Výsledky vyhledávání - "Hisao Iwagami"

Synthesis of 2′,3′-Dideoxypurinenucleosides via the Palladium Catalyzed Reduction of 9-(2,5-Di-O-acetyl-3-bromo-3-deoxy-β-d-xylofuranosyl)purine Derivatives

Autor: Hiroshi Shiragami, Masayuki Arai, Toshihide Yukawa, Y. Amino, Kunisuke Izawa, Yutaka Honda, Yasuhiro Tanaka, Hisao Iwagami

Publikováno v: Nucleosides and Nucleotides. 15:31-45

Practical method to produce 2′,3′-dideoxypurinenucleosides from 9-(2,5-di-O-acetyl-3-bromo-3-deoxy-β-D-xylofuranosyl)purines (1) was developed. High ratio of 2′,3′-dideoxynucleoside to 3′-deoxyribonucleoside was obtained by selecting the r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3907895b99a020dc2f217877e6d47830
https://doi.org/10.1080/07328319608002368

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ChemInform Abstract: Synthesis of 2′,3′-Dideoxypurinenucleosides via the Palladium Catalyzed Reduction of 9-(2,5-Di-O-acetyl-3-bromo-3-deoxy-β-D- xylofuranosyl)purine Derivatives

Autor: Yutaka Honda, Hiroshi Shiragami, Y. Amino, Toshihide Yukawa, Kunisuke Izawa, Masayuki Arai, Yasuhiro Tanaka, Hisao Iwagami

Publikováno v: ChemInform. 27

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52393e9018561eb7adc1dd867ec18888
https://doi.org/10.1002/chin.199627242

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A Novel Method for the Synthesis of ddA and F-ddA Via Regioselective 2′-O-Deacetylation of 9-(2,5-DI-O-Acetyl-3-bromo-3-deoxy-β-D-xylofuranosyl)adenine

Autor: Toshihide Yukawa, Kunisuke Izawa, Yasuhiro Tanaka, Hiroshi Shiragami, Yumiko Uchida, Hisao Iwagami

Publikováno v: Nucleosides and Nucleotides. 11:391-400

Regioselective 2′-O-deacetylation of 9-(2,5-di-O-acetyl-3-bromo-3-deoxy-β-D-xylofuranosyl)adenine (1) is achieved by treatment of 1 with β-cyclodextrin (β-CyD) / aq. NaHCO3 or N2H4·H2O / EtOH. The 9-(5-O-Acetyl-3-bromo-3-deoxy-β-D-xylo-furanos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71cba4f4be553f9f93b8981cb4e21c78
https://doi.org/10.1080/07328319208021713

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Synthesis of a Chiral α-(Aminooxy)arylacetic Ester. II. A Route through a Chiral 2-Hydroxy-2-phenylacetic Acid Derivative

Autor: Masakazu Nakazawa, Masanobu Yatagai, Haruo Orita, Yutaka Honda, Toshihide Yukawa, Takashi Ohnuki, Hisao Iwagami

Publikováno v: Bulletin of the Chemical Society of Japan. 64:175-182

A simple and practical synthetic route has been developed for the synthesis of a chiral α-(aminooxy) ester (S)-16, which is a synthetic intermediate for a potent antipseudomonal cephalosporin antibiotic M-14659. In this synthetic route, the key inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0d042c6af0c17ea2f989bf67c287413
https://doi.org/10.1246/bcsj.64.175

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Novel method for the synthesis of 2',3'-unsaturated nucleosides from 2'(3')-acetoxy-3'(2')-halogeno derivatives by using sodium dithionite with viologen as a reductive elimination mediator

Autor: Hisao Iwagami, Yusuke Amino

Publikováno v: Chemical and Pharmaceutical Bulletin. 39:622-625

Reductive elimination of vicinal acetylated halohydrins with Na 2 S 2 O 4 as the reducing agent and viologen as the reduction mediator in a two-phase water-organic system is described. 2',3'-Unsaturrated nucleosides such as 1-(5-O-acetyl-2,3-dideoxy-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7d4af14505f67669fa8943d73350ba9d
https://doi.org/10.1248/cpb.39.622

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Synthesis of a Chiral α-(Aminooxy)arylacetic Ester. I. A Route through Optical Resolution of a Racemic α-(Phthalimidooxy)arylacetic Acid

Autor: Yutaka Honda, Hirokazu Naora, Masakazu Nakazawa, Hisao Iwagami, Toyoto Hijiya, Takashi Ohnuki, Toshihide Yukawa, Masanobu Yatagai

Publikováno v: Bulletin of the Chemical Society of Japan. 63:3073-3081

A synthetic route has been developed to the synthesis of a chiral O-alkyloxime (S)-16, which can be a synthetic intermediate for a potent antipsedomonal cephalosporin antibiotic M-14659 (1). The oxime moiety in (S)-16 has a chiral center at the carbo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aee6541f0ca2c2d148e919f71cb759cf
https://doi.org/10.1246/bcsj.63.3073

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