Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Hiroyuki Yajima"'
Autor:
Taku James Sairenji, Shinnosuke Masuda, Yuya Higuchi, Mitsue Miyazaki, Hiroyuki Yajima, Oh Kwan Ee, Yuki Fujiwara, Takuya Araki, Noriaki Shimokawa, Noriyuki Koibuchi
Publikováno v:
Endocrine Journal, Vol 71, Iss 7, Pp 661-674 (2024)
The placenta secretes a prolactin (PRL)-like hormone PRL3B1 (placental lactogen II), a luteotropic hormone essential for maintaining pregnancy until labor in mice. A report from 1984 examined the secretion pattern of PRL3B1 in prepartum mice. In the
Externí odkaz:
https://doaj.org/article/ec0d569a668e474c8b7b7354a2041603
Autor:
Yuji Takahashi, Ichizo Nishino, Madoka Mori-Yoshimura, Yasushi Oya, Satoru Noguchi, Hiroyuki Yajima, Katsuhiro Mizuno
Publikováno v:
BMJ Neurology Open, Vol 4, Iss 2 (2022)
Background A number of clinical trials targeting GNE myopathy patients have been conducted. However, useful clinical parameters for postmarketing surveillance and long-term clinical observation have not yet been established.Objective We conducted a 5
Externí odkaz:
https://doaj.org/article/e3ca44769b974df09a676a97da0b98b6
Autor:
Hirofumi Komaki, Yoshihiro Maegaki, Tsuyoshi Matsumura, Kazuhiro Shiraishi, Hiroyuki Awano, Akinori Nakamura, Satoru Kinoshita, Katsuhisa Ogata, Keiko Ishigaki, Shinji Saitoh, Michinori Funato, Satoshi Kuru, Takahiro Nakayama, Yasuyuki Iwata, Hiroyuki Yajima, Shin’ichi Takeda
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 2, Pp 181-190 (2020)
Abstract Objective Duchenne muscular dystrophy (DMD) is a progressive muscular disease characterized by chronic cycles of inflammatory and necrotic processes. Prostaglandin D2 (PGD2) is produced by hematopoietic PGD synthase (HPGDS), which is patholo
Externí odkaz:
https://doaj.org/article/001a1b84c3124cd5bcf321aa65fa9301
Autor:
Hiroyuki Yajima, Izuki Amano, Sumiyasu Ishii, Tetsushi Sadakata, Wataru Miyazaki, Yusuke Takatsuru, Noriyuki Koibuchi
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Thyroid hormone (TH) plays important roles in the developing brain. TH deficiency in early life leads to severe developmental impairment in the hippocampus. However, the mechanisms of TH action in the developing hippocampus are still largely unknown.
Externí odkaz:
https://doaj.org/article/749f0e21d14441258e8390b036f9428f
Autor:
Yuko Shimizu-Motohashi, Emiko Chiba, Katsuhiro Mizuno, Hiroyuki Yajima, Akihiko Ishiyama, Eri Takeshita, Noriko Sato, Mari Oba, Masayuki Sasaki, Shuichi Ito, Hirofumi Komaki
Publikováno v:
Brain and Development. 45:161-170
Real-world data have shown variability in treatment responses to nusinersen in spinal muscular atrophy (SMA). We investigated whether the magnitude of muscle impairment assessed by magnetic resonance imaging (MRI) at baseline can predict the treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7627e78d8a0ba928443647afb86caa4
https://doi.org/10.1016/j.braindev.2022.11.002
https://doi.org/10.1016/j.braindev.2022.11.002
Autor:
Junya Saito, Mio Yamashima, Toshiya Hayashida, Tomonari Ikeda, Satoshi Ishida, Tatsuki Urakawa, Takuma Okamura, Yasutaka Kuribayashi, Shinobu Yamamichi, Hiroyuki Yajima, Osamu Miyazaki, Tetsuro Honda, Ryuichi Sugiyama, Tomoko Kiyohara, Ryosuke Suzuki, Hiroyuki Moriuchi, Tatsuki Ichikawa
Publikováno v:
Kanzo. 63:500-503
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::012edae57b059bef40c2b0fc414990e2
https://doi.org/10.2957/kanzo.63.500
https://doi.org/10.2957/kanzo.63.500
Autor:
Natalie F, Reash, Meredith K, James, Lindsay N, Alfano, Anna G, Mayhew, Marni, Jacobs, Megan A, Iammarino, Scott, Holsten, Chikako, Sakamoto, Takayuki, Tateishi, Hiroyuki, Yajima, Tina, Duong, Brittney, de Wolf, Richard, Gee, Diana X, Bharucha-Goebel, Elena, Bravver, Madoka, Mori-Yoshimura, Kate, Bushby, Laura E, Rufibach, Volker, Straub, Linda P, Lowes
Publikováno v:
Muscle & Nerve. 66:159-166
Dysferlinopathy demonstrates heterogeneity in muscle weakness between patients, which can progress at different rates over time. Changing muscle strength due to disease progression or from an investigational product is associated with changing functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8bce32faed7890afe0a747f6670d31d
https://doi.org/10.1002/mus.27570
https://doi.org/10.1002/mus.27570
Autor:
Madoka Mori-Yoshimura, Hiroyuki Yajima, Yasushi Oya, Katsuhiro Mizuno, Satoru Noguchi, Ichizo Nishino, Yuji Takahashi
Publikováno v:
BMJ neurology open. 4(2)
BackgroundA number of clinical trials targeting GNE myopathy patients have been conducted. However, useful clinical parameters for postmarketing surveillance and long-term clinical observation have not yet been established.ObjectiveWe conducted a 5-y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075bb86aacca134c7d9e820cf24887ec
https://pubmed.ncbi.nlm.nih.gov/36483092
https://pubmed.ncbi.nlm.nih.gov/36483092
Autor:
Yuko Shimizu-Motohashi, Emiko Chiba, Katsuhiro Mizuno, Hiroyuki Yajima, Akihiko Ishiyama, Eri Takeshita, Noriko Sato, Mari Oba, Masayuki Sasaki, Shuichi Ito, Hirofumi Komaki
BACKGROUNDReal-world data have shown variability in treatment responses to nusinersen in patients with 5q spinal muscular atrophy (SMA). It could be hypothesized that the degree of muscle impairment may confer to the drug response variability. Magnet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05f6bdc02d6cc0c33feb59dfc497a5ff
https://doi.org/10.21203/rs.3.rs-1647645/v1
https://doi.org/10.21203/rs.3.rs-1647645/v1
Autor:
Shinnosuke Masuda, Oh Kwan Ee, Taku James Sairenji, Seika Sato, Hiroyuki Yajima, Izuki Amano, Noriyuki Koibuchi, Noriaki Shimokawa
Publikováno v:
Developmental Psychobiology. 64
Elucidating the mechanisms underlying nurturing and neglect behaviors is meaningful but challenging. Recently, we found that CIN85-deficient mice had reduced pituitary hormone prolactin secretion during late pregnancy, and their pups later showed an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b92c16a602dc9e16d39fbd72dc00313
https://doi.org/10.1002/dev.22264
https://doi.org/10.1002/dev.22264