Zobrazeno 1 - 10 of 101 pro vyhledávání: '"Hisaichi Fujii"'
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Akademický článek
Transgenic rescue of hemolytic anemia due to red blood cell pyruvate kinase deficiency
Autor: Hitoshi Kanno, Taiju Utsugisawa, Shin Aizawa, Tsutomu Koizumi, Ken-ichi Aisaki, Takako Hamada, Hiromi Ogura, Hisaichi Fujii
Publikováno v: Haematologica, Vol 92, Iss 6 (2007)
Background and Objectives Red blood cell pyruvate kinase (R-PK) deficiency is the most common glycolytic enzyme defect associated with hereditary non-spherocytic hemolytic anemia. Cases with the most severe deficiency die in the peri- or neonatal per
Externí odkaz: https://doaj.org/article/2a9ad33d09d540ddbb71ff21a845d02a
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2
Enhanced expression of myogenic differentiation factors and skeletal muscle proteins in human amnion-derived cells via the forced expression of MYOD1
Autor: Hiroaki Ohta, Hisaichi Fujii, Yoshika Akizawa, Yoshio Matsuda, Hideo Matsui, Yayoi Kawamichi, Kayoko Saito, Hitoshi Kanno
Publikováno v: Brain and Development. 35:349-355
Objectives: Mesenchymal stem cells are expected to be an ideal cell source for cellular and gene therapy. We previously showed that cells derived from the human placenta can be induced to differentiate into myotubes in vitro and to express dystrophin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7f8c383835666398adabf515282192
https://doi.org/10.1016/j.braindev.2012.05.012
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3
PYRUVATE SUPPLEMENTATION ENHANCES VASCULAR ENDOTHELIAL GROWTH FACTOR PRODUCTION BY BONE MARROW-DERIVED MONONUCLEAR CELLS
Autor: Hitoshi Kanno, Hiromi Ogura, Takako Aoki, Yuji Iribe, Hisaichi Fujii
Publikováno v: Japanese Journal of Transfusion and Cell Therapy. 58:26-32
1) Bone marrow‑derived mononuclear cells (BMMNC include endothelial progenitor cells (EPC which are character‑ ized by their secretion of angiogenic factors such as vascular endothelial growth factor (VEGF to recruit local endo‑ thelial cells t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::171a6d85529573958b0a63836948f2a4
https://doi.org/10.3925/jjtc.58.26
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4
High-dose chemotherapy followed by autologous and allogeneic peripheral blood stem cell transplantation for recurrent disseminated trilateral retinoblastoma
Autor: Hitoshi Kanno, Makiko Osawa, Katsuya Maebayashi, Osami Kubo, Hisaichi Fujii, Toshihisa Tsuruta, Masako Sakauchi, Yasuo Aihara, Yoshikazu Okada, Chikako Kiyotani
Publikováno v: Child's Nervous System. 27:1019-1024
Trilateral retinoblastoma (TRb) is an intracranial neurogenic tumor associated with unilateral or bilateral retinoblastoma and has very poor prognosis. Patients typically die from leptomeningeal tumor dissemination.A 3-year-old girl who had been diag
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d95d2388fdb96c881400edfbafa775
https://doi.org/10.1007/s00381-011-1419-8
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5
Shared molecular targets in pediatric gliomas and ependymomas
Autor: Toshihiko Murayama, Osami Kubo, Hisaichi Fujii, Masakazu Funase, Yoshikazu Okada, Makiko Osawa, Hitoshi Kanno, Yasuo Aihara, Toshihisa Tsuruta
Publikováno v: Pediatric Blood & Cancer. 57:1117-1123
Background Recent advances in multidisciplinary treatment approaches have improved the overall prognosis of pediatric brain tumors, but some patients remain refractory to treatment and do poorly. Several molecularly targeted therapies are under devel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::edf2c2b771ea4cd101d4dd96b4e3c5fe
https://doi.org/10.1002/pbc.23009
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6
Glycolytic inhibition by mutation of pyruvate kinase gene increases oxidative stress and causes apoptosis of a pyruvate kinase deficient cell line
Autor: Hisaichi Fujii, Ken-ichi Aisaki, Hitoshi Kanno, Jun Kanno, Shin Aizawa
Publikováno v: Experimental Hematology. 35:1190-1200
Objective SLC3 is a Friend erythroleukemic cell line established from the Pk-1 slc mouse, a mouse model of red blood cell type-pyruvate kinase (R-PK) deficiency. This study was aimed to elucidate the mechanisms attributing to apoptosis induced by R-P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2791b02d6afbdc24b78bf6bc2468f95
https://doi.org/10.1016/j.exphem.2007.05.005
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9
Molecular basis of Japanese variants of pyrimidine 5′-nucleotidase deficiency
Autor: Takenori Takizawa, Shiro Miwa, Hisaichi Fujii, Hitoshi Kanno
Publikováno v: British Journal of Haematology. 126:265-271
The type-I isoform of pyrimidine 5'-nucleotidase (P5N-I) has an important role in the catabolism of pyrimidine mononucleotides during erythroid maturation. Two alternatively spliced forms of P5N-I mRNA have been identified, and we found another alter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f528c6ed827c33024b5719a920123c4e
https://doi.org/10.1111/j.1365-2141.2004.05029.x
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10
A novel missense mutation (1060G → C) in thephosphoglycerate kinasegene in a Japanese boy with chronic haemolytic anaemia, developmental delay and rhabdomyolysis
Autor: Tomohiro Usuku, Shinsaku Imashuku, Hisaichi Fujii, Ikuyo Ueda, Shinjiro Todo, Gen Kano, Yoshiaki Hirashima, Kikuko Kuriyama, Akira Morimoto, Yasuko Sawai, Tohru Sugimoto, Hitoshi Kanno
Publikováno v: British Journal of Haematology. 122:1009-1013
We report the case of a 3-year-old Japanese boy with phosphoglycerate kinase 1 (PGK1) deficiency (Online Mendelian Inheritance in Man entry 311800). The patient had anaemia and jaundice at birth, necessitating exchange transfusions for 2 d. After one
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7275b6fb11735280cb36e34b28d09611
https://doi.org/10.1046/j.1365-2141.2003.04543.x
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