Výsledky vyhledávání - "Hisaaki Komaki"

Akademický článek

Elevated plasma progranulin levels in the acute phase are correlated with recovery of left ventricular function in the chronic phase in patients with acute myocardial infarction.

Autor: Shingo Minatoguchi, Atsushi Satake, Hirotaka Murase, Ryo Yoshizumi, Hisaaki Komaki, Shinya Baba, Shinji Yasuda, Shinsuke Ojio, Toshiki Tanaka, Hiroyuki Okura, Shinya Minatoguchi

Publikováno v: PLoS ONE, Vol 19, Iss 11, p e0313014 (2024)

BackgroundProgranulin is a secreted glycoprotein that regulates inflammation and wound healing. However, plasma progranulin levels in the acute phase and their clinical significance in patients with acute myocardial infarction (AMI) remain to be eluc

Externí odkaz: https://doaj.org/article/76e4975a65384482a724d61f5afc34d9

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Akademický článek

Excessively low salt diet damages the heart through activation of cardiac (pro) renin receptor, renin-angiotensin-aldosterone, and sympatho-adrenal systems in spontaneously hypertensive rats.

Autor: Chihiro Okamoto, Yuka Hayakawa, Takuma Aoyama, Hisaaki Komaki, Shingo Minatoguchi, Masamitsu Iwasa, Yoshihisa Yamada, Hiromitsu Kanamori, Masanori Kawasaki, Kazuhiko Nishigaki, Atsushi Mikami, Shinya Minatoguchi

Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0189099 (2017)

A high salt intake causes hypertension and leads to cardiovascular disease. Therefore, a low salt diet is now recommended to prevent hypertension and cardiovascular disease. However, it is still unknown whether an excessively low salt diet is benefic

Externí odkaz: https://doaj.org/article/bdad932bdaa44a639704feac13ba5bda

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Akademický článek

High salt intake damages the heart through activation of cardiac (pro) renin receptors even at an early stage of hypertension.

Autor: Yuka Hayakawa, Takuma Aoyama, Chiharu Yokoyama, Chihiro Okamoto, Hisaaki Komaki, Shingo Minatoguchi, Masamitsu Iwasa, Yoshihisa Yamada, Itta Kawamura, Masanori Kawasaki, Kazuhiko Nishigaki, Atsushi Mikami, Fumiaki Suzuki, Shinya Minatoguchi

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0120453 (2015)

It has not yet been fully elucidated whether cardiac tissue levels of prorenin, renin and (P)RR are activated in hypertension with a high salt intake. We hypothesized that a high salt intake activates the cardiac tissue renin angiotensin system and p

Externí odkaz: https://doaj.org/article/a770047c67a040a4bd57542b822e1846

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High-salt intake accelerates functional and histological renal damage associated with renal tissue overexpression of (pro)renin receptors and AT1 receptors in spontaneously hypertensive rats

Autor: Yoshihisa Yamada, Kazuhiko Nishigaki, Yuka Hayakawa, Shingo Minatoguchi, Hiromitsu Kanamori, Shinya Minatoguchi, Hisaaki Komaki

Publikováno v: Clinical and experimental nephrology. 24(7)

This study aimed to investigate the effect of combination of high-salt intake and hypertension on renal functional and histological damage, associated with renal (pro)renin receptor [(P)RR] and AT1 receptor in rats. Wistar Kyoto rats (WKYs) and spont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3d36f76c69a3da6b626a884f28dfef
https://pubmed.ncbi.nlm.nih.gov/32246289

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Azilsartan attenuates cardiac damage caused by high salt intake through the downregulation of the cardiac (pro)renin receptor and its downstream signals in spontaneously hypertensive rats

Autor: Masamitsu Iwasa, Chihiro Okamoto, Shinya Minatoguchi, Yoshihisa Yamada, Hisaaki Komaki, Masanori Kawasaki, Yuka Hayakawa, Shingo Minatoguchi, Kazuhiko Nishigaki, Hiromitsu Kanamori

Publikováno v: Hypertension Research. 41:886-896

We examined whether the stimulation of the angiotensin II AT1 receptor increases the expression of the cardiac (pro)renin receptor ((P)RR) and its downstream signals and whether the blockade of the angiotensin II AT1 receptor by azilsartan decreases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e76ad32c9ade091f3e9839432e5d78
https://doi.org/10.1038/s41440-018-0099-0

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Unusual manifestation of left ventricular electrical conduction delay on the surface 12-lead electrocardiogram in a patient with prior myocardial infarction

Autor: Hisaaki Komaki, Yuki Sahashi, Kazuhiko Nishigaki, Tomoki Kubota, Hiroyuki Okura, Takashi Nakashima, Nobuhiro Takasugi

Publikováno v: Journal of electrocardiology. 55

We describe a 41-year-old man with a prior history of myocardial infarction, whose surface 12-lead electrocardiogram did not show typical left bundle-branch block pattern or wide QRS complex. However, electrophysiological study showed distinct left v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74060ffa3c9459fec0f19345e494c36e
https://pubmed.ncbi.nlm.nih.gov/31078105

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High Salt Intake Damages the Heart through Activation of Cardiac (Pro) Renin Receptors Even at an Early Stage of Hypertension

Autor: Chihiro Okamoto, Yuka Hayakawa, Masamitsu Iwasa, Fumiaki Suzuki, Takuma Aoyama, Itta Kawamura, Masanori Kawasaki, Kazuhiko Nishigaki, Chiharu Yokoyama, Hisaaki Komaki, Yoshihisa Yamada, Atsushi Mikami, Shinya Minatoguchi, Shingo Minatoguchi

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0120453 (2015)

Objective It has not yet been fully elucidated whether cardiac tissue levels of prorenin, renin and (P)RR are activated in hypertension with a high salt intake. We hypothesized that a high salt intake activates the cardiac tissue renin angiotensin sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60b47be8ef80447f9015b279a1062407
http://europepmc.org/articles/PMC4370564

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