Assessment of brain-derived extracellular vesicle enrichment for blood biomarker analysis in age-related neurodegenerative diseases: An international overview.

Autor: Badhwar A; Département de pharmacologie et physiologie, Institut de Génie Biomédical, Faculté de Médecine, Université de Montréal, Montréal, Quebec, Canada.; Multiomics Investigation of Neurodegenerative Diseases (MIND) lab, Centre de recherche de l'Institut Universitaire de Gériatrie, Montréal, Quebec, Canada., Hirschberg Y; Centre for Proteomics, University of Antwerp, Antwerp, Belgium.; Health Unit, Flemish Institute for Technological Research (VITO), Mol, Belgium., Valle-Tamayo N; Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Calle San Quintí, Barcelona, Spain., Iulita MF; Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Calle San Quintí, Barcelona, Spain., Udeh-Momoh CT; Ageing Epidemiology research unit, School of Public Health, Imperial College London, London, UK.; Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Karolinska Institutet, Solna, Sweden.; Global Brain Health Institute, University of San Francisco Joan and Sanford I. Weill Neurosciences building, San Francisco, California, USA.; Imarisha Centre for Brain Health and Aging, Brain and Mind Institute, Aga Khan University, Nairobi, Kenya., Matton A; Ageing Epidemiology research unit, School of Public Health, Imperial College London, London, UK.; Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Karolinska Institutet, Solna, Sweden.; Division of Neurogeriatrics, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Karolinska Institutet, Solna, Nobels väg, Sweden., Tarawneh RM; Department of Neurology, Center for Memory and Aging, University of New Mexico, Albuquerque, New Mexico, USA., Rissman RA; VA San Diego Healthcare System, San Diego, California, USA.; Department of Physiology and Neuroscience, Alzheimer's Therapeutic Research Institute, Keck School of Medicine of the University of Southern California, San Diego, California, USA., Ledreux A; Department of Neurosurgery, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Winston CN; Department of Physiology and Neuroscience, Alzheimer's Therapeutic Research Institute, Keck School of Medicine of the University of Southern California, San Diego, California, USA., Haqqani AS; National Research Council Canada, Ottawa, Ontario, Canada.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Jul; Vol. 20 (7), pp. 4411-4422. Date of Electronic Publication: 2024 Jun 12.

Proteomic comparison between non-purified cerebrospinal fluid and cerebrospinal fluid-derived extracellular vesicles from patients with Alzheimer's, Parkinson's and Lewy body dementia.

Autor: Hirschberg Y; Health Unit, Flemish Institute for Technological Research (VITO), Mol, Belgium.; Centre for Proteomics (CfP), University of Antwerp, Antwerp, Belgium., Valle-Tamayo N; Department of Neurology, Sant Pau Memory Unit, Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Madrid, Spain., Dols-Icardo O; Department of Neurology, Sant Pau Memory Unit, Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Madrid, Spain., Engelborghs S; Department of Neurology and Bru-BRAIN, Universitair Ziekenhuis Brussel and NEUR Research Group, Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Brussels, Belgium.; Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Buelens B; Data Science Hub, Flemish Institute for Technological Research (VITO), Mol, Belgium., Vandenbroucke RE; VIB Center for Inflammation Research, VIB, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium., Vermeiren Y; Faculty of Medicine & Health Sciences, Translational Neurosciences, University of Antwerp, Antwerp, Belgium.; Division of Human Nutrition and Health, Chair Group of Nutritional Biology, Wageningen University & Research (WUR), Wageningen, The Netherlands., Boonen K; Health Unit, Flemish Institute for Technological Research (VITO), Mol, Belgium.; Centre for Proteomics (CfP), University of Antwerp, Antwerp, Belgium., Mertens I; Health Unit, Flemish Institute for Technological Research (VITO), Mol, Belgium.; Centre for Proteomics (CfP), University of Antwerp, Antwerp, Belgium.

Publikováno v: Journal of extracellular vesicles [J Extracell Vesicles] 2023 Dec; Vol. 12 (12), pp. e12383.

