Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Hisashi, Hashimoto"'
Autor:
Takumi Wagatsuma, Eisuke Suzuki, Miku Shiotsu, Akiko Sogo, Yukina Nishito, Hideya Ando, Hisashi Hashimoto, Michael J. Petris, Masato Kinoshita, Taiho Kambe
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Tyrosinase (TYR) and tyrosinase-related proteins 1 and 2 (TYRP1 and TYRP2) are essential for pigmentation. They are generally classified as type-3 copper proteins, with binuclear copper active sites. Although there is experimental evidence f
Externí odkaz:
https://doaj.org/article/ba217f3439014ff892ecfb33883a13ee
Autor:
Di Wu, Hiromu Arakawa, Akiko Fujita, Hisashi Hashimoto, Masahiko Hibi, Kiyoshi Naruse, Yasuhiro Kamei, Chihiro Sato, Ken Kitajima
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Vertebrate CMP-sialic acid synthetase (CSS), which catalyzes the synthesis of CMP-sialic acid (CMP-Sia), consists of a 28 kDa-N-domain and a 20 kDa-C-domain. The N-domain is known to be a catalytic domain; however, the significance of the C-
Externí odkaz:
https://doaj.org/article/e0661301453f45079fe8ecf59607b6f8
Autor:
Seigo Katakura, Nobuaki Kobayashi, Hisashi Hashimoto, Chisato Kamimaki, Katsushi Tanaka, Sousuke Kubo, Kentaro Nakashima, Shuhei Teranishi, Saki Manabe, Keisuke Watanabe, Nobuyuki Horita, Yu Hara, Masaki Yamamoto, Makoto Kudo, Hongmei Piao, Takeshi Kaneko
Publikováno v:
Thoracic Cancer, Vol 11, Iss 10, Pp 2975-2982 (2020)
Background Advanced non‐small cell lung cancer (NSCLC) has a high mortality rate and poor prognosis. However, outcomes have gradually improved after the introduction of novel immunotherapies, including immune checkpoint inhibitors (ICIs). Although
Externí odkaz:
https://doaj.org/article/16617066622c41d597b7c6fc08914603
Autor:
Nobuaki Kobayashi, Hisashi Hashimoto, Chisato Kamimaki, Ryo Nagasawa, Katsushi Tanaka, Sousuke Kubo, Seigo Katakura, Hao Chen, Nobuyuki Hirama, Ryota Ushio, Ayako Aoki, Kentaro Nakashima, Shuhei Teranishi, Saki Manabe, Hiroki Watanabe, Nobuyuki Horita, Keisuke Watanabe, Yu Hara, Masaki Yamamoto, Makoto Kudo, Hongmei Piao, Takeshi Kaneko
Publikováno v:
Thoracic Cancer, Vol 11, Iss 8, Pp 2125-2129 (2020)
Introduction As most patients with epidermal growth factor receptor (EGFR)‐mutant non‐small cell lung cancer (NSCLC) develop progressive disease after treatment with osimertinib, it is important to develop more effective treatment options. Afatin
Externí odkaz:
https://doaj.org/article/087b6fea136f41399c90d1366b3a7289
Publikováno v:
IEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences. :294-305
Autor:
Atyaf Hamied, Qusay Alnedawy, Ana Correia, Christian Hacker, Mark Ramsdale, Hisashi Hashimoto, Tetsuhiro Kudoh
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101674- (2020)
Summary: The Arabian killifish, Aphanius dispar, is a small tropical teleost fish living in wide range of habitats in sea water and fresh water in the Middle East. Here, we report extraordinary fluorescent pigment cells in the Arabian killifish embry
Externí odkaz:
https://doaj.org/article/529e8c0711bc48efaf8f7795b2c6f6ac
Highly efficient generation of knock-in transgenic medaka by CRISPR/Cas9-mediated genome engineering
Autor:
Ikuko Watakabe, Hisashi Hashimoto, Yukiko Kimura, Saori Yokoi, Kiyoshi Naruse, Shin-ichi Higashijima
Publikováno v:
Zoological Letters, Vol 4, Iss 1, Pp 1-11 (2018)
Abstract Background Medaka (Oryzias latipes) is a popular animal model used in vertebrate genetic analysis. Recently, an efficient (~ 30%) knock-in system via non-homologous end joining (NHEJ) was established in zebrafish using the CRISPR/Cas9 system
Externí odkaz:
https://doaj.org/article/37fe058b39104a1da5a741b3f1bbd9ab
Autor:
Manfred Schartl, Susanne Schories, Yuko Wakamatsu, Yusuke Nagao, Hisashi Hashimoto, Chloé Bertin, Brigitte Mourot, Cornelia Schmidt, Dagmar Wilhelm, Lazaro Centanin, Yann Guiguen, Amaury Herpin
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-17 (2018)
Abstract Background Sex determination relies on a hierarchically structured network of genes, and is one of the most plastic processes in evolution. The evolution of sex-determining genes within a network, by neo- or sub-functionalization, also requi
Externí odkaz:
https://doaj.org/article/d2e711a503d541508902dfa7584ed90c
Autor:
Ayako Aoki, Yu Hara, Koji Okudela, Yoshihiro Ishikawa, Kosei Doshita, Hisashi Hashimoto, Kentaro Nakashima, Nobuyuki Horita, Nobuaki Kobayashi, Takeshi Kaneko
Publikováno v:
Thoracic Cancer, Vol 11, Iss 11, Pp 3407-3408 (2020)
Abstract A 77‐year‐old man who had a persistent productive cough for one month was admitted to our hospital. Chest computed tomography (CT) revealed subpleural nodular opacities, irregular pleural thickening with bilateral basal predominance, and
Externí odkaz:
https://doaj.org/article/2044d1cdade848ab9adbbf42bbe2adf8
Publikováno v:
Pigment Cell & Melanoma Research.