaki-Ishizuka, Masafumi Fukagawa, Kiyoshi Kurokawa, Hisashi Murayama
Publikováno v:
Life Sciences. 76:1721-1734
Menatetrenone (MK-4) is a vitamin K2 homologue that has been used as a therapeutic agent for osteoporosis in Japan. However, there is no far any reported evidence that MK-4 ameliorates a pre-existing condition of reduced bone mineral density (BMD) in
Publikováno v:
Journal of Cellular Biochemistry. 90:267-277
It is known that pharmacological or toxic doses of vitamin D induce bone resorption both in vivo and in vitro, whereas physiological doses of the vitamin have a protective effect on bone in vivo. To investigate the discrepancies of the dose-dependent
Autor:
Takeshi Takahashi, Hideyuki Yamato, Masafumi Fukagawa, Kiyoshi Kurokawa, Ikuko Ezawa, Yoshiko Iwasaki, Masami Sato, Hisashi Murayama
Publikováno v:
Journal of Bone and Mineral Metabolism. 21:154-160
Bisphosphonate is a potent inhibitor of bone resorption, which results in the increase of bone volume. However, bisphosphonate treatment may lead to extremely low bone turnover and abnormal bone microstructure. In this study, we examined whether the
Autor:
Hideyuki Yamato, Ikuko Ezawa, Yoshiko Iwasaki-Ishizuka, Kei Takahashi, Masafumi Fukagawa, Hisashi Murayama, Kiyoshi Kurokawa, Masako Abe
Publikováno v:
Journal of Nutritional Science and Vitaminology. 49:256-261
Vitamin K2 (menaquinone) acts on the bone metabolism. Menatetrenon (MK-4) is a vitamin K2 homologue that has been used as a therapeutic agent for osteoporosis in Japan. Rat models of immobilization induced by sciatic neurectomy are characterized by t
Autor:
Kiyoshi Kurokawa, Hisashi Murayama, Hideyuki Yamato, Masafumi Fukagawa, Takeshi Takahashi, Yoshiko Iwasaki, Ikuko Ezawa
Publikováno v:
Japanese Journal of Pharmacology. 90:88-93
Menatetrenone (MK-4) inhibits bone resorption and enhances osteoblast-induced mineralization. In this study, we examined whether MK-4 administration had beneficial effects on osteoblast dysfunction and trabecular microstructure as well as on bone vol
Autor:
Tadashi Hayami, Kazumi Obara, Hisashi Murayama, Seiji Fukumoto, Kunihiko Tokunaga, Motoyuki Uchida, Naoto Endo, Ayako Fujieda, Hiroshi Yamagiwa, Hiroyuki Suzuki, Yumiko Nagai, Hideyuki Yamato
Publikováno v:
Journal of Bone and Mineral Metabolism. 19:207-212
Parathyroid hormone (PTH) increases serum calcium (Ca) by enhancing bone resorption and renal Ca reabsorption. However, detailed mechanisms of enhanced bone resorption by PTH remain to be elucidated. Although PTH has been shown to increase the expres