Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Hisakazu Iwai"'
Autor:
Yoshiyuki Suzuki, Yoshiyasu Karino, Hisakazu Iwai, Masakazu Uejima, Hiroshi Aikata, Eiji Suzuki, Fumitaka Suzuki, Kazuaki Chayama, Hiromitsu Kumada, Hitoshi Yoshiji
Publikováno v:
Hepatology Research. 48:1178-1183
Aim A novel jelly lactulose preparation (SK-1202) has been developed to improve compliance and reduce the elevation of blood glucose levels in diabetic patients. To compare the equivalence in the efficacy and safety of SK-1202 and an approved commerc
Publikováno v:
Journal of Gastroenterology
Background Clinical evidence of lactulose for chronic constipation in Japan was lacking. We performed a randomized, double-blind, placebo-controlled, dose-finding study in Japanese patients with chronic constipation to estimate the optimal clinical d
Autor:
Hitoshi, Yoshiji, Yoshiyasu, Karino, Yoshiyuki, Suzuki, Fumitaka, Suzuki, Masakazu, Uejima, Hiroshi, Aikata, Kazuaki, Chayama, Hisakazu, Iwai, Eiji, Suzuki, Hiromitsu, Kumada
Publikováno v:
Hepatology research : the official journal of the Japan Society of Hepatology. 48(13)
A novel jelly lactulose preparation (SK-1202) has been developed to improve compliance and reduce the elevation of blood glucose levels in diabetic patients. To compare the equivalence in the efficacy and safety of SK-1202 and an approved commerciall
Autor:
Makiko Motoi-Ohtsuji, Hisakazu Iwai, Kunihiro Ohta, Jun Katagi, Tadayoshi Ueda, Motoharu Kakiki, Takuo Ogihara, Takuya Nagao, Sho Tanaka, Kumiko Kusumoto, Norihito Matsumoto, Daichi Nagai, Hiroshi Arakawa, Takako Ohkura, Shinya Kaneda, Emiko Ozeki, Tomoko Jomura, Yukiko Inoue
Publikováno v:
Fundamental Toxicological Sciences. 2:41-48
Autor:
Tadayoshi Ueda, Hisakazu Iwai, Takeshi Ikeya, Takuo Ogihara, Takuya Nagao, Naoki Takahashi, Yukiko Inoue, Hiroshi Arakawa, Kumiko Kusumoto, Kazushi Naitoh, Emiko Ozeki, Kunihiro Ohta, Takako Ohkura, Kazuki Wada, Akiko Koeda, Tomoko Jomura
Publikováno v:
Drug metabolism and pharmacokinetics. 29(5)
We investigated the utility of three-dimensional (3D) spheroid cultures of human hepatocytes in discovering drug metabolites. Metabolites of acetaminophen, diclofenac, lamotrigine, midazolam, propranolol and salbutamol were analyzed by liquid chromat
Autor:
Toshihiko Kumazawa, Kiyoshi Haruyama, Shoji Fukushima, Yoshiaki Tagawa, Kazuhito Ichikawa, Hisakazu Iwai
Publikováno v:
Journal of Toxicologic Pathology. 13:7-11
To assess the morphological changes of the lacrimal gland after cholinergic suppression, we performed light- and transmission-electron microscopic examinations on the exorbital lacrimal glands in rats after intragastric intubation of atropine, a nons
Autor:
Toshihiko Kumazawa, Xiaozhong Yu, Ichihito Ichikawa, Zhelin Xie, Yasuhiro Takeuchi, Hidetaka Kondo, Tamie Nakajima, Shigetaka Shimodaira, Hisakazu Iwai, Nobuyuki Asaeda, Gaku Ichihara, Michihiro Kamijima
Publikováno v:
Journal of Occupational Health. 39:228-233
2-Bromopropane-Induced Hypoplasia of Bone Marrow in Male Rats: Tamie NAKAJIMA, et al. Department of Hygiene, Shinshu University School of Medicine—The hematotoxicity of 2 -bromo propane was investigated in thirty-six male Wistar rats. The rats were
Autor:
Katsuhiko Saito, Hikaru Seto, Wataru Fukushima, Shinji Kitazawa, Hisakazu Iwai, Hiroko Shojaku
Publikováno v:
Radiation medicine. 26(6)
The aim of this study was to investigate the frequency of breast tumors and breast cancers with noncontrast spiral chest computed tomography (CT). A clinical study was conducted to evaluate findings in the mammary region of 1008 consecutive patients
Autor:
Yutaka Mizushima, Masashi Kobayashi, Kazuhiko Sassa, Takashi Fujishita, Hisakazu Iwai, Satoshi Yasumura
Publikováno v:
Internal Medicine. 36:637-639
Diffuse parenchymal infiltrates in lower lung fields, right pleural effusion, multiple bronchial stenoses and hepatosplenomegaly were observed in a 30-year-old woman with iritis. Pleural effusion was a yellow exudate which was predominantly lymphocyt
Publikováno v:
The Journal of toxicological sciences. 25(3)
We examined the correlation between histopathological changes and porphyrin levels in the Harderian glands of male rats after treatment with atropine sulfate. After a single administration of atropine sulfate (250 mg/kg/day), the porphyrin levels in