Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Hisae Karimata"'
Publikováno v:
Journal of the American Chemical Society. 131:16881-16888
Short RNA sequences exhibiting the activity of a target RNA cleavage are promising for cellular gene regulation and biosensor research, but the reaction media different from an aqueous solution may cause unanticipated molecular interactions and prope
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 26:589-595
Although water is an integral part of DNA structures, the effects of water molecules on various DNA structures which are formed by not only Watson-Crick but also Hoogsteen base pairs are still unclear. Here, we studied quantitatively the effects of m
Publikováno v:
Bulletin of the Chemical Society of Japan. 80:1987-1994
Although the thermodynamic stability of ordered DNA is known to be affected by interactions with cations and water molecules, there is scarce quantitative information about the behavior of DNA unde...
Publikováno v:
Angewandte Chemie International Edition. 44:3740-3744
Publikováno v:
Biochemistry. 44:7125-7130
DNA is a promising material for the construction of a biosensor or bioindicator because its structure is sensitive to the binding of cofactors. In the current studies, we found that a combination of two DNA oligonucleotides, 5'-TCTTTCTCTTCT-3' and 5'
Publikováno v:
Nucleic acids symposium series (2004). (52)
Although metal ion is essential for the DNA and RNA folding, there are a limited number of reports describing the influence of molecular environments on the metal ion binding. Here, we investigated the binding properties of Mg(2+) and Na(+) toward th
Autor:
Lei Wu, Hisae Karimata, Hiroshi Sakai, Toshimasa Kirihata, Satoshi Fujii, Naoki Sugimoto, Yuichi Sato, Hirohito Oka, Masayuki Kuwahara, Hiroaki Sawai, Shu-ichi Nakano
Publikováno v:
Molecular bioSystems. 4(6)
Water-soluble neutral cosolutes can be used to quantify biomolecular properties in the particular molecular environment occurring in a cell. We studied the conformation and the thermal stability of DNA and RNA structures in the presence of PEG [poly(
Publikováno v:
Scopus-Elsevier
We investigated molecular crowding effects on the thermodynamic stability of Hoogsteen and Watson-Crick base pairs in an intramolecular duplex and triplex. The melting temperature (Tm) of Hoogsteen base pair formations in the triplex and the duplex i
Publikováno v:
Journal of the American Chemical Society. 129(18)
Development of a guanine nanowire (G-wire) that is controllable and can be switched by external signals is important for the creation of molecular electronic technologies. Here, we constructed a G-wire in which the thymines of the main chain of d(G4T
Publikováno v:
Scopus-Elsevier
We designed and synthesized an artificial DNA that undergoes a structural transition induced by metal ions. A 2, 2'-bipyridine unit was incorporated into the main chain of d(G4T4G4) instead of thymine. Structural analyses of the artificial DNA with a