Výsledky vyhledávání - "Hisao Takeyama"

Acetylcholine-induced phosphorylation of CPI-17 in rat bronchial smooth muscle: the roles of Rho-kinase and protein kinase C

Autor: Hisao Takeyama, Hiroyasu Sakai, Tomona Hirano, Yoshihiko Chiba, Miwa Misawa

Publikováno v: Canadian Journal of Physiology and Pharmacology. 83:375-381

It has been demonstrated that CPI-17 provokes an inhibition of myosin light chain phosphatase to increase myosin light chain phosphorylaton and Ca2+sensitivity during contraction of vascular smooth muscle. However, expression and agonist-mediated reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627b1d27a4a4a7455dde7497bd7f63d4
https://doi.org/10.1139/y05-022

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Effects of Y-27632 on acetylcholine-induced contraction of intact and permeabilized intrapulmonary bronchial smooth muscles in rats

Autor: Miwa Misawa, Hisao Takeyama, Yoshihiko Chiba, Hiroyasu Sakai

Publikováno v: European Journal of Pharmacology. 427:77-82

In the present study, the effects of a selective Rho-associated coiled-coil forming protein kinase (ROCK) inhibitor, Y-27632 [(+)-(R)-trans-4-(1-aminoethyl)-(4-pyridyl)cyclohexanecarboxamide dihydrochloride] on acetylcholine-induced contraction and C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b7b8f655895d1444595c527b20c8b4
https://doi.org/10.1016/s0014-2999(01)01225-0

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Involvement of RhoA-mediated Ca2+ sensitization in antigen-induced bronchial smooth muscle hyperresponsiveness in mice

Autor: Yoshihiko Chiba, Hiroyasu Sakai, Ayako Ueno, Miwa Misawa, Hisao Takeyama, Koji Shinozaki, Shuji Nakazawa

Publikováno v: Respiratory Research, Vol 6, Iss 1, p 4 (2005)
Respiratory Research

Background It has recently been suggested that RhoA plays an important role in the enhancement of the Ca2+ sensitization of smooth muscle contraction. In the present study, a participation of RhoA-mediated Ca2+ sensitization in the augmented bronchia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad423da4e052be57e8293c5a9333fa1
https://doi.org/10.1186/1465-9921-6-4

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Acetylcholine-induced smooth muscle contraction of intrapulmonary small bronchi is augmented in antigen-induced airway hyperresponsive rats

Autor: Yuka Takada, Hisao Takeyama, Yoshihiko Chiba, Miwa Misawa, Hiroyasu Sakai

Publikováno v: Japanese journal of pharmacology. 84(2)

Smooth muscle responsiveness of intrapulmonary small bronchi obtained from repeatedly antigen-challenged rats was compared with that from control animals to determine whether smooth muscle contractility of peripheral airways is augmented by such repe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758bc5ff967d6eadbe6d171746d43bcd
https://pubmed.ncbi.nlm.nih.gov/11128046

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