Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Hisaaki Miyoshi"'
Autor:
Tsutomu Masaki, Koji Murao, Yasuyuki Suzuki, Keiichi Okano, Takashi Himoto, Hirohito Mori, Hideyuki Kobara, Yuuichi Aritomo, Mitsuyoshi Kobayashi, Shima Mimura, Kei Nomura, Hisaaki Miyoshi, Joji Tani, Akira Kitanaka, Hisakazu Iwama, Jian Gong, Kiyohito Kato
Recent studies suggest that metformin, which is commonly used as an oral anti-hyperglycemic agent of the biguanide family, may reduce cancer risk and improve prognosis, but the mechanisms by which metformin affects various cancers, including gastric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c58e5f06f5a92ca0301df8378e99fc
https://doi.org/10.1158/1535-7163.c.6535704.v1
https://doi.org/10.1158/1535-7163.c.6535704.v1
Autor:
Tsutomu Masaki, Koji Murao, Yasuyuki Suzuki, Keiichi Okano, Takashi Himoto, Hirohito Mori, Hideyuki Kobara, Yuuichi Aritomo, Mitsuyoshi Kobayashi, Shima Mimura, Kei Nomura, Hisaaki Miyoshi, Joji Tani, Akira Kitanaka, Hisakazu Iwama, Jian Gong, Kiyohito Kato
PDF file - 87K, Metformin structure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49515fbce074e8c10713ed9edd00d5b5
https://doi.org/10.1158/1535-7163.22497735
https://doi.org/10.1158/1535-7163.22497735
Autor:
Asahiro Morishita, Reiji Haba, Joji Tani, Shintaro Fujihara, Hideki Kobara, Yasuyuki Suzuki, Noriko Nishiyama, Takashi Himoto, Tsutomu Masaki, Hirohito Mori, Koji Fujita, Teppei Sakamoto, Hisaaki Miyoshi, Keiichi Okano, Naoki Yamamoto, Hirohito Yoneyama, Hisakazu Iwama, Emi Ibuki, Takako Nomura
Publikováno v:
Oncology Letters
A 72-year-old female was referred for further evaluation of epigastralgia. Abdominal contrast computed tomography revealed numerous tumors in the two lobes of the liver. Liver biopsy and immunohistochemical staining revealed that the tumor cells were
Autor:
Keiichi Okano, Hisaaki Miyoshi, Yasuyuki Suzuki, Takashi Himoto, Teppei Sakamoto, Hisakazu Iwama, Tomoko Tadokoro, Asahiro Morishita, Miwako Watanabe, Hirohito Yoneyama, Akiko Katsura, Takako Nomura, Shima Mimura, Joji Tani, Koji Fujita, Kyoko Oura, Kayo Hirose, Tsutomu Masaki
Publikováno v:
International Journal of Molecular Medicine
Visceral adipose tissue contributes to the pathophysiology of metabolic syndrome. Metformin has been reported to suppress lipogenesis in a murine preadipocyte cell line. However, the effect of metformin on the differentiation of human visceral adipos
Autor:
Teppei Sakamoto, Hirohito Yoneyama, Takashi Himoto, Tsutomu Masaki, Asahiro Morishita, Koji Fujita, Shintaro Fujihara, Hisaaki Miyoshi, Joji Tani, Hisakazu Iwama
Publikováno v:
Oncology Letters
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-associated mortality worldwide. Although surgery is considered the most effective treatment for patients with HCC, its indication is restricted by limited criteria and a high r
Autor:
Fuyuko Kokado, Toshihiro Niki, Koji Fujita, Hisaaki Miyoshi, Hirohito Yoneyama, Takako Nomura, Keiko Fujikawa, Asahiro Morishita, Tomoko Tadokoro, Hideki Kobara, Hisakazu Iwama, Tsutomu Masaki, Jitsuko Takano, Shintaro Fujihara, Joji Tani, Hirohito Mori, Taiga Chiyo, Mitsuomi Hirashima, Teppei Sakamoto
Publikováno v:
Oncology Reports. 35:851-860
Gastric cancer is the second-leading cause of cancer-related mortality worldwide, and the prognosis of advanced gastric cancer remains poor. Galectin-9 (Gal-9) is a tandem-repeat-type galectin that has recently been demonstrated to exert anti-prolife
Autor:
Joji Tani, Hirohito Mori, Tae Matsunaga, Hirohito Yoneyama, Reiji Haba, Maki Ayaki, Seiko Kagawa, Takako Nomura, Tatsuo Yachida, Hisaaki Miyoshi, Emiko Maeda, Shintaro Fujihara, Tsutomu Masaki, Noriko Nishiyama, Asahiro Morishita, Takashi Himoto, Hideki Kobara, Teppei Sakamoto
Publikováno v:
Oncology Letters
Tissue sampling of primary duodenal lymphoma is essential for its histological diagnosis. Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA), which is frequently used for submucosal tumor (SMT)-like duodenal tumors, is adequate for cytolog
Autor:
Takashi Himoto, Yoshinao Muro, Hisaaki Miyoshi, Hirohito Yoneyama, Asahiro Morishita, Reiji Haba, Tsutomu Masaki, Kazumitsu Sugiura, Noriyo Tanaka, Joji Tani, Akiko Saito
Publikováno v:
Clinics and Research in Hepatology and Gastroenterology. 39:222-229
Summary Background Anticentromere antibodies (ACAs) have been observed in patients with autoimmune hepatitis (AIH) and hepatitis C virus (HCV)-related chronic liver disease (CLD-C) as well as those with primary biliary cirrhosis (PBC). However, littl
Autor:
Jitsuko Takano, Ryoichi Okura, Tsutomu Masaki, Yuka Yamana, Akiko Katsura, Takashi Himoto, Keiichi Okano, Shima Mimura, Hirohito Yoneyama, Hisaaki Miyoshi, Teppei Sakamoto, Yasuyuki Suzuki, Mitsuomi Hirashima, Asahiro Morishita, Emiko Maeda, Hisakazu Iwama, Kiyoyuki Kobayashi, Joji Tani, Toshiro Niki, Takako Nomura, Koji Fujita, Miwa Tatsuta
Publikováno v:
International Journal of Oncology. 46:2419-2430
Galectin-9, a soluble β-galactoside-binding animal lectin, evokes apoptosis in various human cancer cell lines. The galectin-9 antitumor effect against hepatocellular carcinoma (HCC) is, however, unknown. We investigated whether galectin-9 suppresse
Autor:
Keiichi Okano, Hirohito Mori, Noriko Nishiyama, Tsutomu Masaki, Kiyohito Kato, Yasuyuki Suzuki, Tomoko Nishioka, Hisakazu Iwama, Shintaro Fujihara, Asahiro Morishita, Mitsuyoshi Kobayashi, Hisaaki Miyoshi, Hideki Kobara, Taiga Chiyo
Publikováno v:
International Journal of Oncology. 46:2172-2180
Esophageal carcinoma is the eighth most common cancer worldwide and the sixth leading cause of cancer-related deaths, with one of the worst prognoses of any form of cancer. Treatment with the anti-diabetic drug metformin has been associated with redu