Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Hisako Sakiyama"'
Autor:
Kazuko Kuriiwa, Riako Masuda, Naokazu Inoue, Koichi Nakagawa, Kazuko Yoshida, Katusi Yamamoto, Hisako Sakiyama
Publikováno v:
Journal of Bone and Mineral Metabolism. 19:220-227
Osteoclasts differentiate from hematopoietic precursors of the monocyte/macrophage lineage to mononuclear preosteoclasts and multinuclear mature osteoclasts. In the present study, we report on the establishment of macrophage like cell lines from mous
Autor:
Naoki Itano, Riako Masuda, Naokazu Inoue, Koji Kimata, Takeshi Yamada, Koichi Nakagawa, Hisako Sakiyama, Kazuko Kuriiwa, Toshiyuki Saito, Yuki Takada
Publikováno v:
Cell and Tissue Research. 298:317-325
Ultrastructural aspects of hypertrophic chondrocytes in hamster and mouse epiphysial cartilage were examined in relation to their metabolic activities. With the hypertrophic change, cytoplasmic vacuolization proceeded leaving the partially intact end
Autor:
Riako Masuda, Kiichiro Yamaguchi, Toyomitsu Tsuchida, Hisako Sakiyama, Toru Toyoguchi, Hideshige Moriya, Koichi Nakagawa
Publikováno v:
Annals of the Rheumatic Diseases. 58:175-181
OBJECTIVE—The first complement component C1s was reported to have novel functions to degrade matrix components, besides its activities in the classic complement pathway. This study explores participation of C1s in articular cartilage degradation in
Publikováno v:
Human Genetics. 103:415-418
The complement system plays an important role in defense mechanisms by promoting the adherence of microorganisms to phagocytic cells and lysis of foreign organisms. Deficiencies of the first complement components, C1r/C1s, often cause systemic lupus
Autor:
Kazuko Kuriiwa, Shinobu Imajoh-Ohmi, Yasunori Okada, Hideshige Moriya, Toyomitsu Tsuchida, Koichi Nakagawa, Hisako Sakiyama, Kazushi Imai
Publikováno v:
Cell and Tissue Research. 288:557-565
The secondary ossification center of 14- to 16-day-old hamster tibiae was examined immunohistochemically with active and inactive Cls-specific antibodies, RK5 and RK4, respectively. At the ossification center, chondrocytes differentiate from prolifer
Autor:
Munehiro Nishida, Norie Sakai, Takashi Saito, Ken Nagino, Shinobu Imajoh-Ohmi, Shoichiro Miyatake, Hisako Sakiyama
Publikováno v:
International Journal of Cancer. 66:768-771
We have previously shown that non-transformed mouse A31 cells became tumorigenic when they were transfected with hamster C1s cDNA expression plasmid BCMGSNeoCS. In the present study, mutations were introduced into the cDNA at the activation cleavage
Publikováno v:
Journal of Biological Chemistry. 271:14636-14641
GM-95, a mutant cell line derived from mouse melanoma MEB-4 cells, is deficient in glycosphingolipids (GSLs) due to the lack of ceramide glucosyltransferase-1 activity (Ichikawa, S., Nakajo, N., Sakiyama, H., and Hirabayashi, Y. (1994) Proc. Natl. Ac
Publikováno v:
Proceedings of the National Academy of Sciences. 93:4638-4643
We have isolated a cDNA encoding human ceramide glucosyltransferase (glucosylceramide synthase, UDP-glucose:N-acylsphingosine D-glucosyltransferase, EC 2.4.1.80) by expression cloning using as a recipient GM-95 cells lacking the enzyme. The enzyme ca
Autor:
Kiichiro Yamaguchi, Norio Kato, Shigeharu Nagasawa, Mayumi Kusunoki, Hisako Sakiyama, Toru Toyoguchi, Hideshige Moriya, Hajime Kageyama, Shigeru Sakiyama, Shinobu Imajoh-Ohmi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1250:90-96
Hamster complement C1s cDNA was inserted into expression plasmid BCMGSNeo, and transfected to SEA7 cells, A31 mouse fibroblasts transformed by polyoma virus. The transfectant secreted a large amount of recombinant C1s that was activated in the serum
Autor:
Hiroshi Ohtsu, Yasunori Okada, Noriyuki Inaba, Toru Toyoguchi, Misako Matsumoto, Hideshige Moriya, Hisako Sakiyama
Publikováno v:
Cell & Tissue Research. 277:239-245
The first component of complement \(C\bar 1s\) has been shown to degrade type I and type II collagens (Yamaguchi et al. 1990), the latter of which is a major constituent of the cartilage matrix. In order to understand the physiological roles of \(C\b