Výsledky vyhledávání - "Hisao Kawakatsu"

Multiple organ toxicity, including hypochromic anemia, following repeated dose oral administration of phenobarbital (PB) in rats

Autor: Akiko Enomoto, Junya Sasaki, Hisao Kawakatsu, Tadashi Kosaka, Machiko Saka, Toshinori Yoshida, Katsumi Ishizuka, Sayuri Kojima, Nobuaki Nakashima, Mariko Tomita, Takanori Harada

Publikováno v: The Journal of Toxicological Sciences. 34:527-539

A 4-week repeated dose oral toxicity study of phenobarbital (PB) sodium was conducted in F344 rats of both sexes at PB doses of 0.8, 8, and 80 mg/kg/day to fully elucidate its general toxicity including hematological changes. Both sexes in the 80 mg/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383031f9433eaf853361959f3c1707a8
https://doi.org/10.2131/jts.34.527

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Prenatal developmental toxicity studies of 1,1,1-trichloro-2,2-bis(4-methoxyphenyl)ethane (methoxychlor) in rats and rabbits

Autor: Hiromi Kushida, Hisao Kawakatsu, Hiroaki Aoyama, Ken L. Takahashi, Masayuki Kikuta, Hitoshi Hojo, Shoji Teramoto, N. Shimizu

Publikováno v: Congenital Anomalies. 41:329-337

The studies were conducted in rats and rabbits to elucidate the potential developmental toxicity of methoxychlor in general accordance with the improved Japanese MAFF guidelines (12-Nousan-No. 8147, 2–1–18, 2000). Methoxychlor dissolved in corn o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae34b9463632620954f5a33cf170dc64
https://doi.org/10.1111/j.1741-4520.2001.tb00843.x

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Prenatal developmental toxicity studies of 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (p, p‘-DDT) in rats and rabbits

Autor: Hiroaki Aoyama, Hitoshi Hojo, Hiromi Kushida, Shoji Teramoto, Masayuki Kikuta, Koichi Ebino, Hisao Kawakatsu, Ken L. Takahashi, N. Shimizu

Publikováno v: Congenital Anomalies. 41:321-328

The studies were conducted in rats and rabbits to elucidate the potential developmental toxicity of p, p'-DDT in general accordance with the improved Japanese MAFF guidelines (12-Nousan-No. 8147,2–1–18, 2000). p, p'-DDT suspended in 1% aqueous so

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0ce89d865ea083196093903f99ad1880
https://doi.org/10.1111/j.1741-4520.2001.tb00842.x

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Isolated airway exposure to toluene diisocyanate results in skin sensitization

Autor: Koichi Ebino, Yasufumi Shutoh, Eiko Nagayoshi, Meryl H. Karol, Hideo Ueda, Hisao Kawakatsu, Tadashi Kosaka, Ranulfo Lemus

Publikováno v: Toxicology Letters. 121:79-85

Toluene diisocyanate (TDI), a highly reactive industrial chemical is a leading cause of occupational asthma in westernized countries. It has also been reported to be a skin sensitizer in mice and guinea pigs although instances of skin sensitivity in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf898d3caa7e3b2897d298c407fe717
https://doi.org/10.1016/s0378-4274(01)00325-3

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A repeated dose 90-day oral toxicity study of cyflumetofen,a novel acaricide, in rats

Autor: Nobuaki Nakashima, Machiko Saka, Koichi Ebino, Takanori Harada, Hisao Kawakatsu, Toshinori Yoshida, Sayuri Kojima, Yukiko Takeuchi, Yuko Chiba, Naoki Ikemi

Publikováno v: The Journal of toxicological sciences. 37(1)

Cyflumetofen is a novel acaricide which is highly active against phytophagous mites. As a part of safety assessment, a repeated dose 90-day oral toxicity study of cyflumetofen was conducted in Fischer (F344/DuCrj) rats of both sexes. Technical grade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::698870e302b7edb87df0a7ee71b16092
https://pubmed.ncbi.nlm.nih.gov/22293414

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