Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Hisashi Haga"'
Autor:
Ryota Kobayashi, Emi Hoshikawa, Taisuke Saito, Orakarn Suebsamarn, Eriko Naito, Ayako Suzuki, Seiichiro Ishihara, Hisashi Haga, Kei Tomihara, Kenji Izumi
Publikováno v:
FEBS Open Bio, Vol 13, Iss 8, Pp 1469-1484 (2023)
We previously reported that the cell and colony motion of oral keratinocytes are correlated with proliferative capacity, and speculated that this may be a specific index for monitoring cell quality. However, how cell motility and proliferation are re
Externí odkaz:
https://doaj.org/article/a9ae0f981e3d423386d0c6ed649b4147
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Cell-containing collagen gels are one of the materials employed in tissue engineering and drug testing. A collagen gel is a useful three-dimensional (3D) scaffold that improves various cell functions compared to traditional two-dimensional p
Externí odkaz:
https://doaj.org/article/bf9faa3fb7e04d61a82bb8ec691f16da
Autor:
Ratih Kusumastuti, Yuji Kumagai, Seiichiro Ishihara, Atsushi Enomoto, Takashi Murakami, Motoaki Yasuda, Hisashi Haga
Publikováno v:
FEBS Open Bio, Vol 12, Iss 10, Pp 1797-1813 (2022)
Overexpression of human epidermal growth factor receptor 2 (HER2) in various cancers is correlated with poor patient survival. Trastuzumab, a recombinant humanized monoclonal antibody against HER2, has been considered to be a first‐line therapy for
Externí odkaz:
https://doaj.org/article/978b5ef6126c47b391c25c15c705d0d0
Autor:
Yuji Kumagai, Junko Nio-Kobayashi, Seiichiro Ishihara, Atsushi Enomoto, Masashi Akiyama, Ryosuke Ichihara, Hisashi Haga
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-12 (2022)
Abstract The process by which cancer cells invade as a cell cluster, known as collective invasion, is associated with metastasis and worse prognosis of cancer patients; therefore, inhibition of collective invasion is considered to improve cancer trea
Externí odkaz:
https://doaj.org/article/5a3bf3f44d854df0aedbe3b5626f2c03
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Astrocytes, which can be obtained from neural stem cells (NSCs) by adding serum and/or recombinant proteins in culture media or by passaging NSCs repeatedly, are expected to be applicable in regenerative medicine for the treatment of neurode
Externí odkaz:
https://doaj.org/article/72cf3d9f294e4037ae9862e6016158d2
Publikováno v:
Gels, Vol 9, Iss 2, p 148 (2023)
The stiffness of extracellular matrices (ECMs) is critical for cellular functions. Therefore, modulating the stiffness of ECMs in vitro is necessary to investigate the role of stiffness in cellular phenomena. Collagen gels are widely used for cell cu
Externí odkaz:
https://doaj.org/article/7f9fba682c2843eb9adea225304906f4
Autor:
Seiichiro Ishihara, Hisashi Haga
Publikováno v:
Cancers, Vol 14, Iss 4, p 1049 (2022)
Matrix stiffness is critical for the progression of various types of cancers. In solid cancers such as mammary and pancreatic cancers, tumors often contain abnormally stiff tissues, mainly caused by stiff extracellular matrices due to accumulation, c
Externí odkaz:
https://doaj.org/article/4f669b6ac4fe48268be4399d34929762
Publikováno v:
Data in Brief, Vol 6, Iss , Pp 793-798 (2016)
This data article describes cellular dynamics, such as migration speed and mobility of the cytoskeletal protein, of wild-type human fibroblast cells and cells with a modified adeno-associated virus integration site 1 (AAVS1) locus on human chromosome
Externí odkaz:
https://doaj.org/article/71ad5426b5b3494caf62d6d257a8b430
Publikováno v:
Regenerative Therapy, Vol 3, Iss C, Pp 90-96 (2016)
Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CMs) are expected to play an important role in heart therapies, in which hiPSC-CMs should generate sufficient contractile force to pump blood. However, recent studies have shown
Externí odkaz:
https://doaj.org/article/92c082f1d48a4b93a1d23c41188a39bc
Autor:
Takuya Kato, Atsushi Enomoto, Takashi Watanabe, Hisashi Haga, Sumire Ishida, Yuji Kondo, Koichi Furukawa, Takeshi Urano, Shinji Mii, Liang Weng, Maki Ishida-Takagishi, Masato Asai, Naoya Asai, Kozo Kaibuchi, Yoshiki Murakumo, Masahide Takahashi
Publikováno v:
Cell Reports, Vol 7, Iss 4, Pp 1156-1167 (2014)
For collective invasion, cancer cells form cohesive groups comprised of leading cells (LCs) at the forefront and following cells (FCs) at the rear. However, the molecular mechanisms that define LCs and FCs remain elusive. Here, we demonstrated that L
Externí odkaz:
https://doaj.org/article/493e936aeb0c4adf82153c7944217034