A phase II study of patients with advanced or metastatic renal cell carcinoma (mRCC) receiving pazopanib after previous checkpoint inhibitor treatment

Autor: Powles, Thomas, Oudard, S., Grünwald, Viktor, Calvo, E., Michaelson, M.D., Burotto, Mauricio, Melichar, Bohuslav, Tyagi, R., Hilmi, F., Gaur, Anushri, Hirschberg, Y., Heng, Dede Liana

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=unidue___bib::79a6a7c65f720f1b80745ea2e73b0858

Prospective Observational Study of Pazopanib in Patients with Advanced Renal Cell Carcinoma (PRINCIPAL Study)

Autor: Schmidinger, M. Bamias, A. Procopio, G. Hawkins, R. Sanchez, A.R. Vázquez, S. Srihari, N. Kalofonos, H. Bono, P. Pisal, C.B. Hirschberg, Y. Dezzani, L. Ahmad, Q. Jonasch, E. Gimeno, R.A. Herranz, U.A. Ardavanis, A. Ashraf, S.A. Bamias, A. Barone, C. Bella, S.R. Belz, H. Companario, E.B. Bolling, C. Bono, P. Bothe, K. Carteni, G. Espinosa, J.C. Clausse, M. Confente, C. Coskun, H. Herrero, G.C. Demey, W. D'hondt, R. Santasusana, M.D. Doshi, G. Elkiran, E. Facchini, G. Fein, L. Calvo, O.F. Flaherty, A. Fountzilas, G. Fruehauf, J. Díaz, E.G. Garcia, R. Domínguez, R.G. Ghosn, M. Glorieux, P. Goebell, P.J. Gutierrez, L.G.-A. Gonzalez, M. Green, N.B. Arnau, M.G. Harich, H.-D. Hawkins, R. Hegele, A. Pérez, C.H. Herrmann, E. Horniniger, W.J. Hutson, T.E. Janetschek, G. Kalantari, H. Kalofonos, H. Klausmann, M. Kolin, M. Krause, S. Kroening, H. Sorrosal, J.J.L. Lázaro, M. Lema, M. Lema, M.L. Lin, J. Lueck, A. Lybaert, W. Magi, A. Marina, V.A. Rey, J.P.M. Matus, G. Melear, J. Gonzalez, B.M. Milella, M. Montalar, J. Ferrandis, J.M. Nathan, P. Nechushtan, H. Nusch, A. Ojamaa, K. Oksuzoglu, B. Ozkan, M. Papazisis, K. Passalacqua, R. Pe'er, A. Gracia, J.L.P. Pichler, A. Pokker, H. Porta, C. Rauchenwald, M. Richardet, M.E. Richey, S.L. Garcia, J.M.R. Sánchez, A.R. Rudolph, R. Sabbatini, R. Salmon, J.-P. Lobera, C.S. Sarid, D.L. Saylors, G.B. Schmidinger, M. Schrijvers, D. Schulze, M. Sevilay, A. Shumaker, G.G. Siemer, S. de Prado y Otero, D.S. Srihari, N. Stoiber, F. Rodriguez, C.S. Varela, M.S. Vasanthan, S. Estevez, S.V. Vehling-Kaiser, U. Vogelzang, N. Weiss, H. Whenham, N. Wyendaele, W. Yildiz, R. Yucel, I. Zarba, J.J. Zarkar, A. Zhong, W. Ziem, P. the PRINCIPAL Study Group

Background: Real-world data are essential to accurately assessing efficacy and toxicity of approved agents in everyday practice. PRINCIPAL, a prospective, observational study, was designed to confirm the real-world safety and efficacy of pazopanib in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::bda22c7fecdbb1bce9c4b96b2639f928
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3077687

Real-World Evidence Study on the Long-Term Safety of Everolimus in Patients With Tuberous Sclerosis Complex: Final Analysis Results.

Autor: Ruiz-Falcó Rojas ML; Hospital Infantil Universitario Nino Jesus, Madrid, Spain., Feucht M; Universitäts-Klinik für Kinder-und Jugendheilkunde Wien, Vienna, Austria., Macaya A; Hospital Universitari Vall d' Hebron, Barcelona, Spain., Wilken B; Klinikum Kassel GmbH, Kassel, Germany., Hahn A; Abteilung Kinderneurologie, Universitätsklinikum Giessen und Marburg GmbH, Giessen, Germany., Maamari R; Novartis Pharmaceuticals Corporation, East Hanover, NJ, United States., Hirschberg Y; Novartis Pharmaceuticals Corporation, East Hanover, NJ, United States., Ridolfi A; Novartis Pharma S.A.S, Rueil-Malmaison, France., Kingswood JC; Royal Sussex County Hospital, Brighton, United Kingdom.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2022 Apr 08; Vol. 13, pp. 802334. Date of Electronic Publication: 2022 Apr 08 (Print Publication: 2022).