Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Hisako Fujimura"'
Autor:
Takatsugu Ishikawa, Hisako Fujimura, Hiroshi Fukasawa, Ryo Hashimoto, Qinghua He, Yuki Honda, Takahiro Iwata, Shun Kaida, Jirohta Kasagi, Atsushi Kawano, Shuzo Kuwasaki, Kazushige Maeda, Shin’ichi Masumoto, Manabu Miyabe, Fusashi Miyahara, Kei’ichi Mochizuki, Norihito Muramatsu, Akihiko Nakamura, Ken’ichi Nawa, Yuki Obara, Shoei Ogushi, Yasuyuki Okada, Yoshihito Onodera, Kyoichiro Ozawa, Yasunobu Sakamoto, Mamoru Sato, Hajime Shimizu, Hiroyuki Sugai, Koutaku Suzuki, Yasuhisa Tajima, Shin’ichiro Takahashi, Yusuke Taniguchi, Yusuke Tsuchikawa, Hirohito Yamazaki, Ryuji Yamazaki, Hiroshi Y. Yoshida
Publikováno v:
Proceedings of the 24th International Spin Symposium (SPIN2021).
Publikováno v:
Journal of Applied Toxicology. 36:1259-1267
This study was conducted to investigate the use of a nanosuspension for intravenous injection into dogs to increase exposure without toxic additives for preclinical studies in the discovery stage. Nanosuspensions were prepared with a mixer mill and z
Publikováno v:
Chemical and Pharmaceutical Bulletin. 62:1073-1082
The present study aimed to develop a practical method for preparing nanosuspension formulations of poorly water-soluble compounds for enhancing oral absorption in toxicology studies in the discovery stage. To obtain a suitable nanosuspension formulat
Autor:
Eisuke Kume, Kazuyuki Kitamura, Tetsuya Sakairi, Jiro Sugimoto, Kimimasa Takahashi, Hiroko Sato, Hisako Fujimura
Publikováno v:
Experimental and Toxicologic Pathology. 65:457-462
Abnormality in hematological condition including hemolytic disorders has been suggested one of the risk factor of pulmonary thrombosis. We previously reported that phenylhydrazine (PHZ) could induce acute thrombosis in the rat lung. In this study, ti
Publikováno v:
Journal of applied toxicology : JAT. 36(10)
This study was conducted to investigate the use of a nanosuspension for intravenous injection into dogs to increase exposure without toxic additives for preclinical studies in the discovery stage. Nanosuspensions were prepared with a mixer mill and z
Publikováno v:
Journal of Applied Toxicology. 29:356-363
To evaluate new drugs' potential for hepatosteatosis, we developed a cell-based assay using a fluorescent fatty acid analog: BODIPY558/568 C12. Rat primary hepatocytes were exposed to positive reference compounds [cyclosporine A (CsA), clofibrate (CF
Publikováno v:
Progress of Theoretical Physics Supplement. 168:123-126
We have carried out the hyperon photo‐production experiment on the energy range of 1.5 to 2.4 GeV to study the properties of Λ*(1405) hyperon through the Λ*(1405) lineshapes in terms of the π+Σ− and π−Σ+ decay channels. To obtain clear ev
Autor:
Mamoru Fujiwara, Hisako Fujimura
Publikováno v:
Modern Physics Letters A. 21:2411-2417
Spin-isospin excitations in 13 N have been studied by means of the (3 He ,t) and (3 He ,tp) reactions at the bombarding energy of E(3 He ) = 450 MeV . The zero-degree (3 He ,t) spectrum is found to be similar to those from the (p,n) reactions at inte
Publikováno v:
Chemicalpharmaceutical bulletin. 62(11)
The present study aimed to develop a practical method for preparing nanosuspension formulations of poorly water-soluble compounds for enhancing oral absorption in toxicology studies in the discovery stage. To obtain a suitable nanosuspension formulat
Autor:
Yukito Ishizuka, Hisako Fujimura, Masahito Itoh, Chinami Aruga, Wataru Toriumi, Kunio Doi, Kaori Takahashi, Kazuyuki Kitamura, Eisuke Kume, Satoko Miwa
Publikováno v:
Experimental and Toxicologic Pathology. 56:235-244
Streptozotocin (SZ) is known to exert toxic effects not only on pancreatic islet beta cells but also on other organs including liver. For analyzing changes in genes expression associated with SZ toxicity, we performed DNA microarray analyses on the l