Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Hisashi Kanemaru"'
Autor:
Tsuyoshi Kadomatsu, Chiaki Hara, Ryoma Kurahashi, Haruki Horiguchi, Jun Morinaga, Keishi Miyata, Sohtaro Kurano, Hisashi Kanemaru, Satoshi Fukushima, Kimi Araki, Masaya Baba, W. Marston Linehan, Tomomi Kamba, Yuichi Oike
Publikováno v:
Molecular Oncology, Vol 17, Iss 12, Pp 2637-2658 (2023)
Loss or downregulation of major histocompatibility complex class I (MHC‐I) contributes to tumor immune evasion. We previously demonstrated that angiopoietin‐like protein 2 (ANGPTL2) promotes tumor progression using a Xp11.2 translocation renal ce
Externí odkaz:
https://doaj.org/article/77efc53feca24f4d9bfc397aad582af1
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101128- (2022)
Summary: Current standard assays to analyze lymphocyte-mediated antitumor cytotoxicity employ radioisotopic or fluorescent labels. However, such assays are not suitable for real-time analysis. Here we describe a protocol that facilitates the analysis
Externí odkaz:
https://doaj.org/article/2eab9fbe0c8e45758cb7720777494ba7
Autor:
Hisashi Kanemaru, Yukari Mizukami, Akira Kaneko, Hidemi Tagawa, Toshihiro Kimura, Haruka Kuriyama, Soichiro Sawamura, Ikko Kajihara, Katsunari Makino, Azusa Miyashita, Jun Aoi, Takamitsu Makino, Shinichi Masuguchi, Satoshi Fukushima, Hironobu Ihn
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103067- (2021)
Summary: Turning non-inflamed (cold) tumors into inflamed (hot) tumors is important for maximizing the effect of immune checkpoint inhibitors (ICIs) against malignancies. We showed that lactate, a product of the Warburg effect, inhibited the efficacy
Externí odkaz:
https://doaj.org/article/eeb1bbf24e304f84bde2b2f4e61404ba
Autor:
Kenta Maruyama, Yasunori Takayama, Erika Sugisawa, Yu Yamanoi, Takashi Yokawa, Takeshi Kondo, Ken-ichi Ishibashi, Bikash Ranjan Sahoo, Naoki Takemura, Yuki Mori, Hisashi Kanemaru, Yutaro Kumagai, Mikaël M. Martino, Yoshichika Yoshioka, Hisao Nishijo, Hiroki Tanaka, Atsushi Sasaki, Naohito Ohno, Yoichiro Iwakura, Yoshinori Moriyama, Masatoshi Nomura, Shizuo Akira, Makoto Tominaga
Publikováno v:
iScience, Vol 6, Iss , Pp 306-318 (2018)
Summary: Candida albicans infection can cause skin, vulvar, or oral pain. Despite the obvious algesic activity of C. albicans, the molecular mechanisms of fungal nociception remain largely unknown. Here we show that the C. albicans-specific signaling
Externí odkaz:
https://doaj.org/article/af790e5323b74bdb88c067532d689b01
Autor:
Kenta Maruyama, Yasunori Takayama, Takeshi Kondo, Ken-ichi Ishibashi, Bikash Ranjan Sahoo, Hisashi Kanemaru, Yutaro Kumagai, Mikaël M. Martino, Hiroki Tanaka, Naohito Ohno, Yoichiro Iwakura, Naoki Takemura, Makoto Tominaga, Shizuo Akira
Publikováno v:
Cell Reports, Vol 19, Iss 13, Pp 2730-2742 (2017)
Candida albicans can enter skeletal tissue through a skin wound in an immunocompromised host or by contamination during orthopedic surgery. Such Candida osteomyelitis is accompanied by severe pain and bone destruction. It is established that nocicept
Externí odkaz:
https://doaj.org/article/1d2bc973c974426cb9cc52333f235fa0
Autor:
Azusa Miyashita, Satoshi Fukushima, Satoshi Nakahara, Junji Yamashita, Aki Tokuzumi, Jun Aoi, Asako Ichihara, Hisashi Kanemaru, Masatoshi Jinnin, Hironobu Ihn
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144241 (2015)
Recent studies have shown that immunotherapies and molecular targeted therapies are effective for advanced melanoma. Non-antigen-specific immunotherapies such as immunocheckpoint blockades have been shown to be effective in the treatment of advanced
Externí odkaz:
https://doaj.org/article/68f18cff6df44cbfb3777e62ee8ea776
Autor:
Kenichiro TANAKA, Ikko KAJIHARA, Kazuro SHIMOKAWA, Naotoshi NAKAMURA, Yudo KUSABA, Ryoko SAKAMOTO, Saki MAEDA-OTSUKA, Saori YAMADA-KANAZAWA, Soichiro SAWAMURA, Hisashi KANEMARU, Katsunari MAKINO, Jun AOI, Shinichi MASUGUCHI, Takashi SUZUKI, Satoshi FUKUSHIMA
Publikováno v:
European Journal of Dermatology; mar/apr2024, Vol. 34 Issue 2, p182-192, 93p
Autor:
Yuki ICHIGOZAKI, Kayo KASHIWADA, Hisashi KANEMARU, Takamitsu MAKINO, Ikko KAJIHARA, Satoshi FUKUSHIMA
Publikováno v:
The Nishinihon Journal of Dermatology. 85:21-24
Autor:
Satoshi Fukushima, Azusa Miyashita, Haruka Kuriyama, Toshihiro Kimura, Satoru Mizuhashi, Yosuke Kubo, Satoshi Nakahara, Hisashi Kanemaru, Nobuhiro Tsuchiya, Hiroaki Mashima, Rong Zhang, Yasushi Uemura
Publikováno v:
Experimental Dermatology. 32:290-296
Cancer immunotherapy is now the first-line treatment for many unresectable cancers. However, it remains far from a complete cure for all patients. Therefore, it is necessary to develop innovative methods for cancer immunotherapy, and immune cell ther