Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hisao Hatakeyama"'
Publikováno v:
Drug Development Research. 30:62-71
The thromboxane A, (TXA,) receptor antagonist, S-1452, calcium salt of a sterose- lectively synthesized d-enantiomer of the racemate 5-145, calcium 5(Z)-1 R,2S,3S,4S-7-(3-phenyl- sulfonylaminobicyclo(2.2.1) hept-2-yll-5-heptenoate di hydrate, was exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4cf769095016f45fd49d20137c3c629
https://doi.org/10.1002/ddr.430300204
https://doi.org/10.1002/ddr.430300204
Autor:
Hisato Kakushi, Kiyohisa Uchida, Nobuhiro Haga, Tatsuo Tsuri, Takeaki Matsui, Sanji Hagishita, Susumu Kamata, Kimio Takahashi, Atsushi Kurosawa, Hisao Hatakeyama
Publikováno v:
Chemical and Pharmaceutical Bulletin. 40:85-95
In a continuing effort to obtain more potent platelet activating factor (PAF) antagonists, we tried to synthesize a series of PAF-sulfonamide isosteres in which the substituent at the 2-position was modified to an acetoxy equivalent other than the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f004b35818c5defa3100fa885312ec8
https://doi.org/10.1248/cpb.40.85
https://doi.org/10.1248/cpb.40.85
Publikováno v:
Japanese Journal of Pharmacology. 50:195-205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e00d0225637d1575a0402e246471cdb
https://doi.org/10.1016/s0021-5198(19)42472-4
https://doi.org/10.1016/s0021-5198(19)42472-4
Autor:
Kazuyuki Sasakura, Hirokuni Joyama, Hisao Hatakeyama, Tatsuro Toyoda, Katsumi Hirose, Kentaro Hirai, Hirohiko Sugimoto, Toshio Fujishita, Yuji Tsukinoki, Teruyuki Ishiba
Publikováno v:
Journal of medicinal chemistry. 23(7)
A series of noval peptidoaminobenzophenones has been prepared via several routes and was evaluated for CNS activity. The structure--activity relationships in the series are discussed. In general, dipeptido-N-methylaminobenzophenones showed higher act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fbbf3420b5c44258f2de796797f299
https://pubmed.ncbi.nlm.nih.gov/7190614
https://pubmed.ncbi.nlm.nih.gov/7190614
Autor:
Akira Touchi, Hisao Hatakeyama, Hirokuni Jyoyama, Shigemi Otsubo, Takashi Matsubara, Katsumi Hirose
Publikováno v:
Nihon yakurigaku zasshi. Folia pharmacologica Japonica. 92(4)
Effect of the nonsteroidal anti-inflammatory drug 480156-S on liver drug-metabolizing activity was studied in rats, and its effect was compared with that of cimetidine. Cytochrome P-450-dependent 7-alkoxycoumarin O-dealkylase activity was not affecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5739be77a684816d2e94fe6846039cc6
https://pubmed.ncbi.nlm.nih.gov/3266606
https://pubmed.ncbi.nlm.nih.gov/3266606
Publikováno v:
Japanese Journal of Pharmacology. 46:281
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b8634ada5b140d68d5b9b245b1876b9
https://doi.org/10.1016/s0021-5198(19)57684-3
https://doi.org/10.1016/s0021-5198(19)57684-3
Autor:
Masami Eigyo, Fujio Asanuma, Hirokuni Jyoyama, Katsumi Hirose, Hisao Hatakeyama, Yasuyoshi Kojima
Publikováno v:
Japanese Journal of Pharmacology. 33:211
In terms of anti-inflammatory activity in acute and chronic animal models, 2-[4-(2-thiazolyloxy)-phenyl]-propionic acid (480156-S) was more active than Ibuprofen but inferior to indomethacin. The analgesic activities of 480156-S measured by the writh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f50729be3e205bfc9d4e187da6c2694
https://doi.org/10.1016/s0021-5198(19)60555-x
https://doi.org/10.1016/s0021-5198(19)60555-x
Autor:
Masafumi, Fujimoto, Shin′ichiro, Hashimoto, Shirō, Takahashi, Katsumi, Hirose, Hisao, Hatakeyama, Tadashi, Okabayashi
Publikováno v:
In Biochemical Pharmacology 1984 33(10):1645-1651